Sialic Acids as Receptors for Pathogens

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung

(2021) Hin Chu et al.   Nature Communications

The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition

(2021) Núria Ros-Rocher et al.   Open Biology

Lack of support for Deuterostomia prompts reinterpretation of the first Bilateria

(2021) Paschalia Kapli et al.   Science Advances

A sialic acid-binding protein SABP1 facilitated host cell attachment and invasion by Toxoplasma gondii

(2020) Mengen Xing et al.   JOURNAL OF INFECTIOUS DISEASES

IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era

(2020) Bui Quang Minh et al.   MOLECULAR BIOLOGY AND EVOLUTION

The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication

(2020) Tri Nguyen et al.   PLoS Pathogens

The Putative TCP-1 Chaperonin Is an Important Player Involved in Sialic Acid-Dependent Host Cell Invasion by Toxoplasma gondii

(2020) Na Yang et al.   Frontiers in Microbiology

SV40 and human mesothelioma

(2020) Michele Carbone et al.   Translational Lung Cancer Research

Averting transmission: A pivotal target to manage amoebiasis

(2020) Aadish Rawat et al.   Chemical Biology & Drug Design

Diversity of sialidases found in the human body – A review

(2020) Sabina Lipničanová et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Pseudomonas aeruginosa Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing

(2020) Roland Thuenauer et al.   mBio

Coronavirus disease 2019 (COVID-19): A literature review

(2020) Harapan Harapan et al.   Journal of Infection and Public Health

The landscape of extrapulmonary manifestations of human parainfluenza viruses: A systematic narrative review

(2020) Mohammad Farahmand et al.   MICROBIOLOGY AND IMMUNOLOGY

Topology-dependent asymmetry in systematic errors affects phylogenetic placement of Ctenophora and Xenacoelomorpha

(2020) Paschalia Kapli et al.   Science Advances

The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management

(2019) Khalid O. Alfarouk et al.   Frontiers in Oncology

Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A

(2019) Ruben J. G. Hulswit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nontypeable Haemophilus influenzae Has Evolved Preferential Use of N-Acetylneuraminic Acid as a Host Adaptation

(2019) Preston S. K. Ng et al.   mBio

Mechanisms of Human Innate Immune Evasion by Toxoplasma gondii

(2019) Tatiane S. Lima et al.   Frontiers in Cellular and Infection Microbiology

Integrin αvβ6 mediates epithelial-mesenchymal transition in human bronchial epithelial cells induced by lipopolysaccharides of Pseudomonas aeruginosa via TGF-β1-Smad2/3 signaling pathway

(2019) Weiming Liu et al.   FOLIA MICROBIOLOGICA

Erythrocyte glycophorins as receptors for Plasmodium merozoites

(2019) Ewa Jaskiewicz et al.   Parasites & Vectors

Absence of Neu5Gc and Presence of Anti-Neu5Gc Antibodies in Humans—An Evolutionary Perspective

(2019) Meghan O. Altman et al.   Frontiers in Immunology

Association Between Simian Virus 40 and Human Tumors

(2019) John Charles Rotondo et al.   Frontiers in Oncology

Complex Multilevel Control of Hemolysin Production by Uropathogenic Escherichia coli

(2019) Nguyen Thi Khanh Nhu et al.   mBio

Host Invasion by Pathogenic Amoebae: Epithelial Disruption by Parasite Proteins

(2019) Betanzos et al.   Genes

Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand

(2019) William R. Proto et al.   Nature Communications

Post-Glycosylation Modification of Sialic Acid and Its Role in Virus Pathogenesis

(2019) Park   Vaccines

Pseudomonas aeruginosa uses multiple receptors for adherence to laminin during infection of the respiratory tract and skin wounds

(2019) Magnus Paulsson et al.   Scientific Reports

Role of different receptors and actin filaments on Salmonella Typhimurium invasion in chicken macrophages

(2018) Deepthi Kappala et al.   IMMUNOBIOLOGY

Chagas disease

(2018) José A Pérez-Molina et al.   LANCET

The Gerbich blood group system: old knowledge, new importance

(2018) Ewa Jaskiewicz et al.   TRANSFUSION MEDICINE REVIEWS

Evolution of sialic acids: Implications in xenotransplant biology

(2018) Anu Paul et al.   XENOTRANSPLANTATION

Helicobacter pylori SabA binding gangliosides of human stomach

(2018) John Benktander et al.   Virulence

H3N2 influenza viruses in humans: Viral mechanisms, evolution, and evaluation

(2018) James D. Allen et al.   Human Vaccines & Immunotherapeutics

Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera

(2018) Frederico Alisson-Silva et al.   PLoS Pathogens

Toxoplasma gondii

(2018) Joshua A. Kochanowsky et al.   CURRENT BIOLOGY

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Inhibition of sialidase activity as a therapeutic approach

(2018) Victor Yu Glanz et al.   Drug Design Development and Therapy

Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc

(2017) Sateesh Peri et al.   Genome Biology and Evolution

Haemophilus Protein F Orthologs of Pathogens Infecting the Airways: Exploiting Host Laminin at Heparin-Binding Sites for Maximal Adherence to Epithelial Cells

(2017) Yu-Ching Su et al.   JOURNAL OF INFECTIOUS DISEASES

ModelFinder: fast model selection for accurate phylogenetic estimates

(2017) Subha Kalyaanamoorthy et al.   NATURE METHODS

Plasmodium reichenowi EBA-140 merozoite ligand binds to glycophorin D on chimpanzee red blood cells, shedding new light on origins of Plasmodium falciparum

(2017) Agata Zerka et al.   Parasites & Vectors

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein

(2017) Wentao Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autotransporter Adhesins in Escherichia coli Pathogenesis

(2017) Julieanne L. Vo et al.   PROTEOMICS

Systemic effects of Subtilase cytotoxin produced by Escherichia coli O113:H21

(2017) E. Abril Seyahian et al.   TOXICON

Novel Influenza D virus: Epidemiology, pathology, evolution and biological characteristics

(2017) Shuo Su et al.   Virulence

Evolution of host adaptation in the Salmonella typhoid toxin

(2017) Xiang Gao et al.   Nature Microbiology

Conformational divergence in the HA-33/HA-17 trimer of serotype C and D botulinum toxin complex

(2016) Yoshimasa Sagane et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sialidases from gut bacteria: a mini-review

(2016) N. Juge et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Biosynthetic and synthetic access to amino sugars

(2016) Kornelia Skarbek et al.   CARBOHYDRATE RESEARCH

Free Sialic Acid Acts as a Signal That Promotes Streptococcus pneumoniae Invasion of Nasal Tissue and Nonhematogenous Invasion of the Central Nervous System

(2016) Brandon L. Hatcher et al.   INFECTION AND IMMUNITY

Community-acquired Haemophilus influenzae pneumonia – New insights from the CAPNETZ study

(2016) Christina Forstner et al.   JOURNAL OF INFECTION

Botulism

(2016) M. A. Carrillo-Marquez   PEDIATRICS IN REVIEW

Parainfluenza Virus Infection

(2016) Angela Branche et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of Sialic Acid Modifications on Virus Binding and Infection

(2016) Brian R. Wasik et al.   TRENDS IN MICROBIOLOGY

Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

(2016) Selasi Dankwa et al.   Nature Communications

Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

(2016) Song Lin Chua et al.   Nature Communications

The interplay ofEscherichia coliO157:H7 and commensalE. coli: the importance of strain-level identification

(2016) Hillary M. Figler et al.   Expert Review of Gastroenterology & Hepatology

The distribution pattern of α2,3- and α2,6-linked sialic acids affects host cell preference in Toxoplasma gondii

(2015) Minami Baba et al.   EXPERIMENTAL PARASITOLOGY

Clostridium botulinumtype C hemagglutinin affects the morphology and viability of cultured mammalian cells via binding to the ganglioside GM3

(2015) Yo Sugawara et al.   FEBS Journal

Influenza B viruses: not to be discounted

(2015) Carolien E van de Sandt et al.   Future Microbiology

Trypanosoma cruzitrans-Sialidase Prevents Elicitation of Th1 Cell Response via Interleukin 10 and Downregulates Th1 Effector Cells

(2015) Pablo Ruiz Díaz et al.   INFECTION AND IMMUNITY

Human Coronavirus HKU1 Spike Protein UsesO-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme

(2015) Xingchuan Huang et al.   JOURNAL OF VIROLOGY

Hemichordate genomes and deuterostome origins

(2015) Oleg Simakov et al.   NATURE

Infant Botulism: Review and Clinical Update

(2015) Laura K. Rosow et al.   PEDIATRIC NEUROLOGY

Two-component systems and toxinogenesis regulation in Clostridium botulinum

(2015) Chloé Connan et al.   RESEARCH IN MICROBIOLOGY

Hemagglutinin-esterase-fusion (HEF) protein of influenza C virus

(2015) Mingyang Wang et al.   Protein & Cell

The structures of glycophorin C N-glycans, a putative component of the GPC receptor site for Plasmodium falciparum EBA-140 ligand

(2015) David J Ashline et al.   GLYCOBIOLOGY

The Baculovirus-Expressed Binding Region of Plasmodium falciparum EBA-140 Ligand and Its Glycophorin C Binding Specificity

(2015) Joanna Rydzak et al.   PLoS One

Regulation of Virulence ofEntamoeba histolytica

(2014) Chelsea Marie et al.   Annual Review of Microbiology

Role of receptor binding specificity in influenza A virus transmission and pathogenesis

(2014) M. de Graaf et al.   EMBO JOURNAL

N-Glycolylneuraminic Acid on Human Epithelial Cells Prevents Entry of Influenza A Viruses That Possess N-Glycolylneuraminic Acid Binding Ability

(2014) T. Takahashi et al.   JOURNAL OF VIROLOGY

Critical Glycosylated Residues in Exon Three of Erythrocyte Glycophorin A Engage Plasmodium falciparum EBA-175 and Define Receptor Specificity

(2014) N. D. Salinas et al.   mBio

The hierarchy quorum sensing network in Pseudomonas aeruginosa

(2014) Jasmine Lee et al.   Protein & Cell

Same species, different diseases: how and why typhoidal and non-typhoidal Salmonella enterica serovars differ

(2014) Ohad Gal-Mor et al.   Frontiers in Microbiology

Sialic acid-dependent attachment of mucins from three mouse strains to Entamoeba histolytica

(2013) Kentaro Kato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

α2-3 Sialic acid glycoconjugate loss and its effect on infection with Toxoplasma parasites

(2013) Yoshifumi Nishikawa et al.   EXPERIMENTAL PARASITOLOGY

Cholera: pathophysiology and emerging therapeutic targets

(2013) Chatchai Muanprasat et al.   Future Medicinal Chemistry

Internalization and Trafficking of Nontypeable Haemophilus influenzae in Human Respiratory Epithelial Cells and Roles of IgA1 Proteases for Optimal Invasion and Persistence

(2013) Cara F. Clementi et al.   INFECTION AND IMMUNITY

Relative Contributions of Lipooligosaccharide Inner and Outer Core Modifications to Nontypeable Haemophilus influenzae Pathogenesis

(2013) Pau Morey et al.   INFECTION AND IMMUNITY

Biochemical Analysis of thePlasmodium falciparumErythrocyte-binding Antigen-175 (EBA175)-Glycophorin-A Interaction

(2013) Madushi Wanaguru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis for Sialic Acid-dependent Receptor Recognition by thePlasmodium falciparumInvasion Protein Erythrocyte-binding Antigen-140/BAEBL

(2013) Brian M. Malpede et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RH5-Basigin interaction plays a major role in the host tropism of Plasmodium falciparum

(2013) M. Wanaguru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pneumococcus: Epidemiology, Microbiology, and Pathogenesis

(2013) B. Henriques-Normark et al.   Cold Spring Harbor Perspectives in Medicine

Catalytic preference of Salmonella typhimurium LT2 sialidase for N -acetylneuraminic acid residues over N -glycolylneuraminic acid residues

(2013) Akira Minami et al.   FEBS Open Bio

Carbohydrate recognition mechanism of HA70 fromClostridium botulinumdeduced from X-ray structures in complexes with sialylated oligosaccharides

(2012) Satoshi Yamashita et al.   FEBS LETTERS

Mammalian sialidases: Physiological and pathological roles in cellular functions

(2012) T. Miyagi et al.   GLYCOBIOLOGY

Crystal and Solution Structures ofPlasmodium falciparumErythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion

(2012) Daniel H. Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Revised Classification of Eukaryotes

(2012) Sina M. Adl et al.   JOURNAL OF EUKARYOTIC MICROBIOLOGY

Invasive Haemophilus influenzae in the United States, 1999–2008: Epidemiology and outcomes

(2012) Daniel J. Livorsi et al.   JOURNAL OF INFECTION

Haemophilus influenzae Protein F Mediates Binding to Laminin and Human Pulmonary Epithelial Cells

(2012) Farshid Jalalvand et al.   JOURNAL OF INFECTIOUS DISEASES

Pseudomonas aeruginosa Pili and Flagella Mediate Distinct Binding and Signaling Events at the Apical and Basolateral Surface of Airway Epithelium

(2012) Iwona Bucior et al.   PLoS Pathogens

Sialic acid: a sweet swing between mammalian host and Trypanosoma cruzi

(2012) Leonardo Freire-de-Lima et al.   Frontiers in Immunology

Chemistry of Ni2+in Urease: Sensing, Trafficking, and Catalysis

(2011) Barbara Zambelli et al.   ACCOUNTS OF CHEMICAL RESEARCH

Presenting your structures: theCCP4mgmolecular-graphics software

(2011) S. McNicholas et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and applications of bacterial sialidases

(2011) Seonghun Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Trans-sialidase and mucins of Trypanosoma cruzi: an important interplay for the parasite

(2011) M. Eugenia Giorgi et al.   CARBOHYDRATE RESEARCH

Molecular interactions and signaling mechanisms during erythrocyte invasion by malaria parasites

(2011) Deepak Gaur et al.   CURRENT OPINION IN MICROBIOLOGY

Viruses and sialic acids: rules of engagement

(2011) Ursula Neu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Influenza neuraminidase

(2011) Gillian M. Air   Influenza and Other Respiratory Viruses

Haemophilus influenzae Protein E Binds to the Extracellular Matrix by Concurrently Interacting With Laminin and Vitronectin

(2011) Teresia Hallström et al.   JOURNAL OF INFECTIOUS DISEASES

Exposure of Thomsen-Friedenreich antigen in Streptococcus pneumoniae infection is dependent on pneumococcal neuraminidase A

(2011) Mamie T. Coats et al.   MICROBIAL PATHOGENESIS

C-type natriuretic peptide modulates quorum sensing molecule and toxin production in Pseudomonas aeruginosa

(2011) A.-S. Blier et al.   MICROBIOLOGY-SGM

Sexual selection by female immunity against paternal antigens can fix loss of function alleles

(2011) D. Ghaderi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudomonas aeruginosa: all roads lead to resistance

(2011) Elena B.M. Breidenstein et al.   TRENDS IN MICROBIOLOGY

Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparum

(2011) Wai-Hong Tham et al.   TRENDS IN PARASITOLOGY

The Global Burden of NontyphoidalSalmonellaGastroenteritis

(2010) Shannon E. Majowicz et al.   CLINICAL INFECTIOUS DISEASES

Streptococcus pneumoniae: virulence factors and variation

(2010) A.M. Mitchell et al.   CLINICAL MICROBIOLOGY AND INFECTION

Sialic acids: Key determinants for invasion by the Apicomplexa

(2010) Nikolas Friedrich et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Influenza Hemagglutinin and Neuraminidase Membrane Glycoproteins

(2010) Steven J. Gamblin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acidN-glycolylneuraminic acid

(2010) Rachel E. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Origin of the human malaria parasite Plasmodium falciparum in gorillas

(2010) Weimin Liu et al.   NATURE

African great apes are natural hosts of multiple related malaria species, including Plasmodium falciparum

(2010) F. Prugnolle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sialic acids as regulators of molecular and cellular interactions

(2009) Roland Schauer   CURRENT OPINION IN STRUCTURAL BIOLOGY

Pseudomonas aeruginosa-Mediated Damage Requires Distinct Receptors at the Apical and Basolateral Surfaces of the Polarized Epithelium

(2009) I. Bucior et al.   INFECTION AND IMMUNITY

Members of a Novel Protein Family Containing Microneme Adhesive Repeat Domains Act as Sialic Acid-binding Lectins during Host Cell Invasion by Apicomplexan Parasites

(2009) Nikolas Friedrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis of binding of the Plasmodium falciparum receptor BAEBL to erythrocyte receptor glycophorin C

(2009) Lubin Jiang et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Human-specific evolution of sialic acid targets: Explaining the malignant malaria mystery?

(2009) A. Varki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery of a Salmonella Typhi Exotoxin from a Host Intracellular Compartment

(2008) Stefania Spanò et al.   Cell Host & Microbe

Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin

(2008) Emma Byres et al.   NATURE

Structural basis of GM1 ganglioside recognition by simian virus 40

(2008) Ursula Neu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sialic acids in human health and disease

(2008) Ajit Varki   TRENDS IN MOLECULAR MEDICINE