In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers

Synthesis and application of poly(ethylene glycol)-co-poly(β-amino ester) copolymers for small cell lung cancer gene therapy

(2016) Jayoung Kim et al.   Acta Biomaterialia

Nanoparticle-mediated transcriptional modification enhances neuronal differentiation of human neural stem cells following transplantation in rat brain

(2016) Xiaowei Li et al.   BIOMATERIALS

Gene Therapy: The View from NCATS

(2016) Philip J. Brooks et al.   HUMAN GENE THERAPY

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

(2016) Partow Kebriaei et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors

(2016) R Monjezi et al.   LEUKEMIA

Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform

(2016) Chiara F. Magnani et al.   Oncotarget

Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo

(2015) Antonella Mangraviti et al.   ACS Nano

CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia

(2015) S. L. Maude et al.   BLOOD

Synthetic biology approaches to engineer T cells

(2015) Chia-Yung Wu et al.   CURRENT OPINION IN IMMUNOLOGY

CAR therapy: the CD19 paradigm

(2015) Michel Sadelain   JOURNAL OF CLINICAL INVESTIGATION

Large-scale Clinical-grade Retroviral Vector Production in a Fixed-Bed Bioreactor

(2015) Xiuyan Wang et al.   JOURNAL OF IMMUNOTHERAPY

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

(2015) Karoline B Kuchenbaecker et al.   NATURE GENETICS

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma

(2015) Laura A. Johnson et al.   Science Translational Medicine

Minicircle DNA vectors for gene therapy: advances and applications

(2014) Vítor Gaspar et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

A Novel Chimeric Antigen Receptor Against Prostate Stem Cell Antigen Mediates Tumor Destruction in a Humanized Mouse Model of Pancreatic Cancer

(2014) Daniel Abate-Daga et al.   HUMAN GENE THERAPY

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

(2014) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumour heterogeneity and cancer cell plasticity

(2013) Corbin E. Meacham et al.   NATURE

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

(2013) Stephan A. Grupp et al.   NEW ENGLAND JOURNAL OF MEDICINE

CD19 CAR-Targeted T Cells Induce Long-Term Remission and B Cell Aplasia in an Immunocompetent Mouse Model of B Cell Acute Lymphoblastic Leukemia

(2013) Marco L. Davila et al.   PLoS One

Mimicking cellular transport mechanism in stem cells through endosomal escape of new peptide-coated quantum dots

(2013) Karthikeyan Narayanan et al.   Scientific Reports

Evaluation of Long-term Transgene Expression in piggyBac-Modified Human T Lymphocytes

(2012) Yozo Nakazawa et al.   JOURNAL OF IMMUNOTHERAPY

A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon

(2012) Erin R Burnight et al.   Molecular Therapy-Nucleic Acids

Cell transfer immunotherapy for metastatic solid cancer—what clinicians need to know

(2011) Steven A. Rosenberg   Nature Reviews Clinical Oncology

Monitoring the Efficacy of Adoptively Transferred Prostate Cancer-Targeted Human T Lymphocytes with PET and Bioluminescence Imaging

(2008) K. Dobrenkov et al.   JOURNAL OF NUCLEAR MEDICINE