Cell migration through three-dimensional confining pores: speed accelerations by deformation and recoil of the nucleus

Elevated nuclear lamin A is permissive for granulocyte transendothelial migration but not for motility through collagen I barriers

(2018) Sandeep Kumar Yadav et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Automated analysis of cell migration and nuclear envelope rupture in confined environments

(2018) Joshua J. Elacqua et al.   PLoS One

LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration

(2018) Elvira Infante et al.   Nature Communications

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

(2017) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

A Nanoprinted Model of Interstitial Cancer Migration Reveals a Link between Cell Deformability and Proliferation

(2016) Magdalini Panagiotakopoulou et al.   ACS Nano

Squish and squeeze — the nucleus as a physical barrier during migration in confined environments

(2016) Alexandra Lynn McGregor et al.   CURRENT OPINION IN CELL BIOLOGY

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells

(2016) Asier Jayo et al.   DEVELOPMENTAL CELL

Activating the nuclear piston mechanism of 3D migration in tumor cells

(2016) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

(2016) Hawa-Racine Thiam et al.   Nature Communications

Migration in Confined 3D Environments Is Determined by a Combination of Adhesiveness, Nuclear Volume, Contractility, and Cell Stiffness

(2015) Lena A. Lautscham et al.   BIOPHYSICAL JOURNAL

Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments

(2015) Patricia M. Davidson et al.   Integrative Biology

Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion

(2015) Dustin G. Thomas et al.   JOURNAL OF CELL BIOLOGY

Intracellular and extracellular domains of protein tyrosine phosphatase PTPRZ-B differentially regulate glioma cell growth and motility

(2015) Annika M. Bourgonje et al.   Oncotarget

Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor

(2015) Joshua M. Marcus et al.   Scientific Reports

In Situ Mechanical Characterization of the Cell Nucleus by Atomic Force Microscopy

(2014) Haijiao Liu et al.   ACS Nano

Actomyosin Pulls to Advance the Nucleus in a Migrating Tissue Cell

(2014) Jun Wu et al.   BIOPHYSICAL JOURNAL

Invading cancer cells are predominantly in G0/G1resulting in chemoresistance demonstrated by real-time FUCCI imaging

(2014) Shuya Yano et al.   CELL CYCLE

Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments

(2014) Patricia M. Davidson et al.   Cellular and Molecular Bioengineering

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Cellular mechanosensing: Getting to the nucleus of it all

(2014) Gregory R. Fedorchak et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Multifunctional polymer scaffolds with adjustable pore size and chemoattractant gradients for studying cell matrix invasion

(2013) Alexandra M. Greiner et al.   BIOMATERIALS

Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions

(2013) Amy C. Rowat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Probing the compressibility of tumor cell nuclei by combined atomic force–confocal microscopy

(2013) Marina Krause et al.   PHYSICAL BIOLOGY

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Nano-scale analyses of the chromatin decompaction induced by histone acetylation

(2012) Kohji Hizume et al.   ARCHIVES OF HISTOLOGY AND CYTOLOGY

Chromatin Decondensation and Nuclear Softening Accompany Nanog Downregulation in Embryonic Stem Cells

(2012) Kevin J. Chalut et al.   BIOPHYSICAL JOURNAL

Nuclear deformation during breast cancer cell transmigration

(2012) Yi Fu et al.   LAB ON A CHIP

Nuclear Morphometric Analysis (NMA): Screening of Senescence, Apoptosis and Nuclear Irregularities

(2012) Eduardo C. Filippi-Chiela et al.   PLoS One

Interlaboratory round robin on cantilever calibration for AFM force spectroscopy

(2011) Joost te Riet et al.   ULTRAMICROSCOPY

Amphibian oocyte nuclei expressing lamin A with the progeria mutation E145K exhibit an increased elastic modulus

(2011) Anna Kaufmann et al.   Nucleus

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Efficient cell migration requires global chromatin condensation

(2010) G. Gerlitz et al.   JOURNAL OF CELL SCIENCE

Dynamic changes in histone acetylation regulate origins of DNA replication

(2010) Ashwin Unnikrishnan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The role of chromatin structure in cell migration

(2010) Gabi Gerlitz et al.   TRENDS IN CELL BIOLOGY

Influence of Lamin A on the Mechanical Properties of Amphibian Oocyte Nuclei Measured by Atomic Force Microscopy

(2009) Jens Schäpe et al.   BIOPHYSICAL JOURNAL

Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6

(2009) Y. Zilberman et al.   JOURNAL OF CELL SCIENCE

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

Histone Modifications and Nuclear Architecture: A Review

(2008) Eva Bártová et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Stathmin Activity Influences Sarcoma Cell Shape, Motility, and Metastatic Potential

(2008) Barbara Belletti et al.   MOLECULAR BIOLOGY OF THE CELL

Paxillin Dynamics Measured during Adhesion Assembly and Disassembly by Correlation Spectroscopy

(2007) Michelle A. Digman et al.   BIOPHYSICAL JOURNAL