Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults

Clinical value of liver ultrasound for the diagnosis of nonalcoholic fatty liver disease in overweight and obese patients

(2015) Fernando Bril et al.   LIVER INTERNATIONAL

Neck Circumference, along with Other Anthropometric Indices, Has an Independent and Additional Contribution in Predicting Fatty Liver Disease

(2015) Bi-xia Huang et al.   PLoS One

Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide

(2014) Z. Wang et al.   EUROPEAN HEART JOURNAL

Higher serum concentrations of betaine rather than choline is associated with better profiles of DXA-derived body fat and fat distribution in Chinese adults

(2014) Y-m Chen et al.   INTERNATIONAL JOURNAL OF OBESITY

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

(2014) Xiang Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure

(2014) M. Trøseid et al.   JOURNAL OF INTERNAL MEDICINE

Higher Dietary Choline Intake Is Associated with Lower Risk of Nonalcoholic Fatty Liver in Normal-Weight Chinese Women

(2014) Danxia Yu et al.   JOURNAL OF NUTRITION

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure

(2014) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study

(2014) Michael Lever et al.   PLoS One

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

Role of diet and nutritional management in non-alcoholic fatty liver disease

(2013) Jian-Gao Fan et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Epidemiology of alcoholic and nonalcoholic fatty liver disease in China

(2013) Jian-Gao Fan   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Betaine attenuates hepatic steatosis by reducing methylation of the MTTP promoter and elevating genomic methylation in mice fed a high-fat diet

(2013) Li-jun Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of Dietary Supplementation with Betaine on a Nonalcoholic Steatohepatitis (NASH) Mouse Model

(2013) Sakura KAWAKAMI et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

NAFLD in Asia—as common and important as in the West

(2013) Geoffrey C. Farrell et al.   Nature Reviews Gastroenterology & Hepatology

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Choline intake in a large cohort of patients with nonalcoholic fatty liver disease

(2012) Anthony L Guerrerio et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

Plasma free choline is a novel non-invasive biomarker for early-stage non-alcoholic steatohepatitis: A multi-center validation study

(2012) Kento Imajo et al.   HEPATOLOGY RESEARCH

Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women

(2011) Julie M. W. Wallace et al.   BRITISH JOURNAL OF NUTRITION

Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression

(2011) Karen D. Corbin et al.   CURRENT OPINION IN GASTROENTEROLOGY

Endpoints and clinical trial design for nonalcoholic steatohepatitis

(2011) Arun J. Sanyal et al.   HEPATOLOGY

Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: A meta-analysis

(2011) Ruben Hernaez et al.   HEPATOLOGY

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Choline and betaine in health and disease

(2010) Per Magne Ueland   JOURNAL OF INHERITED METABOLIC DISEASE

Betaine for nonalcoholic fatty liver disease: Results of a randomized placebo-controlled trial

(2009) Manal F. Abdelmalek et al.   HEPATOLOGY

Guidelines for the diagnosis and treatment of nonalcoholic fatty liver diseases

(2008) Min De ZENG et al.   Journal of Digestive Diseases