Alzheimer’s-Like Pathology at the Crossroads of HIV-Associated Neurological Disorders
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Alzheimer’s-Like Pathology at the Crossroads of HIV-Associated Neurological Disorders
Authors
Keywords
-
Journal
Vaccines
Volume 9, Issue 8, Pages 930
Publisher
MDPI AG
Online
2021-08-23
DOI
10.3390/vaccines9080930
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism
- (2021) Lisa K. Smith et al. PLoS One
- HIV-1 Latency and Viral Reservoirs: Existing Reversal Approaches and Potential Technologies, Targets, and Pathways Involved in HIV Latency Studies
- (2021) Sushant Khanal et al. Cells
- Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier
- (2021) Mariana Castro Dias et al. JOURNAL OF CELL SCIENCE
- Investigating the role of pericytes in cerebral autoregulation: a modelling study
- (2021) Selena Milanovic et al. PHYSIOLOGICAL MEASUREMENT
- Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease
- (2021) Jong-Sung Park et al. Acta Neuropathologica Communications
- Beta amyloid levels in CSF of HIV-infected people vary by exposure to antiretroviral therapy
- (2020) Jerel Adam Fields et al. AIDS
- HIV-1 Tat-mediated astrocytic amyloidosis involves the HIF-1α/lncRNA BACE1-AS axis
- (2020) Susmita Sil et al. PLOS BIOLOGY
- Modification of lipid rafts by extracellular vesicles carrying HIV-1 protein Nef induces redistribution of APP and Tau causing neuronal dysfunction
- (2020) Michael Ditiatkovski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamic Blood Concentrations of Aβ1–40 and Aβ1–42 in Alzheimer’s Disease
- (2020) Yuan-Han Yang et al. Frontiers in Cell and Developmental Biology
- Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis
- (2020) A Borrajo et al. ANNALS OF MEDICINE
- Global prevalence and burden of HIV-associated neurocognitive disorder: a meta-analysis
- (2020) Yunhe Wang et al. NEUROLOGY
- Chronic morphine administration differentially modulates viral reservoirs in SIVmac251 infected rhesus macaque model
- (2020) Arpan Acharya et al. JOURNAL OF VIROLOGY
- Plasma neuronal exosomes serve as biomarkers of cognitive impairment in HIV infection and Alzheimer’s disease
- (2019) Lynn Pulliam et al. JOURNAL OF NEUROVIROLOGY
- Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice
- (2019) Saumi Mathews et al. Molecular Neurodegeneration
- Does HIV infection contribute to increased beta-amyloid synthesis and plaque formation leading to neurodegeneration and Alzheimer’s disease?
- (2019) Tamas Fulop et al. JOURNAL OF NEUROVIROLOGY
- CRISPR/Cas9 Editing of Glia Maturation Factor Regulates Mitochondrial Dynamics by Attenuation of the NRF2/HO-1 Dependent Ferritin Activation in Glial Cells
- (2019) Govindhasamy Pushpavathi Selvakumar et al. Journal of Neuroimmune Pharmacology
- Role of the inflammasomes in HIV-associated neuroinflammation and neurocognitive disorders
- (2019) Akhil Katuri et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- HIV-1 Tat-mediated microglial inflammation involves a novel miRNA-34a-NLRC5-NFκB signaling axis
- (2019) Palsamy Periyasamy et al. BRAIN BEHAVIOR AND IMMUNITY
- The impact of HIV CNS persistence on pathogenesis
- (2019) Bruce J. Brew et al. AIDS
- Imaging correlates of the Blood Brain Barrier disruption in HIV associated neurocognitive disorder and therapeutic implications
- (2019) Joga Chaganti et al. AIDS
- HIV Infection Induces Extracellular Cathepsin B Uptake and Damage to Neurons
- (2019) Yisel M. Cantres-Rosario et al. Scientific Reports
- Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia
- (2019) Daniel T. Claiborne et al. JOURNAL OF VIROLOGY
- A Broad Application of CRISPR Cas9 in Infectious, Inflammatory and Neurodegenerative Diseases
- (2019) Kalipada Pahan Journal of Neuroimmune Pharmacology
- Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood–brain-barrier permeability
- (2019) Jocelyn Rivera et al. PLoS One
- Nef-induced CCL2 Expression Contributes to HIV/SIV Brain Invasion and Neuronal Dysfunction
- (2019) Michael H. Lehmann et al. Frontiers in Immunology
- Getting the “Kill” into “Shock and Kill”: Strategies to Eliminate Latent HIV
- (2018) Youry Kim et al. Cell Host & Microbe
- Markers for human brain pericytes and smooth muscle cells
- (2018) Leon C.D. Smyth et al. JOURNAL OF CHEMICAL NEUROANATOMY
- BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism
- (2018) Anna L. Stern et al. JOURNAL OF NEUROSCIENCE
- HIV Associated Neurocognitive Impairment in Diverse Resource Limited Settings
- (2018) Kevin R Robertson et al. CLINICAL INFECTIOUS DISEASES
- Deletion of the Cathepsin B Gene Improves Memory Deficits in a Transgenic Alzheimer's Disease Mouse Model Expressing AβPP Containing the Wild-Type β-Secretase Site Sequence
- (2018) Mark S. Kindy et al. JOURNAL OF ALZHEIMERS DISEASE
- Morphine Potentiates Dysbiotic Microbial and Metabolic Shifts in Acute SIV Infection
- (2018) Gregory M. Sindberg et al. Journal of Neuroimmune Pharmacology
- Alzheimer’s disease neuropathology may not predict functional impairment in HIV: a report of two individuals
- (2018) Susan Morgello et al. JOURNAL OF NEUROVIROLOGY
- HIV Neuroinfection and Alzheimer’s Disease: Similarities and Potential Links?
- (2018) Geoffrey Canet et al. Frontiers in Cellular Neuroscience
- Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer’s Disease?
- (2018) Tamas Fulop et al. Frontiers in Aging Neuroscience
- Blood–brain barrier pericytes as a target for HIV-1 infection
- (2018) Luc Bertrand et al. BRAIN
- Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing
- (2018) Taha Mohseni Ahooyi et al. Scientific Reports
- PET brain imaging in HIV-associated neurocognitive disorders (HAND) in the era of combination antiretroviral therapy
- (2017) Jaime H. Vera et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- In vitro modeling of HIV proviral activity in microglia
- (2017) Lee A. Campbell et al. FEBS Journal
- Protective and Pathological Immunity during Central Nervous System Infections
- (2017) Robyn S. Klein et al. IMMUNITY
- HIV-1 Tat Primes and Activates Microglial NLRP3 Inflammasome-Mediated Neuroinflammation
- (2017) Ernest T. Chivero et al. JOURNAL OF NEUROSCIENCE
- T Cell-Macrophage Fusion Triggers Multinucleated Giant Cell Formation for HIV-1 Spreading
- (2017) Lucie Bracq et al. JOURNAL OF VIROLOGY
- Extracellular vesicles of the blood-brain barrier: Role in the HIV-1 associated amyloid beta pathology
- (2017) Ibolya E. András et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity
- (2017) Alina Hategan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain
- (2017) Ira Espuny-Camacho et al. NEURON
- HIV Latency: Should We Shock or Lock?
- (2017) Gilles Darcis et al. TRENDS IN IMMUNOLOGY
- HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration
- (2017) Qingqing Chai et al. Nature Communications
- HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity
- (2017) Alina Hategan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Differentiating HIV-Associated Neurocognitive Disorders From Alzheimer’s Disease: an Emerging Issue in Geriatric NeuroHIV
- (2017) Benedetta Milanini et al. Current HIV/AIDS Reports
- Higher Cathepsin B Levels in Plasma in Alzheimer's Disease Compared to Healthy Controls
- (2017) Johan Sundelöf et al. JOURNAL OF ALZHEIMERS DISEASE
- HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim
- (2017) Paul Castellano et al. Scientific Reports
- Plasma microRNA profiling predicts HIV-associated neurocognitive disorder
- (2016) Eugene L. Asahchop et al. AIDS
- Update of Survival for Persons With HIV Infection in Denmark
- (2016) Nicolai Lohse et al. ANNALS OF INTERNAL MEDICINE
- Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer’s disease
- (2016) Edward J. Goetzl et al. FASEB JOURNAL
- HIV and aging
- (2016) Edward J. Wing INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Inflammasomes link vascular disease with neuroinflammation and brain disorders
- (2016) Nikolett Lénárt et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Effects of Morphine on Behavioral Task Performance in SIV-Infected Rhesus Macaques
- (2016) Joanne K. Marcario et al. Journal of Neuroimmune Pharmacology
- HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads
- (2016) Susanna L. Lamers et al. JOURNAL OF VIROLOGY
- HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment
- (2016) Deanna Saylor et al. Nature Reviews Neurology
- The neurotrophin receptor p75 mediates gp120-induced loss of synaptic spines in aging mice
- (2016) Alessia Bachis et al. NEUROBIOLOGY OF AGING
- Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study
- (2016) Magnus Gisslén et al. EBioMedicine
- Interacting partners of macrophage-secreted cathepsin B contribute to HIV-induced neuronal apoptosis
- (2015) Yisel M. Cantres-Rosario et al. AIDS
- Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study
- (2015) Massimo S. Fiandaca et al. Alzheimers & Dementia
- APOE ε4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals – a cross-sectional observational study
- (2015) Lucette A Cysique et al. BMC Neurology
- Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications
- (2015) Suzi Hong et al. BRAIN BEHAVIOR AND IMMUNITY
- Continued Slow Decay of the Residual Plasma Viremia Level in HIV-1–Infected Adults Receiving Long-term Antiretroviral Therapy
- (2015) Sharon A. Riddler et al. JOURNAL OF INFECTIOUS DISEASES
- Central and peripheral markers of neurodegeneration and monocyte activation in HIV-associated neurocognitive disorders
- (2015) Jennifer L McGuire et al. JOURNAL OF NEUROVIROLOGY
- Blood brain barrier impairment is associated with cerebrospinal fluid markers of neuronal damage in HIV-positive patients
- (2015) A. Calcagno et al. JOURNAL OF NEUROVIROLOGY
- Microglia-derived HIV Nef+ exosome impairment of the blood–brain barrier is treatable by nanomedicine-based delivery of Nef peptides
- (2015) A. D. Raymond et al. JOURNAL OF NEUROVIROLOGY
- Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study
- (2015) Ned Sacktor et al. NEUROLOGY
- Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease
- (2015) Edward J. Goetzl et al. NEUROLOGY
- Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection
- (2015) NEW ENGLAND JOURNAL OF MEDICINE
- Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice
- (2015) Michael D Boska et al. Molecular Neurodegeneration
- Low levels of HIV-1 RNA detected in the cerebrospinal fluid after up to 10 years of suppressive therapy are associated with local immune activation
- (2014) Viktor Dahl et al. AIDS
- The impact of HIV-1 on neurogenesis: implications for HAND
- (2014) Darren Ferrell et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Role of HIV in Amyloid Metabolism
- (2014) Mario Ortega et al. Journal of Neuroimmune Pharmacology
- Astrocytic expression of HIV-1 viral protein R in the hippocampus causes chromatolysis, synaptic loss and memory impairment
- (2014) Lilith Torres et al. Journal of Neuroinflammation
- Exosomes as mediators of neuroinflammation
- (2014) Archana Gupta et al. Journal of Neuroinflammation
- Tat 101-Mediated Enhancement of Brain Pericyte Migration Involves Platelet-Derived Growth Factor Subunit B Homodimer: Implications for Human Immunodeficiency Virus-Associated Neurocognitive Disorders
- (2014) F. Niu et al. JOURNAL OF NEUROSCIENCE
- Circulating Biomarkers of Immune Activation Distinguish Viral Suppression from Nonsuppression in HAART-Treated Patients with Advanced HIV-1 Subtype C Infection
- (2014) Glen Malherbe et al. MEDIATORS OF INFLAMMATION
- Single App knock-in mouse models of Alzheimer's disease
- (2014) Takashi Saito et al. NATURE NEUROSCIENCE
- HIV-1 Nef Impairs Key Functional Activities in Human Macrophages through CD36 Downregulation
- (2014) Eleonora Olivetta et al. PLoS One
- Prepulse inhibition in HIV-1 gp120 transgenic mice after withdrawal from chronic methamphetamine
- (2013) Brook L. Henry et al. BEHAVIOURAL PHARMACOLOGY
- Cerebrospinal Fluid and Neuroimaging Biomarker Abnormalities Suggest Early Neurological Injury in a Subset of Individuals During Primary HIV Infection
- (2013) M. J. Peluso et al. JOURNAL OF INFECTIOUS DISEASES
- Endolysosome involvement in HIV-1 transactivator protein-induced neuronal amyloid beta production
- (2013) Xuesong Chen et al. NEUROBIOLOGY OF AGING
- HIV-1 Tat Interacts with and Regulates the Localization and Processing of Amyloid Precursor Protein
- (2013) Jiyoung Kim et al. PLoS One
- Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein
- (2013) T. P. Johnson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Positron Emission Tomography Applications in Clinical Neurology
- (2013) Tarun Singhal SEMINARS IN NEUROLOGY
- Pericyte loss influences Alzheimer-like neurodegeneration in mice
- (2013) Abhay P. Sagare et al. Nature Communications
- HIV-1-Related Central Nervous System Disease: Current Issues in Pathogenesis, Diagnosis, and Treatment
- (2013) S. Spudich et al. Cold Spring Harbor Perspectives in Medicine
- HIV: Cell Binding and Entry
- (2013) C. B. Wilen et al. Cold Spring Harbor Perspectives in Medicine
- Amyloid PET in clinical practice: Its place in the multidimensional space of Alzheimer's disease
- (2013) Rik Vandenberghe et al. NeuroImage-Clinical
- Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells
- (2012) Ibolya E. András et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Assessment, Diagnosis, and Treatment of HIV-Associated Neurocognitive Disorder: A Consensus Report of the Mind Exchange Program
- (2012) et al. CLINICAL INFECTIOUS DISEASES
- Amyloid beta accumulation in HIV-1-infected brain: The role of the blood brain barrier
- (2012) Ibolya E. András et al. IUBMB LIFE
- Higher CNS Penetration-Effectiveness of Long-term Combination Antiretroviral Therapy Is Associated With Better HIV-1 Viral Suppression in Cerebrospinal Fluid
- (2012) Alexia Cusini et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Infection of human pericytes by HIV-1 disrupts the integrity of the blood-brain barrier
- (2012) Shinsuke Nakagawa et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Cerebrospinal fluid miRNA profile in HIV-encephalitis
- (2012) Marco Pacifici et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection
- (2012) Victor Valcour et al. JOURNAL OF INFECTIOUS DISEASES
- Identification and proteomic profiling of exosomes in human cerebrospinal fluid
- (2012) Jonathan M Street et al. Journal of Translational Medicine
- Astrocytic expression of HIV-1 Nef impairs spatial and recognition memory
- (2012) Gladys Chompre et al. NEUROBIOLOGY OF DISEASE
- Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients
- (2012) Kenneth W Witwer et al. Retrovirology
- Recently Infiltrating MAC387+ Monocytes/Macrophages
- (2011) Caroline Soulas et al. AMERICAN JOURNAL OF PATHOLOGY
- Breaking down the barrier: The effects of HIV-1 on the blood–brain barrier
- (2011) Marianne Strazza et al. BRAIN RESEARCH
- Premature Age-Related Comorbidities Among HIV-Infected Persons Compared With the General Population
- (2011) G. Guaraldi et al. CLINICAL INFECTIOUS DISEASES
- HIV-1 gp120-Induced Axonal Injury Detected by Accumulation of β-Amyloid Precursor Protein in Adult Rat Corpus Callosum
- (2011) Jingdong Zhang et al. Journal of Neuroimmune Pharmacology
- Delineating HIV-Associated Neurocognitive Disorders Using Transgenic Models: The Neuropathogenic Actions of Vpr
- (2011) Christopher Power et al. Journal of Neuroimmune Pharmacology
- Loss of Neuronal Integrity during Progressive HIV-1 Infection of Humanized Mice
- (2011) P. K. Dash et al. JOURNAL OF NEUROSCIENCE
- Pericyte-derived Glial Cell Line-derived Neurotrophic Factor Increase the Expression of Claudin-5 in the Blood–brain Barrier and the Blood-nerve Barrier
- (2011) Fumitaka Shimizu et al. NEUROCHEMICAL RESEARCH
- Humanized Rag1−/−γc−/− Mice Support Multilineage Hematopoiesis and Are Susceptible to HIV-1 Infection via Systemic and Vaginal Routes
- (2011) Ramesh Akkina et al. PLoS One
- Blood–Brain Barrier Permeability Abnormalities in Vascular Cognitive Impairment
- (2011) Saeid Taheri et al. STROKE
- Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: Implications for HIV-associated neurocognitive disorders
- (2011) Brian Giunta et al. Molecular Brain
- Links between Progressive HIV-1 Infection of Humanized Mice and Viral Neuropathogenesis
- (2010) Santhi Gorantla et al. AMERICAN JOURNAL OF PATHOLOGY
- Discordance Between Cerebral Spinal Fluid and Plasma HIV Replication in Patients with Neurological Symptoms Who Are Receiving Suppressive Antiretroviral Therapy
- (2010) Ana Canestri et al. CLINICAL INFECTIOUS DISEASES
- MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase-6 regulates astrocyte survival
- (2010) Farshid Noorbakhsh et al. FASEB JOURNAL
- HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors
- (2010) Robert K. Heaton et al. JOURNAL OF NEUROVIROLOGY
- Use of dynamic contrast-enhanced MRI to measure subtle blood–brain barrier abnormalities
- (2010) Paul A. Armitage et al. MAGNETIC RESONANCE IMAGING
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease
- (2010) Myoung-Hwa Lee et al. NEUROBIOLOGY OF DISEASE
- HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study
- (2010) R. K. Heaton et al. NEUROLOGY
- HIV-1 protein-mediated amyloidogenesis in rat hippocampal cell cultures
- (2010) M.Y. Aksenov et al. NEUROSCIENCE LETTERS
- Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia
- (2009) Melissa J. Churchill et al. ANNALS OF NEUROLOGY
- Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
- (2009) Leslie M. Shaw et al. ANNALS OF NEUROLOGY
- Amyloid and tau cerebrospinal fluid biomarkers in HIV infection
- (2009) Magnus Gisslén et al. BMC Neurology
- Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
- (2009) Jesus F. Salazar-Gonzalez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Amyloid Interaction with Receptor for Advanced Glycation End Products Up-Regulates Brain Endothelial CCR5 Expression and Promotes T Cells Crossing the Blood-Brain Barrier
- (2009) M. Li et al. JOURNAL OF IMMUNOLOGY
- Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients
- (2009) Cristian L. Achim et al. Journal of Neuroimmune Pharmacology
- Acquired immunodeficiency syndrome and the blood-brain barrier
- (2009) Nathan S Ivey et al. JOURNAL OF NEUROVIROLOGY
- HIV-1-induced amyloid beta accumulation in brain endothelial cells is attenuated by simvastatin
- (2009) Ibolya E. András et al. MOLECULAR AND CELLULAR NEUROSCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started