Mammalian sialidases: Physiological and pathological roles in cellular functions

Effects of a human plasma membrane-associated sialidase siRNA on prostate cancer invasion

(2011) Xiaojie Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Substrate Recognition of the Membrane-Associated Sialidase NEU3 Requires a Hydrophobic Aglycone

(2011) Mahendra S. Sandbhor et al.   BIOCHEMISTRY

Plasma membrane-associated sialidase (NEU3) regulates progression of prostate cancer to androgen-independent growth through modulation of androgen receptor signaling

(2011) S Kawamura et al.   CELL DEATH AND DIFFERENTIATION

Where catabolism meets signalling: neuraminidase 1 as a modulator of cell receptors

(2011) Alexey V. Pshezhetsky et al.   GLYCOCONJUGATE JOURNAL

Neu1 Sialidase and Matrix Metalloproteinase-9 Cross-talk Is Essential for Toll-like Receptor Activation and Cellular Signaling

(2011) Samar Abdulkhalek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Sialyl Lewis Antigen Expression in Colon Cancer Cells by Sialidase NEU4

(2011) Kazuhiro Shiozaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1

(2011) Chiguang Feng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cell surface sphingolipid glycohydrolases in neuronal differentiation and aging in culture

(2011) Massimo Aureli et al.   JOURNAL OF NEUROCHEMISTRY

Imaging of sialidase activity in rat brain sections by a highly sensitive fluorescent histochemical method

(2011) Akira Minami et al.   NEUROIMAGE

Regulation of plasma-membrane-associated sialidaseNEU3gene by Sp1/Sp3 transcription factors

(2010) Kazunori Yamaguchi et al.   BIOCHEMICAL JOURNAL

Molecular mechanisms of pathogenesis in a glycosphingolipid and a glycoprotein storage disease

(2010) Alessandra d'Azzo et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid

(2010) Yao Zou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for neurotrophin activation of Trk receptors and cellular signaling

(2010) Preethi Jayanth et al.   CELLULAR SIGNALLING

Insight into substrate recognition and catalysis by the human neuraminidase 3 (NEU3) through molecular modeling and site-directed mutagenesis

(2010) Amgad Albohy et al.   GLYCOBIOLOGY

Desialylation of insulin receptors and IGF-1 receptors by neuraminidase-1 controls the net proliferative response of L6 myoblasts to insulin

(2010) M. Arabkhari et al.   GLYCOBIOLOGY

Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo

(2010) Trisha M. Finlay et al.   GLYCOCONJUGATE JOURNAL

LPS-induced cytokine production in human dendritic cells is regulated by sialidase activity

(2010) Nicholas M. Stamatos et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Complexity in Influenza Virus Targeted Drug Design: Interaction with Human Sialidases

(2010) Leonard M. G. Chavas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibody-mediated sialidase activity in blood serum of patients with multiple myeloma

(2010) Rostyslav Bilyy et al.   JOURNAL OF MOLECULAR RECOGNITION

Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility

(2010) Tura C. Camilli et al.   Pigment Cell & Melanoma Research

Sialidase enhances recovery from spinal cord contusion injury

(2010) A. Mountney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-125b promotes growth of prostate cancer xenograft tumor through targeting pro-apoptotic genes

(2010) Xu-Bao Shi et al.   PROSTATE

Mice Doubly-Deficient in Lysosomal Hexosaminidase A and Neuraminidase 4 Show Epileptic Crises and Rapid Neuronal Loss

(2010) Volkan Seyrantepe et al.   PLoS Genetics

Protective protein/cathepsin A rescues N-glycosylation defects in neuraminidase-1

(2009) Dongning Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Klotho and aging

(2009) Makoto Kuro-o   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Plasma membrane-associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice

(2009) Kazuhiro Shiozaki et al.   CANCER SCIENCE

Defective myogenic differentiation of human rhabdomyosarcoma cells is characterized by sialidase Neu2 loss of expression

(2009) Elena Stoppani et al.   CELL BIOLOGY INTERNATIONAL

Neu1 desialylation of sialyl α-2,3-linked β-galactosyl residues of TOLL-like receptor 4 is essential for receptor activation and cellular signaling

(2009) Schammim Ray Amith et al.   CELLULAR SIGNALLING

Raft component GD3 associates with tubulin following CD95/Fas ligation

(2009) Maurizio Sorice et al.   FASEB JOURNAL

Human sialidase NEU4 long and short are extrinsic proteins bound to outer mitochondrial membrane and the endoplasmic reticulum, respectively

(2009) Alessandra Bigi et al.   GLYCOBIOLOGY

Down regulation of membrane-bound Neu3 constitutes a new potential marker for childhood acute lymphoblastic leukemia and induces apoptosis suppression of neoplastic cells

(2009) Chandan Mandal et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of Phagocytosis in Macrophages by Neuraminidase 1

(2009) Volkan Seyrantepe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developmental Change of Sialidase Neu4 Expression in Murine Brain and Its Involvement in the Regulation of Neuronal Cell Differentiation

(2009) Kazuhiro Shiozaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterodimerization of the Sialidase NEU1 with the Chaperone Protective Protein/Cathepsin A Prevents Its Premature Oligomerization

(2009) Erik J. Bonten et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a

(2009) Jianfeng Wang et al.   JOURNAL OF NEUROCHEMISTRY

GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

(2009) Renata Sano et al.   MOLECULAR CELL

Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin β4

(2009) T Uemura et al.   ONCOGENE

Neuraminidase-1, a Subunit of the Cell Surface Elastin Receptor, Desialylates and Functionally Inactivates Adjacent Receptors Interacting with the Mitogenic Growth Factors PDGF-BB and IGF-2

(2008) Aleksander Hinek et al.   AMERICAN JOURNAL OF PATHOLOGY

Limited Inhibitory Effects of Oseltamivir and Zanamivir on Human Sialidases

(2008) K. Hata et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sp1: Emerging roles—Beyond constitutive activation of TATA-less housekeeping genes

(2008) Inken Wierstra   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Accumulation of free complex-type N-glycans in MKN7 and MKN45 stomach cancer cells

(2008) Aya Ishizuka et al.   BIOCHEMICAL JOURNAL

Glycobiology in the cytosol: The bitter side of a sweet world

(2008) Yoko Funakoshi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Enzymatic Activity of Lysosomal Carboxypeptidase (Cathepsin) A Is Required for Proper Elastic Fiber Formation and Inactivation of Endothelin-1

(2008) Volkan Seyrantepe et al.   CIRCULATION

Neuraminidase 1 Is a Negative Regulator of Lysosomal Exocytosis

(2008) Gouri Yogalingam et al.   DEVELOPMENTAL CELL

Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage

(2008) Volkan Seyrantepe et al.   HUMAN MOLECULAR GENETICS

Plasma Membrane-associated Sialidase as a Crucial Regulator of Transmembrane Signalling

(2008) T. Miyagi et al.   JOURNAL OF BIOCHEMISTRY

NEU3 Sialidase Strictly Modulates GM3 Levels in Skeletal Myoblasts C2C12 Thus Favoring Their Differentiation and Protecting Them from Apoptosis

(2008) Luigi Anastasia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1

(2008) Laurence Veracini et al.   JOURNAL OF CELL BIOLOGY

Aberrant expression of sialidase and cancer progression

(2008) Taeko MIYAGI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

(2008) S.-K. Cha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: Selective inhibitors of lysosomal sialidase (NEU1)

(2007) Sadagopan Magesh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS