A Proresolving Peptide Nanotherapy for Site‐Specific Treatment of Inflammatory Bowel Disease by Regulating Proinflammatory Microenvironment and Gut Microbiota

An ingestible self-orienting system for oral delivery of macromolecules

(2019) Alex Abramson et al.   SCIENCE

Silencing of Intestinal Glycoprotein CD98 by Orally Targeted Nanoparticles Enhances Chemosensitization of Colon Cancer

(2018) Bo Xiao et al.   ACS Nano

Self-assembly of affinity-controlled nanoparticles via host–guest interactions for drug delivery

(2018) Fangchao Xue et al.   Nanoscale

Precision editing of the gut microbiota ameliorates colitis

(2018) Wenhan Zhu et al.   NATURE

A Broad-Spectrum ROS-Eliminating Material for Prevention of Inflammation and Drug-Induced Organ Toxicity

(2018) Lanlan Li et al.   Advanced Science

Local delivery of macromolecules to treat diseases associated with the colon

(2018) A. Bak et al.   ADVANCED DRUG DELIVERY REVIEWS

A Targeting Nanotherapy for Abdominal Aortic Aneurysms

(2018) Juan Cheng et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Understanding and Preventing the Global Increase of Inflammatory Bowel Disease

(2017) Gilaad G. Kaplan et al.   GASTROENTEROLOGY

Bioinspired yeast microcapsules loaded with self-assembled nanotherapies for targeted treatment of cardiovascular disease

(2017) Xiangjun Zhang et al.   Materials Today

Gut permeability and mucosal inflammation: bad, good or context dependent

(2017) R Ahmad et al.   Mucosal Immunology

Yeast Microcapsule-Mediated Targeted Delivery of Diverse Nanoparticles for Imaging and Therapy via the Oral Route

(2017) Xing Zhou et al.   NANO LETTERS

Nanoparticulate drug delivery systems targeting inflammation for treatment of inflammatory bowel disease

(2017) Sufeng Zhang et al.   Nano Today

Chemically induced mouse models of acute and chronic intestinal inflammation

(2017) Stefan Wirtz et al.   Nature Protocols

Physical, Chemical, and Biological Structures based on ROS-Sensitive Moieties that are Able to Respond to Oxidative Microenvironments

(2016) Christos Tapeinos et al.   ADVANCED MATERIALS

Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis

(2016) Shibin Feng et al.   BIOMATERIALS

A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease

(2016) Qixiong Zhang et al.   BIOMATERIALS

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

Oral, ultra–long-lasting drug delivery: Application toward malaria elimination goals

(2016) Andrew M. Bellinger et al.   Science Translational Medicine

Reactive-Oxygen-Species-Responsive Drug Delivery Systems: Promises and Challenges

(2016) Gurusamy Saravanakumar et al.   Advanced Science

The gut microbiota and host health: a new clinical frontier

(2015) Julian R Marchesi et al.   GUT

Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair

(2015) Giovanna Leoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Wound repair: role of immune–epithelial interactions

(2015) G Leoni et al.   Mucosal Immunology

A pH-responsive supramolecular polymer gel as an enteric elastomer for use in gastric devices

(2015) Shiyi Zhang et al.   NATURE MATERIALS

Nanomedicines in gastroenterology and hepatology

(2015) Alf Lamprecht   Nature Reviews Gastroenterology & Hepatology

Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice

(2015) Gabrielle Fredman et al.   Science Translational Medicine

The resolution of inflammation: Principles and challenges

(2015) Sarah E. Headland et al.   SEMINARS IN IMMUNOLOGY

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

Nanoparticles With Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice

(2014) Bo Xiao et al.   GASTROENTEROLOGY

Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases

(2014) Asima Bhattacharyya et al.   PHYSIOLOGICAL REVIEWS

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biocompatible Reactive Oxygen Species (ROS)-Responsive Nanoparticles as Superior Drug Delivery Vehicles

(2014) Dinglin Zhang et al.   Advanced Healthcare Materials

Drug delivery strategies in the therapy of inflammatory bowel disease

(2013) Christian Lautenschläger et al.   ADVANCED DRUG DELIVERY REVIEWS

The Inflammatory Tissue Microenvironment in IBD

(2013) Sean P. Colgan et al.   INFLAMMATORY BOWEL DISEASES

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Annexin A1: potential for glucocorticoid sparing in RA

(2013) Yuan H. Yang et al.   Nature Reviews Rheumatology

Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles

(2013) N. Kamaly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery

(2013) E. M. Pridgen et al.   Science Translational Medicine

An Orally Administered Redox Nanoparticle That Accumulates in the Colonic Mucosa and Reduces Colitis in Mice

(2012) Long Binh Vong et al.   GASTROENTEROLOGY

The gut microbiota in IBD

(2012) Chaysavanh Manichanh et al.   Nature Reviews Gastroenterology & Hepatology

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Regulation of Inflammation by Short Chain Fatty Acids

(2011) Marco A.R. Vinolo et al.   Nutrients

Biological Therapies for Inflammatory Bowel Diseases

(2009) Paul Rutgeerts et al.   GASTROENTEROLOGY

Drug-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduce Colitis in a Mouse Model

(2009) Hamed Laroui et al.   GASTROENTEROLOGY

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE