Chromatin dynamics and the repair of DNA double strand breaks

High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

(2010) Jason S Iacovoni et al.   EMBO JOURNAL

Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway

(2010) Xiaofeng Jiang et al.   FEBS LETTERS

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

(2010) Ye Xu et al.   JOURNAL OF CELL BIOLOGY

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

(2010) Angela T. Noon et al.   NATURE CELL BIOLOGY

DNA resection in eukaryotes: deciding how to fix the break

(2010) Pablo Huertas   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Biology of Chromatin Remodeling Complexes

(2009) Cedric R. Clapier et al.   Annual Review of Biochemistry

The impact of heterochromatin on DSB repair

(2009) Aaron A. Goodarzi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Histone acetylation: truth of consequences?This paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Jennifer K. Choi et al.   Biochemistry and Cell Biology

Connection between histone H2A variants and chromatin remodeling complexesThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Mohammed Altaf et al.   Biochemistry and Cell Biology

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

Heterochromatin protein 1 is recruited to various types of DNA damage

(2009) Martijn S. Luijsterburg et al.   JOURNAL OF CELL BIOLOGY

Formation of Dynamic γ-H2AX Domains along Broken DNA Strands Is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin

(2009) Velibor Savic et al.   MOLECULAR CELL

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress

(2009) Joanna R. Morris et al.   NATURE

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

(2009) Yaron Galanty et al.   NATURE

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

(2009) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60

(2009) Yingli Sun et al.   NATURE CELL BIOLOGY

The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways

(2009) L Mattera et al.   ONCOGENE

Chromatin dynamics during repair of chromosomal DNA double-strand breaks

(2009) Manisha Sinha et al.   Epigenomics

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

Chromatin domains in higher eukaryotes: insights from genome-wide mapping studies

(2008) Elzo de Wit et al.   CHROMOSOMA

Epigenetic regulation of heterochromatic DNA stability

(2008) Jamy C Peng et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

(2008) J Ross Chapman et al.   EMBO REPORTS

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin

(2008) Fredrik Melander et al.   JOURNAL OF CELL BIOLOGY

Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin

(2008) Christoph Spycher et al.   JOURNAL OF CELL BIOLOGY

30 nm Chromatin Fibre Decompaction Requires both H4-K16 Acetylation and Linker Histone Eviction

(2008) Philip J.J. Robinson et al.   JOURNAL OF MOLECULAR BIOLOGY

Human Rvb1/Tip49 Is Required for the Histone Acetyltransferase Activity of Tip60/NuA4 and for the Downregulation of Phosphorylation on H2AX after DNA Damage

(2008) S. Jha et al.   MOLECULAR AND CELLULAR BIOLOGY

Eaf1 Is the Platform for NuA4 Molecular Assembly That Evolutionarily Links Chromatin Acetylation to ATP-Dependent Exchange of Histone H2A Variants

(2008) A. Auger et al.   MOLECULAR AND CELLULAR BIOLOGY

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

HP1-β mobilization promotes chromatin changes that initiate the DNA damage response

(2008) Nabieh Ayoub et al.   NATURE

Structural insights into human KAP1 PHD finger–bromodomain and its role in gene silencing

(2008) Lei Zeng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc

(2008) K. A. Tworkowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA