T cell engagement of cross-presenting microglia protects the brain from a nasal virus infection

Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function

(2019) Rebekah E. Dumm et al.   Nature Communications

CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis

(2019) Kristen E. Funk et al.   Journal of Neuroinflammation

T cells promote microglia-mediated synaptic elimination and cognitive dysfunction during recovery from neuropathogenic flaviviruses

(2019) Charise Garber et al.   NATURE NEUROSCIENCE

Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms

(2018) Rebeka Fekete et al.   ACTA NEUROPATHOLOGICA

Microglia are required for protection against lethal coronavirus encephalitis in mice

(2018) D. Lori Wheeler et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacologic depletion of microglia increases viral load in the brain and enhances mortality in murine models of Flavivirus-induced encephalitis

(2018) Scott Seitz et al.   JOURNAL OF VIROLOGY

North American domestic pigs are susceptible to experimental infection with Japanese encephalitis virus

(2018) So Lee Park et al.   Scientific Reports

Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage

(2018) Inken Waltl et al.   BRAIN BEHAVIOR AND IMMUNITY

Acute Viral Encephalitis

(2018) Kenneth L. Tyler   NEW ENGLAND JOURNAL OF MEDICINE

Inducible down-regulation of MHC class I results in natural killer cell tolerance

(2018) Michael D. Bern et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CNS infection and immune privilege

(2018) John V. Forrester et al.   NATURE REVIEWS NEUROSCIENCE

Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis

(2018) Chintan Chhatbar et al.   Cell Reports

Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus

(2017) D. Lori Wheeler et al.   JOURNAL OF VIROLOGY

A complement–microglial axis drives synapse loss during virus-induced memory impairment

(2016) Michael J. Vasek et al.   NATURE

Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells

(2015) Jasmin Herz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

(2015) Etsuo A Susaki et al.   Nature Protocols

Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest

(2015) Hélène D. Moreau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral diseases of the central nervous system

(2015) Phillip A Swanson et al.   Current Opinion in Virology

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

Long-term survival of influenza virus infected club cells drives immunopathology

(2014) Nicholas S. Heaton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The olfactory nerve: a shortcut for influenza and other viral diseases into the central nervous system

(2014) Debby van Riel et al.   JOURNAL OF PATHOLOGY

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Anatomy, histochemistry, and immunohistochemistry of the olfactory subsystems in mice

(2014) Arthur W. Barrios et al.   Frontiers in Neuroanatomy

Protective role of TNF-α, IL-10 and IL-2 in mice infected with the Oshima strain of Tick-borne encephalitis virus

(2014) Mya Myat Ngwe Tun et al.   Scientific Reports

Development of an Immunologically Tolerated Combination of Fluorescent Proteins for In vivo Two-photon Imaging

(2014) Selamawit Gossa et al.   Scientific Reports

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry

(2013) M. Shivkumar et al.   JOURNAL OF VIROLOGY

TNF-α Acts as an Immunoregulator in the Mouse Brain by Reducing the Incidence of Severe Disease Following Japanese Encephalitis Virus Infection

(2013) Daisuke Hayasaka et al.   PLoS One

B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity

(2012) E. Ashley Moseman et al.   IMMUNITY

The Multibasic Cleavage Site in H5N1 Virus Is Critical for Systemic Spread along the Olfactory and Hematogenous Routes in Ferrets

(2012) E. J. A. Schrauwen et al.   JOURNAL OF VIROLOGY

Comparison of Temporal and Spatial Dynamics of Seasonal H3N2, Pandemic H1N1 and Highly Pathogenic Avian Influenza H5N1 Virus Infections in Ferrets

(2012) Judith M. A. van den Brand et al.   PLoS One

Viral-induced encephalitis initiates distinct and functional CD103+ CD11b+ brain dendritic cell populations within the olfactory bulb

(2012) P. M. D'Agostino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Major histocompatibility complex class I proteins in brain development and plasticity

(2012) Bradford M. Elmer et al.   TRENDS IN NEUROSCIENCES

Neurons are MHC Class I-Dependent Targets for CD8 T Cells upon Neurotropic Viral Infection

(2011) Grégoire Chevalier et al.   PLoS Pathogens

Thinned-skull cranial window technique for long-term imaging of the cortex in live mice

(2010) Guang Yang et al.   Nature Protocols

Functional Anatomy of T Cell Activation and Synapse Formation

(2009) David R. Fooksman et al.   Annual Review of Immunology

Local Type I IFN Receptor Signaling Protects against Virus Spread within the Central Nervous System

(2009) C. N. Detje et al.   JOURNAL OF IMMUNOLOGY

Gamma Interferon Signaling in Macrophage Lineage Cells Regulates Central Nervous System Inflammation and Chemokine Production

(2009) A. A. Lin et al.   JOURNAL OF VIROLOGY

Noncytolytic Clearance of Sindbis Virus Infection from Neurons by Gamma Interferon Is Dependent on Jak/Stat Signaling

(2009) R. Burdeinick-Kerr et al.   JOURNAL OF VIROLOGY

Calcium signaling in lymphocytes

(2008) Masatsugu Oh-hora et al.   CURRENT OPINION IN IMMUNOLOGY

Tumor Necrosis Factor Alpha Protects against Lethal West Nile Virus Infection by Promoting Trafficking of Mononuclear Leukocytes into the Central Nervous System

(2008) B. Shrestha et al.   JOURNAL OF VIROLOGY

Noncytotoxic Lytic Granule-Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

(2008) J. E. Knickelbein et al.   SCIENCE

Neonatal and adult microglia cross-present exogenous antigens

(2007) Celine Beauvillain et al.   GLIA