Nerolidol Attenuates Oxidative Stress, Inflammation, and Apoptosis by Modulating Nrf2/MAPK Signaling Pathways in Doxorubicin-Induced Acute Cardiotoxicity in Rats

Liposomal Resveratrol and/or Carvedilol Attenuate Doxorubicin-Induced Cardiotoxicity by Modulating Inflammation, Oxidative Stress and S100A1 in Rats

(2020) Abeer M. Alanazi et al.   Antioxidants

Nerolidol Mitigates Colonic Inflammation: An Experimental Study Using both In Vivo and In Vitro Models

(2020) Vishnu Raj et al.   Nutrients

Resolvin E1 protects against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress, autophagy and apoptosis by targeting AKT/mTOR signaling

(2020) Jishou Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Nerolidol protects the liver against cyclophosphamide‐induced hepatic inflammation, apoptosis, and fibrosis via modulation of Nrf2, NF‐κB p65, and caspase‐3 signaling molecules in Swiss albino mice

(2020) Ashif Iqubal et al.   BIOFACTORS

New insights into the activities and toxicities of the old anticancer drug doxorubicin

(2020) Sabina Y. van der Zanden et al.   FEBS Journal

Management of Cardiac Toxicity Induced by Chemotherapy

(2020) Dario Trapani et al.   Journal of Clinical Medicine

Endoplasmic reticulum stress in doxorubicin-induced cardiotoxicity may be therapeutically targeted by natural and chemical compounds: A review

(2020) Fatemeh Yarmohammadi et al.   PHARMACOLOGICAL RESEARCH

Wheat phenolics suppress doxorubicin-induced cardiotoxicity via inhibition of oxidative stress, MAP kinase activation, NF-κB pathway, PI3K/Akt/mTOR impairment, and cardiac apoptosis

(2019) Ranabir Sahu et al.   FOOD AND CHEMICAL TOXICOLOGY

β-Caryophyllene, a natural bicyclic sesquiterpene attenuates doxorubicin-induced chronic cardiotoxicity via activation of myocardial cannabinoid type-2 (CB2) receptors in rats

(2019) M.F. Nagoor Meeran et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cardioprotective Potential of Plant-Derived Molecules: A Scientific and Medicinal Approach

(2019) Syed Muhammad Ali Shah et al.   Dose-Response

Preventive effect of nerolidol on isoproterenol induced myocardial damage in Wistar rats: Evidences from biochemical and histopathological studies

(2019) Loordhurani Asaikumar et al.   DRUG DEVELOPMENT RESEARCH

β-caryophyllene, a dietary phytocannabinoid attenuates oxidative stress, inflammation, apoptosis and prevents structural alterations of the myocardium against doxorubicin-induced acute cardiotoxicity in rats: An in vitro and in vivo study

(2019) Hasan Al-Taee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nerolidol attenuates cyclophosphamide-induced cardiac inflammation, apoptosis and fibrosis in Swiss Albino mice

(2019) Ashif Iqubal et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nerolidol ameliorates cyclophosphamide-induced oxidative stress, neuroinflammation and cognitive dysfunction: Plausible role of Nrf2 and NF- κB

(2019) Ashif Iqubal et al.   LIFE SCIENCES

Nerolidol Suppresses the Inflammatory Response during Lipopolysaccharide-Induced Acute Lung Injury via the Modulation of Antioxidant Enzymes and the AMPK/Nrf-2/HO-1 Pathway

(2019) Yung-Lun Ni et al.   Oxidative Medicine and Cellular Longevity

Cardamonin protects against doxorubicin-induced cardiotoxicity in mice by restraining oxidative stress and inflammation associated with Nrf2 signaling

(2019) Wang Qi et al.   BIOMEDICINE & PHARMACOTHERAPY

Luteolin-mediated PI3K/AKT/Nrf2 signaling pathway ameliorates inorganic mercury-induced cardiac injury

(2018) Ruiqi Baiyun et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Risk-benefit of dexrazoxane for preventing anthracycline-related cardiotoxicity: re-evaluating the European labeling

(2018) Peter Reichardt et al.   Future Oncology

Diethyl Blechnic, a Novel Natural Product Isolated from Salvia miltiorrhiza Bunge, Inhibits Doxorubicin-Induced Apoptosis by Inhibiting ROS and Activating JNK1/2

(2018) Jie Yu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The aroma volatile repertoire in strawberry fruit: a review

(2018) Jia-wei Yan et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products

(2018) Jie Yu et al.   PHYTOMEDICINE

Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells

(2018) Ming-Xing Zhou et al.   Redox Biology

Ginsenoside Rg1 Prevents Doxorubicin-Induced Cardiotoxicity through the Inhibition of Autophagy and Endoplasmic Reticulum Stress in Mice

(2018) Zhi-Meng Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pristimerin protects against doxorubicin-induced cardiotoxicity and fibrosis through modulation of Nrf2 and MAPK/NF-kB signaling pathways

(2018) Dina S. El-Agamy et al.   Cancer Management and Research

Formation of ( E )-nerolidol in tea ( Camellia sinensis ) leaves exposed to multiple stresses during tea manufacturing

(2017) Ying Zhou et al.   FOOD CHEMISTRY

Protective effect of zerumbone reduces lipopolysaccharide-induced acute lung injury via antioxidative enzymes and Nrf2/HO-1 pathway

(2017) Wai-Shing Leung et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines

(2017) Martin Ambrož et al.   MOLECULES

Negative inotropism of terpenes on guinea pig left atrium: structure-activity relationships

(2017) Carla M. L. Vasconcelos et al.   NATURAL PRODUCT RESEARCH

Cardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway

(2017) Shudong Wang et al.   Cell Death & Disease

Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts

(2017) Lizhen Huang et al.   Scientific Reports

Activation of apoptosis signalling pathways by reactive oxygen species

(2016) Maureen Redza-Dutordoir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neuroprotective effect of nerolidol against neuroinflammation and oxidative stress induced by rotenone

(2016) Hayate Javed et al.   BMC NEUROSCIENCE

The Cardio-oncology Program: A Multidisciplinary Approach to the Care of Cancer Patients With Cardiovascular Disease

(2016) Sarah Parent et al.   CANADIAN JOURNAL OF CARDIOLOGY

Baicalein alleviates doxorubicin-induced cardiotoxicity via suppression of myocardial oxidative stress and apoptosis in mice

(2016) Bidya Dhar Sahu et al.   LIFE SCIENCES

Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities

(2016) Weng-Keong Chan et al.   MOLECULES

Cardioprotective Potentials of Plant-Derived Small Molecules against Doxorubicin Associated Cardiotoxicity

(2016) Shreesh Ojha et al.   Oxidative Medicine and Cellular Longevity

Role of Drug Metabolism in the Cytotoxicity and Clinical Efficacy of Anthracyclines

(2015) Derek Edwardson et al.   CURRENT DRUG METABOLISM

Nerolidol exhibits antinociceptive and anti-inflammatory activity: involvement of the GABAergic system and proinflammatory cytokines

(2015) Diogo V. Fonsêca et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Protective Effects of 7-Hydroxycoumarin on Dyslipidemia and Cardiac Hypertrophy in Isoproterenol-Induced Myocardial Infarction in Rats

(2015) Govindan Sangaran Jagadeesh et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells

(2015) Martin Ambrož et al.   MOLECULES

Persistent γH2AX: A promising molecular marker of DNA damage and aging

(2015) Mohammad Sabbir Siddiqui et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Thymol attenuates altered lipid metabolism in β-adrenergic agonist induced myocardial infarcted rats by inhibiting tachycardia, altered electrocardiogram, apoptosis and cardiac hypertrophy

(2015) Mohamed Fizur Nagoor Meeran et al.   Journal of Functional Foods

Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis

(2014) Eman M. Mantawy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Multifunctional pentacyclic triterpenoids as adjuvants in cancer chemotherapy: a review

(2014) Sarika M. Kamble et al.   RSC Advances

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB in LPS-stimulated RAW264.7 cells and mouse liver

(2013) Dae Hyun Kim et al.   Journal of Ginseng Research

Effect of ursolic acid treatment on apoptosis and DNA damage in isoproterenol-induced myocardial infarction

(2012) Thangaiyan Radhiga et al.   BIOCHIMIE

Taurine suppresses doxorubicin-triggered oxidative stress and cardiac apoptosis in rat via up-regulation of PI3-K/Akt and inhibition of p53, p38-JNK

(2011) Joydeep Das et al.   BIOCHEMICAL PHARMACOLOGY

Changes in mitochondrial redox state, membrane potential and calcium precede mitochondrial dysfunction in doxorubicin-induced cell death

(2011) Andrey V. Kuznetsov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Chromatin dynamics and the repair of DNA double strand breaks

(2011) Ye Xu et al.   CELL CYCLE

Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis)

(2011) Sol A. Green et al.   JOURNAL OF EXPERIMENTAL BOTANY

Doxorubicin: The Good, the Bad and the Ugly Effect

(2009) Cristina Carvalho et al.   CURRENT MEDICINAL CHEMISTRY