The Crohn’s Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy

Title
The Crohn’s Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy
Authors
Keywords
IRGM, Irgm1, NLRP3, ASC, autophagy, p62, inflammasome, Crohn’s disease, inflammatory disorders, autoimmunity, inflammatory bowel diseases
Journal
MOLECULAR CELL
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2019-01-04
DOI
10.1016/j.molcel.2018.11.018

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