Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles

Kicking Genomic Profiling to the Curb: How Re-wiring the Phosphoproteome Can Explain Treatment Resistance in Glioma

(2016) Fred C. Lam et al.   CANCER CELL

OTX015 (MK-8628), a novel BET inhibitor, displaysin vitroandin vivoantitumor effects alone and in combination with conventional therapies in glioblastoma models

(2016) Caroline Berenguer-Daizé et al.   INTERNATIONAL JOURNAL OF CANCER

Liposome-based glioma targeted drug delivery enabled by stable peptide ligands

(2015) Xiaoli Wei et al.   JOURNAL OF CONTROLLED RELEASE

Therapeutic strategies to improve drug delivery across the blood-brain barrier

(2015) Tej D. Azad et al.   Neurosurgical Focus

Novel delivery methods bypassing the blood-brain and blood-tumor barriers

(2015) Benjamin K. Hendricks et al.   Neurosurgical Focus

Epigenetic drugs against cancer: an evolving landscape

(2014) Antonella Di Costanzo et al.   ARCHIVES OF TOXICOLOGY

A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways

(2014) S. W. Morton et al.   Science Signaling

Transferrin Receptor 2 Is Frequently and Highly Expressed in Glioblastomas

(2014) Alessia Calzolari et al.   Translational Oncology

A dual-targeting liposome conjugated with transferrin and arginine-glycine-aspartic acid peptide for glioma-targeting therapy

(2014) LI QIN et al.   Oncology Letters

Inducible In Vivo Silencing of Brd4 Identifies Potential Toxicities of Sustained BET Protein Inhibition

(2014) Jessica E. Bolden et al.   Cell Reports

Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood–Brain Barrier

(2014) Julia Georgieva et al.   Pharmaceutics

Transferrin-conjugated magnetic silica PLGA nanoparticles loaded with doxorubicin and paclitaxel for brain glioma treatment

(2013) Yanna Cui et al.   BIOMATERIALS

Transferrin-Modified Doxorubicin-Loaded Biodegradable Nanoparticles Exhibit Enhanced Efficacy in Treating Brain Glioma-Bearing Rats

(2013) Guodong Liu et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Immunogenicity and toxicity of transferrin receptor-targeted hybrid peptide as a potent anticancer agent

(2013) Megumi Kawamoto et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma

(2013) Z. Cheng et al.   CLINICAL CANCER RESEARCH

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

(2013) Scott R. Floyd et al.   NATURE

Small-Molecule Inhibition of BRDT for Male Contraception

(2012) Martin M. Matzuk et al.   CELL

Transferrin-Modified c[RGDfK]-Paclitaxel Loaded Hybrid Micelle for Sequential Blood-Brain Barrier Penetration and Glioma Targeting Therapy

(2012) Pengcheng Zhang et al.   MOLECULAR PHARMACEUTICS

Nanotechnology—novel therapeutics for CNS disorders

(2012) Maya Srikanth et al.   Nature Reviews Neurology

Modern methods for delivery of drugs across the blood–brain barrier

(2011) Yan Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Transport of drugs across the blood–brain barrier by nanoparticles

(2011) Stefanie Wohlfart et al.   JOURNAL OF CONTROLLED RELEASE

Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting

(2010) Shyh-Dar Li et al.   JOURNAL OF CONTROLLED RELEASE

Mediating Tumor Targeting Efficiency of Nanoparticles Through Design

(2009) Steven D. Perrault et al.   NANO LETTERS