Comparison of Lentiviral and Sleeping Beauty Mediated αβ T Cell Receptor Gene Transfer

Sleeping Beauty System to Redirect T-cell Specificity for Human Applications

(2013) Sourindra N. Maiti et al.   JOURNAL OF IMMUNOTHERAPY

Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells

(2012) J. Scholler et al.   Science Translational Medicine

Bioinformatic Clonality Analysis of Next-Generation Sequencing-Derived Viral Vector Integration Sites

(2012) Anne Arens et al.   Human Gene Therapy Methods

Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination

(2011) C. Pospori et al.   BLOOD

The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor

(2011) Z Jin et al.   GENE THERAPY

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor

(2010) B. Jena et al.   BLOOD

Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer

(2010) M Perro et al.   GENE THERAPY

Unexpectedly High Copy Number of Random Integration but Low Frequency of Persistent Expression of the Sleeping Beauty Transposase After Trans Delivery in Primary Human T Cells

(2010) Xin Huang et al.   HUMAN GENE THERAPY

Gene Transfer Efficiency and Genome-Wide Integration Profiling of Sleeping Beauty, Tol2, and PiggyBac Transposons in Human Primary T Cells

(2010) Xin Huang et al.   MOLECULAR THERAPY

Development of a Wilms' tumor antigen-specific T-cell receptor for clinical trials: engineered patient's T cells can eliminate autologous leukemia blasts in NOD/SCID mice

(2009) S.-A. Xue et al.   HAEMATOLOGICA

Moving Gene Therapy Forward with Mobile DNA

(2009) Thierry VandenDriessche et al.   HUMAN GENE THERAPY

Sleeping Beauty Transposition From Nonintegrating Lentivirus

(2009) Conrad A Vink et al.   MOLECULAR THERAPY

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

(2009) Lajos Mátés et al.   NATURE GENETICS

Redirecting Specificity of T-Cell Populations For CD19 Using the Sleeping Beauty System

(2008) H. Singh et al.   CANCER RESEARCH