HIV-1 Tat-mediated astrocytic amyloidosis involves the HIF-1α/lncRNA BACE1-AS axis

BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism

(2018) Anna L. Stern et al.   JOURNAL OF NEUROSCIENCE

Epigenetic promoter DNA methylation of miR-124 promotes HIV-1 Tat-mediated microglial activation via MECP2-STAT3 axis

(2018) Palsamy Periyasamy et al.   JOURNAL OF NEUROSCIENCE

Morphine-Mediated Brain Region-Specific Astrocytosis Involves the ER Stress-Autophagy Axis

(2018) Susmita Sil et al.   MOLECULAR NEUROBIOLOGY

Author Correction: HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration

(2018) Qingqing Chai et al.   Nature Communications

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production

(2018) Rawan El-Amine et al.   Redox Biology

Antiretroviral exposure and comorbidities in an aging HIV-infected population: The challenge of geriatric patients

(2018) Clotilde Allavena et al.   PLoS One

Induction of HIF-1α by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation

(2018) Gabriel Duette et al.   mBio

HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity

(2017) Alina Hategan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity

(2017) Alina Hategan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer

(2017) Luisa Iommarini et al.   Frontiers in Oncology

Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

(2016) Elizabeth E. Spangenberg et al.   BRAIN

B Cell-Directed Therapeutics in Multiple Sclerosis: Rationale and Clinical Evidence

(2016) Silke Kinzel et al.   CNS DRUGS

HIV-1 Tat Regulates Occludin and AβTransfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway

(2016) Yanlan Chen et al.   Oxidative Medicine and Cellular Longevity

Dysregulation of autophagy by HIV-1 Nef in human astrocytes

(2015) A Sami Saribas et al.   CELL CYCLE

Role of the macrophage in HIV-associated neurocognitive disorders and other comorbidities in patients on effective antiretroviral treatment

(2015) Jay Rappaport et al.   JOURNAL OF NEUROVIROLOGY

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α

(2015) Yoko Goto et al.   Nature Communications

The role of microglia in human disease: therapeutic tool or target?

(2014) Nathalie Cartier et al.   ACTA NEUROPATHOLOGICA

Persistent immune activation in chronic HIV infection

(2013) Reena Rajasuriar et al.   AIDS

Fluid biomarkers in Alzheimer’s disease – current concepts

(2013) Christoffer Rosén et al.   Molecular Neurodegeneration

Endolysosome involvement in HIV-1 transactivator protein-induced neuronal amyloid beta production

(2013) Xuesong Chen et al.   NEUROBIOLOGY OF AGING

HIV-1 Tat Interacts with and Regulates the Localization and Processing of Amyloid Precursor Protein

(2013) Jiyoung Kim et al.   PLoS One

Release of Luminal Exosomes Contributes to TLR4-Mediated Epithelial Antimicrobial Defense

(2013) Guoku Hu et al.   PLoS Pathogens

Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers

(2012) Virawudh Soontornniyomkij et al.   AIDS

11C-PiB Imaging of Human Immunodeficiency Virus–Associated Neurocognitive Disorder

(2012) Beau M. Ances   ARCHIVES OF NEUROLOGY

Human Immunodeficiency Virus Type 1 Alters Brain-Derived Neurotrophic Factor Processing in Neurons

(2012) A. Bachis et al.   JOURNAL OF NEUROSCIENCE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Morphine Potentiates Neuropathogenesis of SIV Infection in Rhesus Macaques

(2011) Sirosh M. Bokhari et al.   Journal of Neuroimmune Pharmacology

A Growth Factor Attenuates HIV-1 Tat and Morphine Induced Damage to Human Neurons: Implication in HIV/AIDS-Drug Abuse Cases

(2011) Shaily Malik et al.   PLoS One

Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: Implications for HIV-associated neurocognitive disorders

(2011) Brian Giunta et al.   Molecular Brain

Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease

(2010) Dimitrios Kapogiannis et al.   LANCET NEUROLOGY

Cognitively unimpaired HIV-positive subjects do not have increased 11C-PiB: A case-control study

(2010) B. M. Ances et al.   NEUROLOGY

Amyloid and tau cerebrospinal fluid biomarkers in HIV infection

(2009) Magnus Gisslén et al.   BMC Neurology

Contribution of hypoxia to Alzheimer’s disease: is HIF-1α a mediator of neurodegeneration?

(2009) O. O. Ogunshola et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Activation of the Oxidative Stress Pathway by HIV-1 Vpr Leads to Induction of Hypoxia-inducible Factor 1α Expression

(2009) Satish L. Deshmane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV Regulation of Amyloid Beta Production

(2009) Lynn Pulliam   Journal of Neuroimmune Pharmacology

Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients

(2009) Cristian L. Achim et al.   Journal of Neuroimmune Pharmacology

HIV-1-induced amyloid beta accumulation in brain endothelial cells is attenuated by simvastatin

(2009) Ibolya E. András et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease

(2009) D. B. Clifford et al.   NEUROLOGY

The Comorbidity of HIV-Associated Neurocognitive Disorders and Alzheimer’s Disease: A Foreseeable Medical Challenge in Post-HAART Era

(2008) Jiqing Xu et al.   Journal of Neuroimmune Pharmacology

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Simvastatin Protects against Amyloid   and HIV-1 Tat-Induced Promoter Activities of Inflammatory Genes in Brain Endothelial Cells

(2008) I. E. Andras et al.   MOLECULAR PHARMACOLOGY

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE