Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythematosus

(2019) Saifur Rahman et al.   ANNALS OF THE RHEUMATIC DISEASES

Genomic Identification of Low-Density Granulocytes and Analysis of Their Role in the Pathogenesis of Systemic Lupus Erythematosus

(2019) Brian J. Kegerreis et al.   JOURNAL OF IMMUNOLOGY

Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

(2018) Maximilien Evrard et al.   IMMUNITY

Type I IFN–related NETosis in ataxia telangiectasia and Artemis deficiency

(2018) Ersin Gul et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis

(2018) Shelley M. Lawrence et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Neutrophil extracellular trap release is associated with antinuclear antibodies in systemic lupus erythematosus and anti-phospholipid syndrome

(2018) Maarten van der Linden et al.   RHEUMATOLOGY

Dysregulated neutrophil responses and neutrophil extracellular trap formation and degradation in PAPA syndrome

(2018) Pragnesh Mistry et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophils in cardiovascular disease

(2017) Daniel S. Gaul et al.   EUROPEAN HEART JOURNAL

IRF3 and type I interferons fuel a fatal response to myocardial infarction

(2017) Kevin R King et al.   NATURE MEDICINE

Low-density granulocytes: functionally distinct, immature neutrophils in rheumatoid arthritis with altered properties and defective TNF signalling

(2016) Helen L. Wright et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

Distinct Functions of Autoantibodies Against Interferon in Systemic Lupus Erythematosus: A Comprehensive Analysis of Anticytokine Autoantibodies in Common Rheumatic Diseases

(2016) Sarthak Gupta et al.   Arthritis & Rheumatology

IRF8 acts in lineage-committed rather than oligopotent progenitors to control neutrophil vs monocyte production

(2015) A. Yanez et al.   BLOOD

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils

(2015) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

Host Transcriptional Response to Influenza and Other Acute Respiratory Viral Infections – A Prospective Cohort Study

(2015) Yijie Zhai et al.   PLoS Pathogens

Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

(2015) Peter C. Grayson et al.   Arthritis & Rheumatology

Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2

(2014) Carmelo Carmona-Rivera et al.   ANNALS OF THE RHEUMATIC DISEASES

Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis

(2014) Jason S. Knight et al.   CIRCULATION RESEARCH

Neutrophil Extracellular Trap-Derived Enzymes Oxidize High-Density Lipoprotein: An Additional Proatherogenic Mechanism in Systemic Lupus Erythematosus

(2014) Carolyne K. Smith et al.   Arthritis & Rheumatology

Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity

(2013) Carmelo Carmona-Rivera et al.   Seminars in Immunopathology

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis

(2011) A. M. Lin et al.   JOURNAL OF IMMUNOLOGY

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs

(2010) M. F. Denny et al.   JOURNAL OF IMMUNOLOGY

Ninjurin1 is expressed in myeloid cells and mediates endothelium adhesion in the brains of EAE rats

(2009) Bum Ju Ahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neutrophil secretion products pave the way for inflammatory monocytes

(2008) O. Soehnlein et al.   BLOOD

The role of chemokines in neutrophil biology

(2007) Yoshiro Kobayashi   Frontiers in Bioscience-Landmark