Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain
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Title
Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-08-13
DOI
10.3389/fimmu.2021.730088
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Note: Only part of the references are listed.- Guillain-Barré syndrome
- (2021) Nortina Shahrizaila et al. LANCET
- HIF-1, the Warburg Effect, and Macrophage/Microglia Polarization Potential Role in COVID-19 Pathogenesis
- (2021) Elisabetta Ferraro et al. Oxidative Medicine and Cellular Longevity
- SARS-CoV-2 targets MAVS for immune evasion
- (2021) Alessia Zotta et al. NATURE CELL BIOLOGY
- The RNA sensor MDA5 detects SARS-CoV-2 infection
- (2021) Natalia G. Sampaio et al. Scientific Reports
- Coronavirus infections and immune responses
- (2020) Geng Li et al. JOURNAL OF MEDICAL VIROLOGY
- Emerging coronaviruses: Genome structure, replication, and pathogenesis
- (2020) Yu Chen et al. JOURNAL OF MEDICAL VIROLOGY
- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- A novel coronavirus outbreak of global health concern
- (2020) Chen Wang et al. LANCET
- Another Decade, Another Coronavirus
- (2020) Stanley Perlman NEW ENGLAND JOURNAL OF MEDICINE
- Emerging novel coronavirus (2019-nCoV)—current scenario, evolutionary perspective based on genome analysis and recent developments
- (2020) Yashpal Singh Malik et al. VETERINARY QUARTERLY
- Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data
- (2020) Natalie M. Linton et al. Journal of Clinical Medicine
- SARS-CoV-2 Detected in Cerebrospinal Fluid by PCR in a Case of COVID-19 Encephalitis
- (2020) Y. Hanna Huang et al. BRAIN BEHAVIOR AND IMMUNITY
- Nervous system involvement after infection with COVID-19 and other coronaviruses
- (2020) Yeshun Wu et al. BRAIN BEHAVIOR AND IMMUNITY
- SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract
- (2020) Yixuan J. Hou et al. CELL
- Self-reported Olfactory and Taste Disorders in Patients With Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study
- (2020) Andrea Giacomelli et al. CLINICAL INFECTIOUS DISEASES
- Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment
- (2020) Mehmet Soy et al. CLINICAL RHEUMATOLOGY
- ACE2, COVID-19, and ACE Inhibitor and ARB Use during the Pandemic: The Pediatric Perspective
- (2020) Andrew M. South et al. HYPERTENSION
- Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals
- (2020) Ling Ni et al. IMMUNITY
- A first case of meningitis/encephalitis associated with SARS-Coronavirus-2
- (2020) Takeshi Moriguchi et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy
- (2020) Giacomo Grasselli et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The many faces of the anti-COVID immune response
- (2020) Santosha A. Vardhana et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Characteristics of ischaemic stroke associated with COVID-19
- (2020) Rahma Beyrouti et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Anosmia and Ageusia: Common Findings in COVID-19 Patients
- (2020) Luigi A. Vaira et al. LARYNGOSCOPE
- Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19
- (2020) Mingfeng Liao et al. NATURE MEDICINE
- Potential neurological impact of coronaviruses: implications for the novel SARS-CoV-2
- (2020) Joy D. Iroegbu et al. NEUROLOGICAL SCIENCES
- Involvement of the Nervous System in SARS-CoV-2 Infection
- (2020) Hao Li et al. NEUROTOXICITY RESEARCH
- Death from Covid-19 of 23 Health Care Workers in China
- (2020) Mingkun Zhan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Guillain–Barré Syndrome Associated with SARS-CoV-2
- (2020) Gianpaolo Toscano et al. NEW ENGLAND JOURNAL OF MEDICINE
- Neurologic Features in Severe SARS-CoV-2 Infection
- (2020) Julie Helms et al. NEW ENGLAND JOURNAL OF MEDICINE
- Multiorgan and Renal Tropism of SARS-CoV-2
- (2020) Victor G. Puelles et al. NEW ENGLAND JOURNAL OF MEDICINE
- COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features
- (2020) Neo Poyiadji et al. RADIOLOGY
- The Oral-Lung Axis: The Impact of Oral Health on Lung Health
- (2020) Nathaniel T Gaeckle et al. Respiratory Care
- Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China
- (2020) Ling Mao et al. JAMA Neurology
- COVID-19-driven endothelial damage: complement, HIF-1, and ABL2 are potential pathways of damage and targets for cure
- (2020) Monia Marchetti ANNALS OF HEMATOLOGY
- The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease
- (2020) Dennis McGonagle et al. AUTOIMMUNITY REVIEWS
- The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings
- (2020) Ross W Paterson et al. BRAIN
- COVID-19: Immunology and treatment options
- (2020) Susanna Felsenstein et al. CLINICAL IMMUNOLOGY
- Severe acute respiratory syndrome coronavirus‐2 may be an underappreciated pathogen of the central nervous system
- (2020) S.B. Alam et al. EUROPEAN JOURNAL OF NEUROLOGY
- The pathogenesis and treatment of the `Cytokine Storm' in COVID-19
- (2020) Qing Ye et al. JOURNAL OF INFECTION
- Central nervous system complications associated with SARS-CoV-2 infection: integrative concepts of pathophysiology and case reports
- (2020) Souhel Najjar et al. Journal of Neuroinflammation
- Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke
- (2020) Fadi Al Saiegh et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Neuronal ablation of IFNα/β signaling exacerbates CNS viral dissemination and impairs IFNγ responsiveness in microglia/macrophages
- (2020) Mihyun Hwang et al. JOURNAL OF VIROLOGY
- Neurological associations of COVID-19
- (2020) Mark A Ellul et al. LANCET NEUROLOGY
- COVID‐19–associated Guillain‐Barré syndrome: The early pandemic experience
- (2020) James B. Caress et al. MUSCLE & NERVE
- COVID-19 and the Immune System
- (2020) J PACES et al. PHYSIOLOGICAL RESEARCH
- Severe respiratory SARS-CoV2 infection: Does ACE2 receptor matter?
- (2020) Fabio Perrotta et al. RESPIRATORY MEDICINE
- Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
- (2020) Jérôme Hadjadj et al. SCIENCE
- Type III interferons disrupt the lung epithelial barrier upon viral recognition
- (2020) Achille Broggi et al. SCIENCE
- Immediate and long-term consequences of COVID-19 infections for the development of neurological disease
- (2020) Michael T. Heneka et al. Alzheimers Research & Therapy
- Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
- (2020) David H. Brann et al. Science Advances
- T cell engagement of cross-presenting microglia protects the brain from a nasal virus infection
- (2020) E. Ashley Moseman et al. Science Immunology
- Substance Use Disorder in the COVID-19 Pandemic: A Systematic Review of Vulnerabilities and Complications
- (2020) Yufeng Wei et al. Pharmaceuticals
- Covid-19 associated Guillain-Barre Syndrome: Contrasting tale of four patients from a tertiary care centre in India
- (2020) Satyan Nanda et al. AMERICAN JOURNAL OF EMERGENCY MEDICINE
- Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium
- (2020) Fadi Jacob et al. Cell Stem Cell
- SARS ‐CoV‐2 targets neurons of 3D human brain organoids
- (2020) Anand Ramani et al. EMBO JOURNAL
- Otolaryngological manifestations of hospitalised patients with confirmed COVID-19 infection
- (2020) Müge Özçelik Korkmaz et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Guillain–Barré syndrome spectrum associated with COVID-19: an up-to-date systematic review of 73 cases
- (2020) Samir Abu-Rumeileh et al. JOURNAL OF NEUROLOGY
- Convalescent plasma treatment of severe COVID-19: a propensity score–matched control study
- (2020) Sean T. H. Liu et al. NATURE MEDICINE
- Neurobiology of coronaviruses: Potential relevance for COVID-19
- (2020) Mauro Cataldi et al. NEUROBIOLOGY OF DISEASE
- Invited Review: The spectrum of neuropathology in COVID‐19
- (2020) S. Al‐Sarraj et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Immune profiling of COVID-19 patients
- (2020) Priscilla N. Kelly SCIENCE
- Autoantibodies against type I IFNs in patients with life-threatening COVID-19
- (2020) Paul Bastard et al. SCIENCE
- Evasion of Type I Interferon by SARS-CoV-2
- (2020) Hongjie Xia et al. Cell Reports
- Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies
- (2020) Wen Shi Lee et al. Nature Microbiology
- Anti–SARS-CoV-2 antibodies in the CSF, blood-brain barrier dysfunction, and neurological outcome
- (2020) Harry Alexopoulos et al. Neurology-Neuroimmunology & Neuroinflammation
- Detection of Viral Infections by Innate Immunity
- (2020) Michael Carty et al. BIOCHEMICAL PHARMACOLOGY
- Cerebrospinal fluid findings in neurological diseases associated with COVID-19 and insights into mechanisms of disease development
- (2020) Otávio Melo Espíndola et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
- (2020) Jenny Meinhardt et al. NATURE NEUROSCIENCE
- SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production
- (2020) Keli Chen et al. Viruses-Basel
- Shared and Distinct Functions of Type I and Type III Interferons
- (2019) Helen M. Lazear et al. IMMUNITY
- Lymphopenic community-acquired pneumonia is associated with a dysregulated immune response and increased severity and mortality
- (2019) Raúl Méndez et al. JOURNAL OF INFECTION
- The stimulation of thrombosis by hypoxia
- (2019) Neha Gupta et al. THROMBOSIS RESEARCH
- Interleukin-6 Expression by Hypothalamic Microglia in Multiple Inflammatory Contexts: A Systematic Review
- (2019) Vanessa C. D. Bobbo et al. Biomed Research International
- Type III interferons: Balancing tissue tolerance and resistance to pathogen invasion
- (2019) Achille Broggi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Dual microglia effects on blood brain barrier permeability induced by systemic inflammation
- (2019) Koichiro Haruwaka et al. Nature Communications
- Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease
- (2018) Jean-François Ghersi-Egea et al. ACTA NEUROPATHOLOGICA
- A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System
- (2018) Yan Qin et al. CELL
- Microglia are required for protection against lethal coronavirus encephalitis in mice
- (2018) D. Lori Wheeler et al. JOURNAL OF CLINICAL INVESTIGATION
- Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury
- (2018) Geoffrey T. Norris et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Axonal Transport Enables Neuron-to-Neuron propagation of HCoV-OC43
- (2018) Mathieu Dubé et al. JOURNAL OF VIROLOGY
- Brain-Resident T Cells Following Viral Infection
- (2018) Sujata Prasad et al. VIRAL IMMUNOLOGY
- Origin and evolution of pathogenic coronaviruses
- (2018) Jie Cui et al. NATURE REVIEWS MICROBIOLOGY
- CNS infection and immune privilege
- (2018) John V. Forrester et al. NATURE REVIEWS NEUROSCIENCE
- Tissue-resident memory T cells populate the human brain
- (2018) Joost Smolders et al. Nature Communications
- Fine Tuning the Cytokine Storm by IFN and IL-10 Following Neurotropic Coronavirus Encephalomyelitis
- (2018) Carine Savarin et al. Frontiers in Immunology
- Hepatitis E Virus Infects Neurons and Brains
- (2017) Xinying Zhou et al. JOURNAL OF INFECTIOUS DISEASES
- Chimeric antigen receptor T-cell therapy — assessment and management of toxicities
- (2017) Sattva S. Neelapu et al. Nature Reviews Clinical Oncology
- Physiological Effects of Chronic Hypoxia
- (2017) John B. West NEW ENGLAND JOURNAL OF MEDICINE
- The inner blood-retinal barrier: Cellular basis and development
- (2017) Mónica Díaz-Coránguez et al. VISION RESEARCH
- IL-6 ameliorates acute lung injury in influenza virus infection
- (2017) Mei-Lin Yang et al. Scientific Reports
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-inhibitor REDD1 in a STAT3-dependent manner
- (2016) Jessica Pinno et al. CELLULAR SIGNALLING
- HIF1α and metabolic reprogramming in inflammation
- (2016) Sarah E. Corcoran et al. JOURNAL OF CLINICAL INVESTIGATION
- Glial cell activation, recruitment, and survival of B-lineage cells following MCMV brain infection
- (2016) James R. Lokensgard et al. Journal of Neuroinflammation
- The Choroid Plexus in Healthy and Diseased Brain
- (2016) Charanjit Kaur et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Mechanisms of microglial activation in models of inflammation and hypoxia: Implications for chronic intermittent hypoxia
- (2016) Elizabeth A. Kiernan et al. JOURNAL OF PHYSIOLOGY-LONDON
- Guillain-Barré syndrome
- (2016) Hugh J Willison et al. LANCET
- A polarizing question: do M1 and M2 microglia exist?
- (2016) Richard M Ransohoff NATURE NEUROSCIENCE
- SARS and MERS: recent insights into emerging coronaviruses
- (2016) Emmie de Wit et al. NATURE REVIEWS MICROBIOLOGY
- Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study
- (2015) Gerardo Chowell et al. BMC Medicine
- Microglial M1/M2 polarization and metabolic states
- (2015) Ruben Orihuela et al. BRITISH JOURNAL OF PHARMACOLOGY
- Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4
- (2015) Kun Li et al. JOURNAL OF INFECTIOUS DISEASES
- Brain Invasion by Mouse Hepatitis Virus Depends on Impairment of Tight Junctions and Beta Interferon Production in Brain Microvascular Endothelial Cells
- (2015) Christian Bleau et al. JOURNAL OF VIROLOGY
- Viral Infection of the Central Nervous System and Neuroinflammation Precede Blood-Brain Barrier Disruption during Japanese Encephalitis Virus Infection
- (2015) Fang Li et al. JOURNAL OF VIROLOGY
- Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
- (2014) Yonit Lavin et al. CELL
- Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
- (2014) David Gosselin et al. CELL
- Critical Role for the NLRP3 Inflammasome during Acute Lung Injury
- (2014) J. J. Grailer et al. JOURNAL OF IMMUNOLOGY
- Associations Between Fibrin D-Dimer, Markers of Inflammation, Incident Self-Reported Mobility Limitation, and All-Cause Mortality in Older Men
- (2014) S. Goya Wannamethee et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Hypoxia Induces Autophagic Cell Death through Hypoxia-Inducible Factor 1α in Microglia
- (2014) Zhao Yang et al. PLoS One
- Anatomy, histochemistry, and immunohistochemistry of the olfactory subsystems in mice
- (2014) Arthur W. Barrios et al. Frontiers in Neuroanatomy
- Toll-Like Receptors 2, -3 and -4 Prime Microglia but not Astrocytes Across Central Nervous System Regions for ATP-Dependent Interleukin-1β Release
- (2014) Laura Facci et al. Scientific Reports
- Microglia Play a Major Role in Direct Viral-Induced Demyelination
- (2013) Dhriti Chatterjee et al. Clinical & Developmental Immunology
- Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology
- (2013) Sarah N. Lauder et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Microglia-mediated neuroinflammation is an amplifier of virus-induced neuropathology
- (2013) Jayasri Das Sarma JOURNAL OF NEUROVIROLOGY
- Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
- (2013) V. Stalin Raj et al. NATURE
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- Factors regulating microglia activation
- (2013) Katrin Kierdorf et al. Frontiers in Cellular Neuroscience
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Review: Activation patterns of microglia and their identification in the human brain
- (2012) D. Boche et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Understanding the T cell immune response in SARS coronavirus infection
- (2012) Hsueh-Ling Janice Oh et al. Emerging Microbes & Infections
- HIF and the Lung
- (2011) Larissa A. Shimoda et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
- (2011) Weibo Luo et al. CELL
- The Role of Microglia in the Healthy Brain
- (2011) M.-E. Tremblay et al. JOURNAL OF NEUROSCIENCE
- Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
- (2011) R. C. Paolicelli et al. SCIENCE
- PI3K/AKT/mTOR Pathway in Angiogenesis
- (2011) Jayashree Karar et al. Frontiers in Molecular Neuroscience
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Autocrine Interferon Priming in Macrophages but Not Dendritic Cells Results in Enhanced Cytokine and Chemokine Production after Coronavirus Infection
- (2010) H. Zhou et al. mBio
- The Systemic Inflammation of Alveolar Hypoxia Is Initiated by Alveolar Macrophage–Borne Mediator(s)
- (2009) Jie Chao et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2
- (2008) J. Netland et al. JOURNAL OF VIROLOGY
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