Nontypeable Haemophilus influenzae Has Evolved Preferential Use of N-Acetylneuraminic Acid as a Host Adaptation

The HMW2 adhesin of non-typeable Haemophilus influenzae is a human-adapted lectin that mediates high-affinity binding to 2–6 linked N -acetylneuraminic acid glycans

(2018) John M. Atack et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clinical and Bacteriologic Analysis of Nontypeable Haemophilus influenzae Strains Isolated from Children with Invasive Diseases in Japan from 2008 to 2015

(2018) Sachiko Naito et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR

(2016) Karina Hentrich et al.   Cell Host & Microbe

Clinical and Molecular Epidemiology of Childhood Invasive Nontypeable Haemophilus influenzae Disease in England and Wales

(2016) Sarah Collins et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Host Adaptation of a Bacterial Toxin from the Human Pathogen Salmonella Typhi

(2014) Lingquan Deng et al.   CELL

Antibodies to the HMW1/HMW2 and Hia Adhesins of Nontypeable Haemophilus influenzae Mediate Broad-Based Opsonophagocytic Killing of Homologous and Heterologous Strains

(2014) Linda E. Winter et al.   Clinical and Vaccine Immunology

A red meat-derived glycan promotes inflammation and cancer progression

(2014) Annie N. Samraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The burden of nonencapsulated Haemophilus influenzae in children and potential for prevention

(2012) Despoina Gkentzi et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Metabolism of Vertebrate Amino Sugars withN-Glycolyl Groups

(2012) Anne K. Bergfeld et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pasteurella multocida CMP-sialic acid synthetase and mutants of Neisseria meningitidis CMP-sialic acid synthetase with improved substrate promiscuity

(2011) Yanhong Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The high-resolution crystal structure of periplasmicHaemophilus influenzaeNAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism

(2011) Silvia Garavaglia et al.   BIOCHEMICAL JOURNAL

Human Xeno-Autoantibodies against a Non-Human Sialic Acid Serve as Novel Serum Biomarkers and Immunotherapeutics in Cancer

(2011) V. Padler-Karavani et al.   CANCER RESEARCH

Haemophilus influenzae Infections in the H. influenzae Type b Conjugate Vaccine Era

(2011) Aarti Agrawal et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acidN-glycolylneuraminic acid

(2010) Rachel E. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium

(2009) T. Pham et al.   BLOOD

Low incidence of N-glycolylneuraminic acid in birds and reptiles and its absence in the platypus

(2009) Roland Schauer et al.   CARBOHYDRATE RESEARCH

Sensitive and Specific Detection of the Non-Human Sialic Acid N-Glycolylneuraminic Acid In Human Tissues and Biotherapeutic Products

(2009) Sandra L. Diaz et al.   PLoS One

Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease

(2008) V. Padler-Karavani et al.   GLYCOBIOLOGY

Nontypeable Haemophilus influenzae as a Pathogen in Children

(2008) Timothy F. Murphy et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression

(2008) M. Hedlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA