Neutrophils in chronic inflammatory diseases

Orchestration of Neutrophil Extracellular Traps (Nets), a Unique Innate Immune Function during Chronic Obstructive Pulmonary Disease (COPD) Development

(2021) Anjali Trivedi et al.   Biomedicines

Triggering Receptor Expressed on Myeloid Cells-1 Agonist Regulates Intestinal Inflammation via Cd177+ Neutrophils

(2021) Dong Hyuk Seo et al.   Frontiers in Immunology

Neutrophils in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus: Same Foe Different M.O.

(2021) Michele Fresneda Alarcon et al.   Frontiers in Immunology

Multi-omics links IL-6 trans-signalling with neutrophil extracellular trap formation and Haemophilus infection in COPD

(2021) Sofia Winslow et al.   EUROPEAN RESPIRATORY JOURNAL

Innate Immune Cells in the Adipose Tissue in Health and Metabolic Disease

(2021) Zoi Michailidou et al.   Journal of Innate Immunity

Targeting inflammation in atherosclerosis — from experimental insights to the clinic

(2021) Oliver Soehnlein et al.   NATURE REVIEWS DRUG DISCOVERY

The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments

(2021) Ricardo Grieshaber-Bouyer et al.   Nature Communications

Neutrophil extracellular traps induced by pro-inflammatory cytokines enhance procoagulant activity in NASH patients

(2021) Jingwen Du et al.   Clinics and Research in Hepatology and Gastroenterology

Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps

(2021) Wanfa Dong et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Peptidylarginine Deiminase 4 as a Possible Biomarker of Plaque Instability in Carotid Artery Stenosis

(2021) Koji Shimonaga et al.   Journal of Stroke & Cerebrovascular Diseases

Associations of NETs with inflammatory risk and atherosclerotic severity in ST-segment elevation myocardial infarction

(2021) Jinying Zhou et al.   THROMBOSIS RESEARCH

Kinetics of Neutrophil Subsets in Acute, Subacute, and Chronic Inflammation

(2021) Suzanne H. Bongers et al.   Frontiers in Immunology

Low-Density Neutrophils in Healthy Individuals Display a Mature Primed Phenotype

(2021) Carlos Blanco-Camarillo et al.   Frontiers in Immunology

The Enigma of Low-Density Granulocytes in Humans: Complexities in the Characterization and Function of LDGs during Disease

(2021) Brittany G. Seman et al.   Pathogens

Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD

(2020) Andreea-Manuela Mirea et al.   INFLAMMATION

The Diabetes Mellitus–Atherosclerosis Connection: The Role of Lipid and Glucose Metabolism and Chronic Inflammation

(2020) Anastasia Poznyak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutrophils as regulators of cardiovascular inflammation

(2020) Carlos Silvestre-Roig et al.   Nature Reviews Cardiology

Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases

(2020) Renato G. S. Chirivi et al.   Cellular & Molecular Immunology

Diagnostic utility of the neutrophil-platelet ratio as a novel marker of activity in patients with Ulcerative Colitis

(2020) Jesús K. Yamamoto-Furusho et al.   PLoS One

Circadian Features of Neutrophil Biology

(2020) Alejandra Aroca-Crevillén et al.   Frontiers in Immunology

Neutrophil Extracellular Trap Induced Dendritic Cell Activation Leads to Th1 Polarization in Type 1 Diabetes

(2020) Zuzana Parackova et al.   Frontiers in Immunology

Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis

(2020) Michelle C Flynn et al.   CIRCULATION RESEARCH

Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice

(2020) Lingling Shu et al.   CLINICAL SCIENCE

Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner

(2020) Anandita Pal et al.   FASEB JOURNAL

miR-146a is a pivotal regulator of neutrophil extracellular trap formation promoting thrombosis

(2020) Ana B. Arroyo et al.   HAEMATOLOGICA

Neutrophils: Underestimated Players in the Pathogenesis of Multiple Sclerosis (MS)

(2020) Mirre De Bondt et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

(2020) Xuemei Xie et al.   NATURE IMMUNOLOGY

Increased Neutrophil Extracellular Traps Related to Smoking Intensity and Subclinical Atherosclerosis in Patients with Type 2 Diabetes

(2020) Michael Koutsilieris et al.   THROMBOSIS AND HAEMOSTASIS

Circulating Neutrophils of Nonalcoholic Steatohepatitis Patients Show an Activated Phenotype and Suppress T Lymphocytes Activity

(2020) Laura Antonucci et al.   Journal of Immunology Research

B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure

(2020) Mégane Nascimento et al.   Frontiers in Immunology

MK2 Is Required for Neutrophil-Derived ROS Production and Inflammatory Bowel Disease

(2020) Tao Zhang et al.   Frontiers in Medicine

Inhibition of Interleukin-1β and Reduction in Atherothrombotic Cardiovascular Events in the CANTOS Trial

(2020) Brendan M. Everett et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Atlas of Inflammation Resolution (AIR)

(2020) Charles N. Serhan et al.   MOLECULAR ASPECTS OF MEDICINE

Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge–Mediated Monocyte Adhesion

(2020) Ariane Schumski et al.   CIRCULATION

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

(2020) Fernanda M.C. Sodré et al.   DIABETES

Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019

(2020) Gregory A. Roth et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis

(2020) Hendy Kristyanto et al.   Science Translational Medicine

Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

(2020) María Crespo et al.   eLife

Chronic Inflammation in Non-Alcoholic Steatohepatitis: Molecular Mechanisms and Therapeutic Strategies

(2020) Carmelo Luci et al.   Frontiers in Endocrinology

Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223–enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis

(2020) Yong He et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia

(2019) José Perdomo et al.   Nature Communications

Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling Disease

(2019) Liam J. O’Neil et al.   TRENDS IN MOLECULAR MEDICINE

Ameliorating gut microenvironment through staphylococcal nuclease-mediated intestinal NETs degradation for prevention of type 1 diabetes in NOD mice

(2019) Yixuan Liang et al.   LIFE SCIENCES

Neutrophil Extracellular Traps Sustain Inflammatory Signals in Ulcerative Colitis

(2019) Vincenzo Dinallo et al.   Journal of Crohns & Colitis

Neutrophil extracellular traps exert both pro- and anti-inflammatory actions in rheumatoid arthritis that are modulated by C1q and LL-37

(2019) Matthieu Ribon et al.   JOURNAL OF AUTOIMMUNITY

Neutrophil–macrophage cooperation and its impact on tissue repair

(2019) Tiffany Bouchery et al.   IMMUNOLOGY AND CELL BIOLOGY

Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates

(2019) Luca Cassetta et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

CCSP counterbalances airway epithelial-driven neutrophilic chemotaxis

(2019) Lucie Knabe et al.   EUROPEAN RESPIRATORY JOURNAL

Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice

(2019) Taylor S. Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

(2019) Andreea-Manuela Mirea et al.   MOLECULAR MEDICINE

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death

(2019) Carlos Silvestre-Roig et al.   NATURE

Bidirectional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation

(2019) Yasuharu Watanabe et al.   FASEB JOURNAL

More friend than foe: the emerging role of neutrophils in tissue repair

(2019) Moritz Peiseler et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil Extracellular Traps Induce Intestinal Damage and Thrombotic Tendency in Inflammatory Bowel Disease

(2019) Tao Li et al.   Journal of Crohns & Colitis

The Global Epidemiology of NAFLD and NASH in Patients with type 2 diabetes: A Systematic Review and Meta-analysis

(2019) Zobair M. Younossi et al.   JOURNAL OF HEPATOLOGY

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair

(2019) Bartolo Ferraro et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Platelet–Neutrophil Crosstalk in Atherothrombosis

(2019) Joachim Pircher et al.   THROMBOSIS AND HAEMOSTASIS

Neutrophil Diversity in Health and Disease

(2019) Carlos Silvestre-Roig et al.   TRENDS IN IMMUNOLOGY

Changes in innate and adaptive immunity over the first year after the onset of type 1 diabetes

(2019) Adam Klocperk et al.   ACTA DIABETOLOGICA

Synthetic cathelicidin LL-37 reduces Mycobacterium avium subsp. paratuberculosis internalization and pro-inflammatory cytokines in macrophages

(2019) Karina M. Cirone et al.   CELL AND TISSUE RESEARCH

Effect of weight loss on neutrophil resolvins in the metabolic syndrome

(2019) A. Barden et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A Proresolving Peptide Nanotherapy for Site‐Specific Treatment of Inflammatory Bowel Disease by Regulating Proinflammatory Microenvironment and Gut Microbiota

(2019) Chenwen Li et al.   Advanced Science

Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis

(2019) Franziska Herster et al.   Frontiers in Immunology

Neutrophil Heterogeneity in Cancer: From Biology to Therapies

(2019) Pacôme Lecot et al.   Frontiers in Immunology

Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism

(2019) Jin Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interleukin‐22 ameliorates neutrophil‐driven nonalcoholic steatohepatitis through multiple targets

(2019) Seonghwan Hwang et al.   HEPATOLOGY

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

(2019) Pragnesh Mistry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Misunderstandings Between Platelets and Neutrophils Build in Chronic Inflammation

(2019) Giuseppe A. Ramirez et al.   Frontiers in Immunology

Chronic inflammation in the etiology of disease across the life span

(2019) David Furman et al.   NATURE MEDICINE

Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failure

(2019) Bochra Tourki et al.   Molecular Metabolism

NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages

(2018) Juhi Bagaitkar et al.   BLOOD

Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease

(2018) Kathryn Prame Kumar et al.   CELL AND TISSUE RESEARCH

Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis

(2018) Carla Winter et al.   Cell Metabolism

Phenotypic and functional changes of GM-CSF differentiated human macrophages following exposure to apoptotic neutrophils

(2018) Elena R. Chernykh et al.   CELLULAR IMMUNOLOGY

ERV1/ChemR23 Signaling Protects from Atherosclerosis by Modifying oxLDL Uptake and Phagocytosis in Macrophages

(2018) Andres Laguna-Fernandez et al.   CIRCULATION

Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial InjuryNovelty and Significance

(2018) Grégory Franck et al.   CIRCULATION RESEARCH

Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis

(2018) Dirk J. van der Windt et al.   HEPATOLOGY

Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease

(2018) Alison J. Dicker et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Netting Neutrophils Activate Autoreactive B Cells in Lupus

(2018) Nicolas Gestermann et al.   JOURNAL OF IMMUNOLOGY

Type 1 diabetes

(2018) Linda A DiMeglio et al.   LANCET

Myeloid-derived suppressor cells coming of age

(2018) Filippo Veglia et al.   NATURE IMMUNOLOGY

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation

(2018) John A. Marwick et al.   Cell Death & Disease

Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation

(2018) Joachim Pircher et al.   Nature Communications

The Role of NOD Mice in Type 1 Diabetes Research: Lessons from the Past and Recommendations for the Future

(2018) Yi-Guang Chen et al.   Frontiers in Endocrinology

Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks

(2018) Theingi Aung et al.   JAMA Cardiology

Neutrophil Microvesicles from Healthy Control and Rheumatoid Arthritis Patients Prevent the Inflammatory Activation of Macrophages

(2018) Hefin I. Rhys et al.   EBioMedicine

Recent advances on the crosstalk between neutrophils and B or T lymphocytes

(2018) Sara Costa et al.   IMMUNOLOGY

Ability of Platelet-Derived Extracellular Vesicles to Promote Neutrophil-Endothelial Cell Interactions

(2018) Sahithi J. Kuravi et al.   INFLAMMATION

Start a fire, kill the bug: The role of platelets in inflammation and infection

(2018) Carsten Deppermann et al.   Innate Immunity

Neutrophils Promote Amphiregulin Production in Intestinal Epithelial Cells through TGF-β and Contribute to Intestinal Homeostasis

(2018) Feidi Chen et al.   JOURNAL OF IMMUNOLOGY

Neutrophil elastase and myeloperoxidase mRNA expression in overweight and obese subjects

(2018) Mohammad Ali et al.   MOLECULAR BIOLOGY REPORTS

The parallel worlds of ACPA-positive and RF-positive B cells

(2018) Vivianne Malmström et al.   Nature Reviews Rheumatology

Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis

(2018) Norma Maugeri et al.   Science Translational Medicine

Platelet-neutrophil interaction aggravates vascular inflammation and promotes the progression of atherosclerosis by activating the TLR4/NF-κB pathway

(2018) Xiao Liang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Gregory A Roth et al.   LANCET

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

(2018) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increased formations of neutrophil extracellular traps are associated with gut leakage in the patients with type 1 diabetes but not type 2 diabetes

(2018) Qi You et al.   Journal of Diabetes

The Emerging Role of Neutrophil Granulocytes in Multiple Sclerosis

(2018) Tonia Woodberry et al.   Journal of Clinical Medicine

CD177+neutrophils as functionally activated neutrophils negatively regulate IBD

(2017) Guangxi Zhou et al.   GUT

A functional characteristic of cysteine-rich protein 61: Modulation of myeloid-derived suppressor cells in liver inflammation

(2017) Haiyan Zhang et al.   HEPATOLOGY

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes

(2017) Michael J. Kraakman et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic obstructive pulmonary disease

(2017) Klaus F Rabe et al.   LANCET

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammaging and ‘Garb-aging’

(2017) Claudio Franceschi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Association of a variant in the gene encoding for ERV1/ChemR23 with reduced inflammation in visceral adipose tissue from morbidly obese individuals

(2017) Cristina López-Vicario et al.   Scientific Reports

Myeloid-Derived Suppressor Cells

(2017) Dmitry I. Gabrilovich   Cancer Immunology Research

NETosis-associated serum biomarkers are reduced in type 1 diabetes in association with neutrophil count

(2016) J. Qin et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

p38  and p38  reprogram liver metabolism by modulating neutrophil infiltration

(2016) B. Gonzalez-Teran et al.   EMBO JOURNAL

Human neutrophils in the saga of cellular heterogeneity: insights and open questions

(2016) Patrizia Scapini et al.   IMMUNOLOGICAL REVIEWS

The responses of macrophages in interaction with neutrophils that undergo NETosis

(2016) Daigo Nakazawa et al.   JOURNAL OF AUTOIMMUNITY

The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes

(2016) James A. Pearson et al.   JOURNAL OF AUTOIMMUNITY

Concomitant elevations of MMP-9, NGAL, proMMP-9/NGAL and neutrophil elastase in serum of smokers with chronic obstructive pulmonary disease

(2016) Sarra Bchir et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lipocalin-2 mediates non-alcoholic steatohepatitis by promoting neutrophil-macrophage crosstalk via the induction of CXCR2

(2016) Dewei Ye et al.   JOURNAL OF HEPATOLOGY

Alarmin S100A9 Induces Proinflammatory and Catabolic Effects Predominantly in the M1 Macrophages of Human Osteoarthritic Synovium

(2016) M. H. van den Bosch et al.   JOURNAL OF RHEUMATOLOGY

Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance

(2016) Erik JM Toonen et al.   MOLECULAR MEDICINE

The Dual Role of Neutrophils in Inflammatory Bowel Diseases

(2016) Odile Wéra et al.   Journal of Clinical Medicine

CXCR2 Antagonist MK-7123. A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease

(2015) Stephen I. Rennard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Myeloperoxidase–Hepatocyte–Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic Steatohepatitis

(2015) Benjamin Pulli et al.   ANTIOXIDANTS & REDOX SIGNALING

Neutrophils Play a Crucial Role in the Early Stage of Nonalcoholic Steatohepatitis via Neutrophil Elastase in Mice

(2015) Shufei Zang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Increased ratio of neutrophil elastase toα1-antitrypsin is closely associated with liver inflammation in patients with nonalcoholic steatohepatitis

(2015) Shufei Zang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Neutrophil proteases alter the interleukin-22-receptor-dependent lung antimicrobial defence

(2015) Antoine Guillon et al.   EUROPEAN RESPIRATORY JOURNAL

LL-37 Immunomodulatory Activity during Mycobacterium tuberculosis Infection in Macrophages

(2015) Flor Torres-Juarez et al.   INFECTION AND IMMUNITY

Human autoimmune diseases: a comprehensive update

(2015) Lifeng Wang et al.   JOURNAL OF INTERNAL MEDICINE

Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis

(2015) Alyssa D. Gregory et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

(2015) Siu Ling Wong et al.   NATURE MEDICINE

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

MicroRNA-155 Deficiency Results in Decreased Macrophage Inflammation and Attenuated Atherogenesis in Apolipoprotein E–Deficient Mice

(2014) Fen Du et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis

(2014) Jason S. Knight et al.   CIRCULATION RESEARCH

Myeloperoxidase Deletion Prevents High-Fat Diet-Induced Obesity and Insulin Resistance

(2014) Q. Wang et al.   DIABETES

Increased Neutrophil Elastase and Proteinase 3 and Augmented NETosis Are Closely Associated With  -Cell Autoimmunity in Patients With Type 1 Diabetes

(2014) Y. Wang et al.   DIABETES

Macrophages and  -cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes

(2014) J. Diana et al.   EMBO Molecular Medicine

Neutrophil extracellular traps promote differentiation and function of fibroblasts

(2014) Akrivi Chrysanthopoulou et al.   JOURNAL OF PATHOLOGY

Neutrophils scan for activated platelets to initiate inflammation

(2014) Vinatha Sreeramkumar et al.   SCIENCE

Inflammatory bowel disease: Pathogenesis

(2014) Yi-Zhen Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Neutrophil-Derived Cytokines: Facts Beyond Expression

(2014) Cristina Tecchio et al.   Frontiers in Immunology

The Neutrophil in Chronic Obstructive Pulmonary Disease. Too Little, Too Late or Too Much, Too Soon?

(2013) Kim Hoenderdos et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Imbalance between Neutrophil Elastase and its Inhibitor α1-Antitrypsin in Obesity Alters Insulin Sensitivity, Inflammation, and Energy Expenditure

(2013) Virginie Mansuy-Aubert et al.   Cell Metabolism

Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes

(2013) A. Valle et al.   DIABETES

Resolution of inflammation: an integrated view

(2013) Almudena Ortega-Gómez et al.   EMBO Molecular Medicine

Reduced Blood Leukocyte and Neutrophil Numbers in the Pathogenesis of Type 1 Diabetes

(2013) M. Harsunen et al.   HORMONE AND METABOLIC RESEARCH

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis

(2013) C. L. Zindl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal Models of Atherosclerosis

(2012) Godfrey S. Getz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

(2012) Saswata Talukdar et al.   NATURE MEDICINE

Neutrophil-Derived Myeloperoxidase Aggravates Non-Alcoholic Steatohepatitis in Low-Density Lipoprotein Receptor-Deficient Mice

(2012) Sander S. Rensen et al.   PLoS One

Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation

(2012) D. El Kebir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Late Intervention with a Myeloperoxidase Inhibitor Stops Progression of Experimental Chronic Obstructive Pulmonary Disease

(2011) Andrew Churg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses

(2011) K. L. Brown et al.   JOURNAL OF IMMUNOLOGY

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Neutrophil transmigration triggers repair of the lung epithelium via  -catenin signaling

(2011) R. L. Zemans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cigarette smoke-exposed neutrophils die unconventionally but are rapidly phagocytosed by macrophages

(2011) K Guzik et al.   Cell Death & Disease

Epithelial repair mechanisms in the lung

(2010) Lynn M. Crosby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Genetics, pathogenesis and clinical interventions in type 1 diabetes

(2010) Jeffrey A. Bluestone et al.   NATURE

Increased Hepatic Myeloperoxidase Activity in Obese Subjects with Nonalcoholic Steatohepatitis

(2009) Sander S. Rensen et al.   AMERICAN JOURNAL OF PATHOLOGY

Cigarette Smoke Impairs Clearance of Apoptotic Cells through Oxidant-dependent Activation of RhoA

(2009) Tiffany R. Richens et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mechanisms underlying neutrophil-mediated monocyte recruitment

(2009) O. Soehnlein et al.   BLOOD

Neutrophil Activation in Morbid Obesity, Chronic Activation of Acute Inflammation

(2009) Jeroen Nijhuis et al.   Obesity

Neutrophil secretion products pave the way for inflammatory monocytes

(2008) O. Soehnlein et al.   BLOOD

Neutrophil primary granule proteins HBP and HNP1–3 boost bacterial phagocytosis by human and murine macrophages

(2008) Oliver Soehnlein et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding

(2008) Vered Elgazar-Carmon et al.   JOURNAL OF LIPID RESEARCH