Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis

The B cell response to citrullinated antigens in the development of rheumatoid arthritis

(2018) Hans Ulrich Scherer et al.   Nature Reviews Rheumatology

Generation and characterization of anti-citrullinated protein antibody-producing B-cell clones from rheumatoid arthritis patients

(2018) Kristine Germar et al.   Arthritis & Rheumatology

EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis

(2016) Hanna W van Steenbergen et al.   ANNALS OF THE RHEUMATIC DISEASES

Synovial fluid mononuclear cells provide an environment for long-term survival of antibody-secreting cells and promote the spontaneous production of anti-citrullinated protein antibodies

(2016) Priscilla F Kerkman et al.   ANNALS OF THE RHEUMATIC DISEASES

Tapering biologic and conventional DMARD therapy in rheumatoid arthritis: current evidence and future directions

(2016) Georg Schett et al.   ANNALS OF THE RHEUMATIC DISEASES

Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination

(2016) Ali H Ellebedy et al.   NATURE IMMUNOLOGY

Clinical factors, anticitrullinated peptide antibodies and MRI-detected subclinical inflammation in relation to progression from clinically suspect arthralgia to arthritis

(2015) Hanna W van Steenbergen et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification and characterisation of citrullinated antigen-specific B cells in peripheral blood of patients with rheumatoid arthritis

(2015) Priscilla F Kerkman et al.   ANNALS OF THE RHEUMATIC DISEASES

B cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody production

(2015) Shaun W Jackson et al.   CURRENT OPINION IN IMMUNOLOGY

The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases

(2014) Remo C Russo et al.   Expert Review of Clinical Immunology

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Brief Report: Anti-Citrullinated Protein Antibody Positivity Correlates With Cartilage Damage and Proteoglycan Levels in Patients With Rheumatoid Arthritis in the Hand Joints

(2014) Nina Renner et al.   Arthritis & Rheumatology

Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies

(2013) Arnd Kleyer et al.   ANNALS OF THE RHEUMATIC DISEASES

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

(2013) Aase Haj Hensvold et al.   ANNALS OF THE RHEUMATIC DISEASES

CD40 Mediates Downregulation of CD32B on Specific Memory B Cell Populations in Rheumatoid Arthritis

(2013) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Features of the Synovium of Individuals at Risk of Developing Rheumatoid Arthritis: Implications for Understanding Preclinical Rheumatoid Arthritis

(2013) M. J. H. de Hair et al.   Arthritis & Rheumatology

CD80 Expression on B Cells Regulates Murine T Follicular Helper Development, Germinal Center B Cell Survival, and Plasma Cell Generation

(2012) K. L. Good-Jacobson et al.   JOURNAL OF IMMUNOLOGY

The influence of ACPA status and characteristics on the course of RA

(2012) Annemiek Willemze et al.   Nature Reviews Rheumatology

Highest clinical effectiveness of rituximab in autoantibody-positive patients with rheumatoid arthritis and in those for whom no more than one previous TNF antagonist has failed: pooled data from 10 European registries

(2011) K. Chatzidionysiou et al.   ANNALS OF THE RHEUMATIC DISEASES

Fc  receptor profile of monocytes and macrophages from rheumatoid arthritis patients and their response to immune complexes formed with autoantibodies to citrullinated proteins

(2011) L. Laurent et al.   ANNALS OF THE RHEUMATIC DISEASES

Development of the anti-citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis

(2011) Lotte A. van de Stadt et al.   ARTHRITIS AND RHEUMATISM

Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis

(2011) P. Suwannalai et al.   ARTHRITIS AND RHEUMATISM

Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

(2010) D. van der Woude et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

(2010) A. Ioan-Facsinay et al.   ANNALS OF THE RHEUMATIC DISEASES

Different stages of rheumatoid arthritis: features of the synovium in the preclinical phase

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor

(2010) Jeremy Sokolove et al.   ARTHRITIS AND RHEUMATISM

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

(2009) L. A. Trouw et al.   ARTHRITIS AND RHEUMATISM

Generation of stable monoclonal antibody–producing B cell receptor–positive human memory B cells by genetic programming

(2009) Mark J Kwakkenbos et al.   NATURE MEDICINE

B cells in autoimmunity

(2009) Thomas Dörner et al.   ARTHRITIS RESEARCH & THERAPY