Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood–brain-barrier permeability

Astrocytes sustain long-term productive HIV-1 infection without establishment of reactivable viral latency

(2018) Corinne Barat et al.   GLIA

Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA

(2018) Jana Ferdin et al.   PLoS One

Letter to Editor

(2018) Lena Al-Harthi et al.   Journal of Neuroimmune Pharmacology

HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis

(2017) Jadwiga Nitkiewicz et al.   Journal of Neuroinflammation

Brain-specific HIV Nef identified in multiple patients with neurological disease

(2017) Susanna L. Lamers et al.   JOURNAL OF NEUROVIROLOGY

Nef is secreted in exosomes from Nef.GFP-expressing and HIV-1-infected human astrocytes

(2017) Pia Pužar Dominkuš et al.   JOURNAL OF NEUROVIROLOGY

Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain

(2017) Eugene L. Asahchop et al.   Retrovirology

HIV-1 Nef is released in extracellular vesicles derived from astrocytes: evidence for Nef-mediated neurotoxicity

(2017) A Sami Saribas et al.   Cell Death & Disease

A CRISPR/Cas9 guidance RNA screen platform for HIV provirus disruption and HIV/AIDS gene therapy in astrocytes

(2017) Zaohua Huang et al.   Scientific Reports

Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material

(2017) Rebecca A. Russell et al.   Cell Reports

Astrocytes as an HIV Reservoir: Mechanism of HIV Infection

(2016) Guan-Han Li et al.   CURRENT HIV RESEARCH

Cell-to-cell contact facilitates HIV transmission from lymphocytes to astrocytes via CXCR4

(2015) Guan-Han Li et al.   AIDS

Double immunofluorescent staining of rat macrophages in formalin-fixed paraffin-embedded tissue using two monoclonal mouse antibodies

(2015) Raymond A. Isidro et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Nef exosomes isolated from the plasma of individuals with HIV-associated dementia (HAD) can induce Aβ1–42 secretion in SH-SY5Y neural cells

(2015) Mahfuz B. Khan et al.   JOURNAL OF NEUROVIROLOGY

Microglia-derived HIV Nef+ exosome impairment of the blood–brain barrier is treatable by nanomedicine-based delivery of Nef peptides

(2015) A. D. Raymond et al.   JOURNAL OF NEUROVIROLOGY

Differential signaling mechanism for HIV-1 Nef-mediated production of IL-6 and IL-8 in human astrocytes

(2015) Xun Liu et al.   Scientific Reports

The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders

(2015) Sonia Mediouni et al.   Frontiers in Microbiology

HIV-1 reprograms the migration of macrophages

(2014) C. Verollet et al.   BLOOD

HIV-1 Nef expression in microglia disrupts dopaminergic and immune functions with associated mania-like behaviors

(2014) Shaona Acharjee et al.   BRAIN BEHAVIOR AND IMMUNITY

Cell–cell contact viral transfer contributes to HIV infection and persistence in astrocytes

(2014) Xiaoyu Luo et al.   JOURNAL OF NEUROVIROLOGY

Transfer of Intracellular HIV Nef to Endothelium Causes Endothelial Dysfunction

(2014) Ting Wang et al.   PLoS One

Is the central nervous system a reservoir of HIV-1?

(2014) Lachlan R. Gray et al.   Current Opinion in HIV and AIDS

HIV-1 Nef Induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors

(2014) Xun Liu et al.   Scientific Reports

Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells

(2013) Mirjam Schenk et al.   IMMUNOLOGY

Oral Antiretroviral Drugs as Public Health Tools for HIV Prevention: Global Implications for Adherence, Drug Resistance, and the Success of HIV Treatment Programs

(2013) Ravindra K. Gupta et al.   JOURNAL OF INFECTIOUS DISEASES

Epigenetic Regulation of HIV-1 Latency in Astrocytes

(2013) S. D. Narasipura et al.   JOURNAL OF VIROLOGY

Identification of Novel T Cell Factor 4 (TCF-4) Binding Sites on the HIV Long Terminal Repeat Which Associate with TCF-4,  -Catenin, and SMAR1 To Repress HIV Transcription

(2012) L. J. Henderson et al.   JOURNAL OF VIROLOGY

Astrocytic expression of HIV-1 Nef impairs spatial and recognition memory

(2012) Gladys Chompre et al.   NEUROBIOLOGY OF DISEASE

Peripheral inflammatory disease associated with centrally activated IL-1 system in humans and mice

(2012) J. Lampa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulmonary-intestinal cross-talk in mucosal inflammatory disease

(2011) S Keely et al.   Mucosal Immunology

HIV-1 Nef Protein Structures Associated with Brain Infection and Dementia Pathogenesis

(2011) Susanna L. Lamers et al.   PLoS One

Exogenous HIV-1 Nef Upsets the IFN-γ-Induced Impairment of Human Intestinal Epithelial Integrity

(2011) Maria Giovanna Quaranta et al.   PLoS One

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of cyclin B1–Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis

(2010) Olivier Gavet et al.   JOURNAL OF CELL BIOLOGY

Golgi dysfunction is a common feature in idiopathic human pulmonary hypertension and vascular lesions in SHIV-nef-infected macaques

(2009) Pravin B. Sehgal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

(2009) Melissa J. Churchill et al.   ANNALS OF NEUROLOGY

Systemic inflammatory response following acute traumatic brain injury

(2009) Jia Lu   Frontiers in Bioscience-Landmark

HIV-1 Nef-mediated inhibition of T cell migration and its molecular determinants

(2009) In-Woo Park et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Traumatic Brain Injury and Intestinal Dysfunction: Uncovering the Neuro-Enteric Axis

(2009) Vishal Bansal et al.   JOURNAL OF NEUROTRAUMA

HIV-1 Nef Inhibits Ruffles, Induces Filopodia, and Modulates Migration of Infected Lymphocytes

(2009) C. Nobile et al.   JOURNAL OF VIROLOGY

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

(2009) Weifeng Xu et al.   NATURE IMMUNOLOGY

Acute Lung Injury in Patients with Severe Brain Injury: A Double Hit Model

(2009) Luciana Mascia   Neurocritical Care