Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD

IL-1 Family Cytokine Pathways Underlying NAFLD: Towards New Treatment Strategies

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Adipokines and Non-Alcoholic Fatty Liver Disease: Multiple Interactions

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NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

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Adipose tissue inflammation: a cause or consequence of obesity-related insulin resistance?

(2016) M. Bluher   CLINICAL SCIENCE

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Neutral serine proteases of neutrophils

(2016) Ralph Kettritz   IMMUNOLOGICAL REVIEWS

Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance

(2016) Erik JM Toonen et al.   MOLECULAR MEDICINE

Role of NLRP3 Inflammasome in the Progression of NAFLD to NASH

(2016) Xingyong Wan et al.   Canadian Journal of Gastroenterology and Hepatology

Increased ratio of neutrophil elastase toα1-antitrypsin is closely associated with liver inflammation in patients with nonalcoholic steatohepatitis

(2015) Shufei Zang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme

(2015) Inna S. Afonina et al.   IMMUNITY

Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management

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Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

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NLRP3 inflammasome activation is required for fibrosis development in NAFLD

(2014) Alexander Wree et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Risk of cardiovascular, cardiac and arrhythmic complications in patients with non-alcoholic fatty liver disease

(2014) Stefano Ballestri   WORLD JOURNAL OF GASTROENTEROLOGY

Imbalance between Neutrophil Elastase and its Inhibitor α1-Antitrypsin in Obesity Alters Insulin Sensitivity, Inflammation, and Energy Expenditure

(2013) Virginie Mansuy-Aubert et al.   Cell Metabolism

Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis

(2013) Laura J. Dixon et al.   PLoS One

Inhibition of Hypothalamic Inflammation Reverses Diet-Induced Insulin Resistance in the Liver

(2012) M. Milanski et al.   DIABETES

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

(2012) Hye-Mi Lee et al.   DIABETES

Sterile Inflammation in the Liver

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Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis

(2012) Laura J Dixon et al.   LABORATORY INVESTIGATION

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity

(2010) Rinke Stienstra et al.   Cell Metabolism

Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases

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Neutrophil serine proteases fine-tune the inflammatory response

(2007) C PHAM   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY