Dietary AGEs as Exogenous Boosters of Inflammation

Dicarbonyl stress, protein glycation and the unfolded protein response

(2021) Naila Rabbani et al.   GLYCOCONJUGATE JOURNAL

Processed foods drive intestinal barrier permeability and microvascular diseases

(2021) Matthew Snelson et al.   Science Advances

Inflammasome activation in podocytes: a new mechanism of glomerular diseases

(2020) Wei Xiong et al.   INFLAMMATION RESEARCH

The potential role of dietary advanced glycation endproducts in the development of chronic non-infectious diseases: a narrative review

(2020) M. E. Garay-Sevilla et al.   NUTRITION RESEARCH REVIEWS

Dietary advanced glycation end‐products: Perspectives linking food processing with health implications

(2020) Qiaozhi Zhang et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Loratadine Alleviates Advanced Glycation End Product-Induced Activation of NLRP3 Inflammasome in Human Chondrocytes

(2020) Feng Gao et al.   Drug Design Development and Therapy

The Mediterranean Diet: From an Environment-Driven Food Culture to an Emerging Medical Prescription

(2019) Cristina-Mihaela Lăcătușu et al.   International Journal of Environmental Research and Public Health

Dietary Advanced Glycation End Products: Digestion, Metabolism and Modulation of Gut Microbial Ecology

(2019) Matthew Snelson et al.   Nutrients

DASH Dietary Pattern and Cardiometabolic Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses

(2019) Laura Chiavaroli et al.   Nutrients

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Receptor for Advanced Glycation End Products (RAGE) and DIAPH1: Implications for vascular and neuroinflammatory dysfunction in disorders of the central nervous system

(2019) Michael MacLean et al.   NEUROCHEMISTRY INTERNATIONAL

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal

(2019) Zehra Irshad et al.   Scientific Reports

Western Diet and the Immune System: An Inflammatory Connection

(2019) Anette Christ et al.   IMMUNITY

Dietary Inflammatory Index and Non-Communicable Disease Risk: A Narrative Review

(2019) Catherine M. Phillips et al.   Nutrients

The Mediterranean Diet Slows Down the Progression of Aging and Helps to Prevent the Onset of Frailty: A Narrative Review

(2019) Cristiano Capurso et al.   Nutrients

Targeting RAGE Signaling in Inflammatory Disease

(2018) Barry I. Hudson et al.   Annual Review of Medicine

Dietary inflammatory index and cardiometabolic risk in US adults

(2018) Mohsen Mazidi et al.   ATHEROSCLEROSIS

Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

(2018) Ana Garcia-Arellano et al.   CLINICAL NUTRITION

The effect of dietary approaches to stop hypertension (DASH) on serum inflammatory markers: A systematic review and meta-analysis of randomized trials

(2018) Sepideh Soltani et al.   CLINICAL NUTRITION

Diet with high content of advanced glycation end products induces systemic inflammation and weight gain in experimental mice: Protective role of curcumin and gallic acid

(2018) Boopathi Sowndhar Rajan et al.   FOOD AND CHEMICAL TOXICOLOGY

Extracellular matrix as a driver of progressive fibrosis

(2018) Jeremy Herrera et al.   JOURNAL OF CLINICAL INVESTIGATION

Association between Dietary Inflammatory Index, C-Reactive Protein and Metabolic Syndrome: A Cross-Sectional Study

(2018) Zhongxia Ren et al.   Nutrients

Dietary Inflammatory Index and Cardiovascular Risk and Mortality—A Meta-Analysis

(2018) Nitin Shivappa et al.   Nutrients

RAGE and Its Ligands: Molecular Interplay Between Glycation, Inflammation, and Hallmarks of Cancer—a Review

(2018) Gowri Palanissami et al.   Hormones & Cancer

Mechanistic targeting of advanced glycation end-products in age-related diseases

(2018) Sheldon Rowan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inhibition of RAGE axis signaling: a pharmacological challenge.

(2018) Armando Rojas et al.   CURRENT DRUG TARGETS

THE DIETARY INFLAMMATORY INDEX AND INSULIN RESISTANCE OR METABOLIC SYNDROME IN YOUNG ADULTS

(2018) Carolina Carvalho   NUTRITION

Dietary Inflammatory Index and Biomarkers of Lipoprotein Metabolism, Inflammation and Glucose Homeostasis in Adults

(2018) Catherine Phillips et al.   Nutrients

The association between dietary inflammatory index and metabolic syndrome components in Iranian adults

(2018) Leila Nikniaz et al.   Primary Care Diabetes

Dietary advanced glycation end-product consumption leads to mechanical stiffening of murine intervertebral discs

(2018) Divya Krishnamoorthy et al.   Disease Models & Mechanisms

Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis

(2018) Raelene J. Pickering et al.   JOURNAL OF CLINICAL INVESTIGATION

Advanced glycation end products impair NLRP3 inflammasome–mediated innate immune responses in macrophages

(2017) Seunghwan Son et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary Advanced Glycation End Products Have Sex- and Age-Dependent Effects on Vertebral Bone Microstructure and Mechanical Function in Mice

(2017) Svenja Illien-Jünger et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective

(2017) Salvatore Bongarzone et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dietary Patterns and Type 2 Diabetes: A Systematic Literature Review and Meta-Analysis of Prospective Studies

(2017) Franziska Jannasch et al.   JOURNAL OF NUTRITION

Long-term administration of advanced glycation end-product stimulates the activation of NLRP3 inflammasome and sparking the development of renal injury

(2017) Wan-Ju Yeh et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Advanced glycation end products regulate interleukin-1β production in human placenta

(2017) Kotomi SENO et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Dietary fat quantity and quality modifies advanced glycation end products metabolism in patients with metabolic syndrome

(2017) Javier Lopez-Moreno et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

Regulatory landscape of AGE-RAGE-oxidative stress axis and its modulation by PPARγ activation in high fructose diet-induced metabolic syndrome

(2017) Luca Cannizzaro et al.   Nutrition & Metabolism

Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases

(2017) Kyunghee Byun et al.   PHARMACOLOGY & THERAPEUTICS

Origen, componentes y posibles mecanismos de acción de la dieta mediterránea

(2017) Inés Urquiaga et al.   REVISTA MEDICA DE CHILE

Effects of Two Different Dietary Patterns on Inflammatory Markers, Advanced Glycation End Products and Lipids in Subjects without Type 2 Diabetes: A Randomised Crossover Study

(2017) Yoona Kim et al.   Nutrients

Dietary Inflammatory Index and Colorectal Cancer Risk—A Meta-Analysis

(2017) Nitin Shivappa et al.   Nutrients

Advanced glycation end products dietary restriction effects on bacterial gut microbiota in peritoneal dialysis patients; a randomized open label controlled trial

(2017) Rabi Yacoub et al.   PLoS One

Consumption of diets with low advanced glycation end products improves cardiometabolic parameters: meta-analysis of randomised controlled trials

(2017) Estifanos Baye et al.   Scientific Reports

Identification of C1q as a Binding Protein for Advanced Glycation End Products

(2016) Miho Chikazawa et al.   BIOCHEMISTRY

Oral AGE restriction ameliorates insulin resistance in obese individuals with the metabolic syndrome: a randomised controlled trial

(2016) Helen Vlassara et al.   DIABETOLOGIA

Analysis of advanced glycation endproducts in selected food items by ultra-performance liquid chromatography tandem mass spectrometry: Presentation of a dietary AGE database

(2016) Jean L.J.M. Scheijen et al.   FOOD CHEMISTRY

Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities

(2016) Ilaria Russo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mediterranean Diet Reduces Serum Advanced Glycation End Products and Increases Antioxidant Defenses in Elderly Adults: A Randomized Controlled Trial

(2016) Javier Lopez-Moreno et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Quantitative assessment of organ distribution of dietary protein-bound13C-labeled Nɛ-carboxymethyllysine after a chronic oral exposure in mice

(2016) Frédéric J. Tessier et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The AGE-RAGE Axis and Its Relationship to Markers of Cardiovascular Disease in Newly Diagnosed Diabetic Patients

(2016) Ma. Etzabel Villegas-Rodríguez et al.   PLoS One

The Mediterranean Diet, its Components, and Cardiovascular Disease

(2015) R. Jay Widmer et al.   AMERICAN JOURNAL OF MEDICINE

Effects of the Dietary Approach to Stop Hypertension (DASH) diet on cardiovascular risk factors: a systematic review and meta-analysis

(2015) Mario Siervo et al.   BRITISH JOURNAL OF NUTRITION

Dietary inflammatory index and anthropometric measures of obesity in a population sample at high cardiovascular risk from the PREDIMED (PREvención con DIeta MEDiterránea) trial

(2015) M. Ruiz-Canela et al.   BRITISH JOURNAL OF NUTRITION

Low-grade inflammation, diet composition and health: current research evidence and its translation

(2015) Anne M. Minihane et al.   BRITISH JOURNAL OF NUTRITION

Dietary indexes, food patterns and incidence of metabolic syndrome in a Mediterranean cohort: The SUN project

(2015) Adriano M. Pimenta et al.   CLINICAL NUTRITION

Elevated Serum Advanced Glycation Endproducts in Obese Indicate Risk for the Metabolic Syndrome: A Link Between Healthy and Unhealthy Obesity?

(2015) Jaime Uribarri et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes

(2015) Aaron J. Fields et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Dietary CML-enriched protein induces functional arterial aging in a RAGE-dependent manner in mice

(2015) Nicolas Grossin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Benefits of the Mediterranean Diet: Insights From the PREDIMED Study

(2015) Miguel A. Martínez-González et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Soluble RAGEs — Prospects for treating & tracking metabolic and inflammatory disease

(2015) Ann Marie Schmidt   VASCULAR PHARMACOLOGY

Definition of the Mediterranean Diet; A Literature Review

(2015) Courtney Davis et al.   Nutrients

Dietary Advanced Glycation End Products and Their Role in Health and Disease

(2015) Jaime Uribarri et al.   Advances in Nutrition

Diet Quality as Assessed by the Healthy Eating Index, the Alternate Healthy Eating Index, the Dietary Approaches to Stop Hypertension Score, and Health Outcomes: A Systematic Review and Meta-Analysis of Cohort Studies

(2015) Lukas Schwingshackl et al.   Journal of the Academy of Nutrition and Dietetics

Chronic Ingestion of Advanced Glycation End Products Induces Degenerative Spinal Changes and Hypertrophy in Aging Pre-Diabetic Mice

(2015) Svenja Illien-Jünger et al.   PLoS One

Dietary advanced glycation end products are associated with decline in memory in young elderly

(2014) Rebecca K. West et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Role of advanced glycation end products in cellular signaling

(2014) Christiane Ott et al.   Redox Biology

Suppression of native defense mechanisms, SIRT1 and PPARγ, by dietary glycoxidants precedes disease in adult humans; relevance to lifestyle-engendered chronic diseases

(2013) Jaime Uribarri et al.   AMINO ACIDS

Advanced glycation end products in degenerative nucleus pulposus with diabetes

(2013) Tsung-Ting Tsai et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Glycation cross-linking induced mechanical–enzymatic cleavage of microscale tendon fibers

(2013) Jonathan W. Bourne et al.   MATRIX BIOLOGY

AGEs, rather than hyperglycemia, are responsible for microvascular complications in diabetes: A “glycoxidation-centric” point of view

(2013) N.C. Chilelli et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Combined Anti-Inflammatory and Anti-AGE Drug Treatments Have a Protective Effect on Intervertebral Discs in Mice with Diabetes

(2013) Svenja Illien-Junger et al.   PLoS One

Oligomerization Interface of RAGE Receptor Revealed by MS-Monitored Hydrogen Deuterium Exchange

(2013) Ewa Sitkiewicz et al.   PLoS One

Designing and developing a literature-derived, population-based dietary inflammatory index

(2013) Nitin Shivappa et al.   PUBLIC HEALTH NUTRITION

Metabolic transit of Nε-carboxymethyl-lysine after consumption of AGEs from bread crust

(2013) Irene Roncero-Ramos et al.   Food & Function

Dietary patterns, inflammation and the metabolic syndrome

(2012) N. Ahluwalia et al.   DIABETES & METABOLISM

Correlation of complement fragment C5a with inflammatory cytokines in the vitreous of patients with proliferative diabetic retinopathy

(2012) Daisuke Muramatsu et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The immunobiology of the receptor of advanced glycation end-products: Trends and challenges

(2012) Ileana González et al.   IMMUNOBIOLOGY

Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid beta 1-42-induced signal transduction in glial cells

(2012) Alexander Slowik et al.   Molecular Neurodegeneration

RAGE Expression in Human T Cells: A Link between Environmental Factors and Adaptive Immune Responses

(2012) Eitan M. Akirav et al.   PLoS One

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1

(2012) W. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of dietary bread crust Maillard reaction products on calcium and bone metabolism in rats

(2011) Irene Roncero-Ramos et al.   AMINO ACIDS

Skin Autofluorescence and the Association with Renal and Cardiovascular Risk Factors in Chronic Kidney Disease Stage 3

(2011) N. J. McIntyre et al.   Clinical Journal of the American Society of Nephrology

Restriction of Advanced Glycation End Products Improves Insulin Resistance in Human Type 2 Diabetes: Potential role of AGER1 and SIRT1

(2011) J. Uribarri et al.   DIABETES CARE

AGE restriction in diabetes mellitus: a paradigm shift

(2011) Helen Vlassara et al.   Nature Reviews Endocrinology

TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding

(2011) Masakiyo Sakaguchi et al.   PLoS One

Associations of Serum Levels of Advanced Glycation end Products with Nutrition Markers and Anemia in Patients with Chronic Kidney Disease

(2011) Markéta Kratochvilová et al.   RENAL FAILURE

Glyoxalase in ageing

(2011) Mingzhan Xue et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Multiphoton spectral microscopy for imaging and quantification of tissue glycation

(2011) Jo-Ya Tseng et al.   Biomedical Optics Express

A diet based on high-heat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases

(2010) Inès Birlouez-Aragon et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Reduction in the Incidence of Type 2 Diabetes With the Mediterranean Diet: Results of the PREDIMED-Reus nutrition intervention randomized trial

(2010) J. Salas-Salvado et al.   DIABETES CARE

Advanced Glycation End Products in Foods and a Practical Guide to Their Reduction in the Diet

(2010) Jaime Uribarri et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Structural Basis for Ligand Recognition and Activation of RAGE

(2010) Michael Koch et al.   STRUCTURE

Effect of Mediterranean diet on the expression of pro-atherogenic genes in a population at high cardiovascular risk

(2009) Vicenta Llorente-Cortés et al.   ATHEROSCLEROSIS

Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications

(2009) A. Bierhaus et al.   DIABETOLOGIA

A New Dietary Inflammatory Index Predicts Interval Changes in Serum High-Sensitivity C-Reactive Protein

(2009) Philip P. Cavicchia et al.   JOURNAL OF NUTRITION

RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation

(2009) Louis J Sparvero et al.   Journal of Translational Medicine

Effect of a Mediterranean Diet Supplemented With Nuts on Metabolic Syndrome Status

(2008) Jordi Salas-Salvadó   ARCHIVES OF INTERNAL MEDICINE

A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

(2008) Angela Raucci et al.   FASEB JOURNAL

Interaction of the RAGE Cytoplasmic Domain with Diaphanous-1 Is Required for Ligand-stimulated Cellular Migration through Activation of Rac1 and Cdc42

(2008) Barry I. Hudson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nɛ-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response

(2008) Timo M. Buetler et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Identification, classification, and expression of RAGE gene splice variants

(2007) Barry I. Hudson et al.   FASEB JOURNAL