Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation
Authors
Keywords
-
Journal
Nature Communications
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-07-17
DOI
10.1038/s41467-017-00213-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study
- (2017) Stephan Vavricka et al. BMJ Open
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- High Altitude Journeys, Flights and Hypoxia: Any Role for Disease Flares in IBD Patients?
- (2016) Stephan R. Vavricka et al. DIGESTIVE DISEASES
- Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome
- (2016) Pedro A Ruiz et al. GUT
- Modulation of inflammation by autophagy: Consequences for human disease
- (2015) Romana T. Netea-Maier et al. Autophagy
- Exposome in IBD
- (2015) Gerhard Rogler et al. INFLAMMATORY BOWEL DISEASES
- Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IκB
- (2015) Kamila Müller-Edenborn et al. Oncotarget
- Activation of HIF-1α does not increase intestinal tumorigenesis
- (2014) Xiang Xue et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans
- (2014) Kacper A. Wojtal et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Crohn's Disease: Loss of Tolerance or a Disorder of Autophagy?
- (2014) Marianne R. Spalinger et al. DIGESTIVE DISEASES
- HIF Transcription Factors, Inflammation, and Immunity
- (2014) Asis Palazon et al. IMMUNITY
- Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells
- (2014) Yan-mei Zou et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases
- (2014) Holger K. Eltzschig et al. NATURE REVIEWS DRUG DISCOVERY
- Autophagy and hypoxia in colonic adenomas related to aggressive features
- (2013) A. Giatromanolaki et al. Colorectal Disease
- High altitude journeys and flights are associated with an increased risk of flares in inflammatory bowel disease patients
- (2013) Stephan R. Vavricka et al. Journal of Crohns & Colitis
- Characterisation of enterocolitis in the piroxicam-accelerated interleukin-10 knock out mouse — A model mimicking inflammatory bowel disease
- (2013) Kristine Holgersen et al. Journal of Crohns & Colitis
- Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis
- (2013) S Keely et al. Mucosal Immunology
- Quantitative Phenotyping of Inflammatory Bowel Disease in the IL-10-deficient Mouse by Use of Noninvasive Magnetic Resonance Imaging
- (2012) Svenja Michael et al. INFLAMMATORY BOWEL DISEASES
- Inflammasome-Independent NLRP3 Augments TGF- Signaling in Kidney Epithelium
- (2012) W. Wang et al. JOURNAL OF IMMUNOLOGY
- Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
- (2012) Chong-Shan Shi et al. NATURE IMMUNOLOGY
- Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
- (2012) E. T. Clambey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO
- (2012) Yuri Shibata et al. Nature Communications
- Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery
- (2011) Sean P. Colgan et al. Annual Review of Physiology
- Interaction between Susceptibility and Environment: Examples from the Digestive Tract
- (2011) Gerhard Rogler DIGESTIVE DISEASES
- Autophagy, Microbial Sensing, Endoplasmic Reticulum Stress, and Epithelial Function in Inflammatory Bowel Disease
- (2011) Arthur Kaser et al. GASTROENTEROLOGY
- Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice
- (2011) Matthew Taylor et al. GASTROENTEROLOGY
- Genetics and pathogenesis of inflammatory bowel disease
- (2011) Bernard Khor et al. NATURE
- Inflammasome-Independent Modulation of Cytokine Response by Autophagy in Human Cells
- (2011) Tania O. Crişan et al. PLoS One
- The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
- (2010) K. Schroder et al. SCIENCE
- Cyclooxygenase-2 and Hypoxia-Inducible Factor-1α protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis
- (2009) Francesco Mariani et al. CANCER LETTERS
- DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival
- (2009) Timothy R. Peterson et al. CELL
- ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
- (2009) Ian G. Ganley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
- (2009) Nao Hosokawa et al. MOLECULAR BIOLOGY OF THE CELL
- The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
- (2009) Luigi Franchi et al. NATURE IMMUNOLOGY
- Enterocyte Shedding and Epithelial Lining Repair Following Ischemia of the Human Small Intestine Attenuate Inflammation
- (2009) Robert A. Matthijsen et al. PLoS One
- The Role of Stress in the Development and Clinical Course of Inflammatory Bowel Disease: Epidemiological Evidence
- (2008) Robert Maunder et al. CURRENT MOLECULAR MEDICINE
- Structural Basis for Sorting Mechanism of p62 in Selective Autophagy
- (2008) Yoshinobu Ichimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
- (2008) Alexandra-Chloé Villani et al. NATURE GENETICS
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
- The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis
- (2007) Eoin P. Cummins et al. GASTROENTEROLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started