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Title
Unlocking G-Quadruplexes as Antiviral Targets
Authors
Keywords
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Journal
PHARMACOLOGICAL REVIEWS
Volume 73, Issue 3, Pages 897-923
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Online
2021-05-28
DOI
10.1124/pharmrev.120.000230
References
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Note: Only part of the references are listed.- Analyses of viral genomes for G-quadruplex forming sequences reveal their correlation with the type of infection
- (2021) Natália Bohálová et al. BIOCHIMIE
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- (2020) Lauren L. Prister et al. BIOCHEMISTRY
- EGR1 Transcription Factor is a Multifaceted Regulator of Matrix Production in Tendons and Other Connective Tissues
- (2020) Emmanuelle Havis et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A guide to computational methods for G-quadruplex prediction
- (2020) Emilia Puig Lombardi et al. NUCLEIC ACIDS RESEARCH
- G2-quadruplex in the 3’UTR of IE180 regulates Pseudorabies Virus replication by enhancing gene expression
- (2020) Ya-Shu Zhang et al. RNA Biology
- Refining our methodologies for assessing quadruplex DNA ligands; selectivity or an illusion of selectivity?
- (2020) Akbar Amjadi Oskouie et al. ANALYTICAL BIOCHEMISTRY
- Conserved associations between G-quadruplex-forming DNA motifs and virulence gene families in malaria parasites
- (2020) Hunter L. Gage et al. BMC GENOMICS
- Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model
- (2020) Martina Tassinari et al. NUCLEIC ACIDS RESEARCH
- G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies
- (2020) Josué Carvalho et al. TRENDS IN MOLECULAR MEDICINE
- Discovery of G-quadruplex-forming sequences in SARS-CoV-2
- (2020) Danyang Ji et al. BRIEFINGS IN BIOINFORMATICS
- Epigenetic Modulation of Chromatin States and Gene Expression by G-Quadruplex Structures
- (2020) Chiara Reina et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The pathogenesis and treatment of the `Cytokine Storm' in COVID-19
- (2020) Qing Ye et al. JOURNAL OF INFECTION
- The chromatin landscape at the HIV-1 provirus integration site determines viral expression
- (2020) Gerlinde Vansant et al. NUCLEIC ACIDS RESEARCH
- Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites
- (2020) Elodie Gazanion et al. PLoS Genetics
- In-Depth Bioinformatic Analyses of Nidovirales Including Human SARS-CoV-2, SARS-CoV, MERS-CoV Viruses Suggest Important Roles of Non-canonical Nucleic Acid Structures in Their Lifecycles
- (2020) Martin Bartas et al. Frontiers in Microbiology
- Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells
- (2020) Jennifer Beauvarlet et al. Cancers
- Targeting RNA G‐quadruplex in SARS‐CoV‐2: A Promising Therapeutic Target for COVID‐19?
- (2020) Xiaogang Qu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- G-Quadruplexes in the Archaea Domain
- (2020) Václav Brázda et al. Biomolecules
- The Emerging Roles of TERRA in Telomere Maintenance and Genome Stability
- (2019) Nicole Bettin et al. Cells
- Characterization of highly conserved G-quadruplex motifs as potential drug targets in Streptococcus pneumoniae
- (2019) Subodh Kumar Mishra et al. Scientific Reports
- The Role of Marek’s Disease Virus UL12 and UL29 in DNA Recombination and the Virus Lifecycle
- (2019) Renato Previdelli et al. Viruses-Basel
- Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells
- (2019) Jennifer Beauvarlet et al. NUCLEIC ACIDS RESEARCH
- G-quadruplexes may determine the landscape of recombination in HSV-1
- (2019) Nandhini Saranathan et al. BMC GENOMICS
- Novel cationic Bis(acylhydrazones) as modulators of Epstein–Barr virus immune evasion acting through disruption of interaction between nucleolin and G-quadruplexes of EBNA1 mRNA
- (2019) Oksana Reznichenko et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Towards Understanding of Polymorphism of the G-rich Region of Human Papillomavirus Type 52
- (2019) Maja Marušič et al. MOLECULES
- Long-term Outcomes of Patients With Human Herpesvirus 6 Encephalitis
- (2019) Madiha Fida et al. Open Forum Infectious Diseases
- DNA G‐quadruplex stability, position and chromatin accessibility are associated with CpG island methylation
- (2019) Manuel Jara‐Espejo et al. FEBS Journal
- AS1411 derivatives as carriers of G-quadruplex ligands for cervical cancer cells
- (2019) Joana Figueiredo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- G-Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy
- (2018) Rafael del Villar-Guerra et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein
- (2018) Jian Lei et al. ANTIVIRAL RESEARCH
- G-quadruplex virtual drug screening: A review
- (2018) Robert C. Monsen et al. BIOCHIMIE
- The MYC oncogene is a global regulator of the immune response
- (2018) Stephanie C. Casey et al. BLOOD
- Influenza A Virus Infection Triggers Pyroptosis and Apoptosis of Respiratory Epithelial Cells through the Type I Interferon Signaling Pathway in a Mutually Exclusive Manner
- (2018) SangJoon Lee et al. JOURNAL OF VIROLOGY
- G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
- (2018) Emanuela Ruggiero et al. NUCLEIC ACIDS RESEARCH
- OUP accepted manuscript
- (2018) NUCLEIC ACIDS RESEARCH
- Pac1 Signals of Human Herpesviruses Contain a Highly Conserved G-Quadruplex Motif
- (2018) Banhi Biswas et al. ACS Infectious Diseases
- A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety
- (2018) Martina Tassinari et al. MOLECULES
- DNA G-quadruplex structures mold the DNA methylome
- (2018) Shi-Qing Mao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle
- (2018) Hasan Imam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- G-Quadruplexes: More Than Just a Kink in Microbial Genomes
- (2018) Nandhini Saranathan et al. TRENDS IN MICROBIOLOGY
- Genome-wide analysis of regulatory G-quadruplexes affecting gene expression in human cytomegalovirus
- (2018) Subramaniyam Ravichandran et al. PLoS Pathogens
- A Minimal Sequence for Left-Handed G-Quadruplex Formation
- (2018) Blaž Bakalar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop
- (2018) Elena Butovskaya et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication
- (2018) Wen-Xiu Bian et al. NUCLEIC ACIDS RESEARCH
- Identification of phlebovirus and arenavirus RNA sequences that stall and repress the exoribonuclease XRN1
- (2017) Phillida A. Charley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stabilization of Telomere G-Quadruplexes Interferes with Human Herpesvirus 6A Chromosomal Integration
- (2017) Shella Gilbert-Girard et al. JOURNAL OF VIROLOGY
- A G-quadruplex motif in an envelope gene promoter regulates transcription and virion secretion in HBV genotype B
- (2017) Banhi Biswas et al. NUCLEIC ACIDS RESEARCH
- Guanine quadruplex monoclonal antibody 1H6 cross-reacts with restrained thymidine-rich single stranded DNA
- (2017) Hinke G. Kazemier et al. NUCLEIC ACIDS RESEARCH
- Multimerization rules for G-quadruplexes
- (2017) Sofia Kolesnikova et al. NUCLEIC ACIDS RESEARCH
- Functional RNA during Zika virus infection
- (2017) Giel P. Göertz et al. VIRUS RESEARCH
- CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
- (2017) Hong Xu et al. Nature Communications
- The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes
- (2017) Matteo Scalabrin et al. Scientific Reports
- Genome-wide analysis of G-quadruplexes in herpesvirus genomes
- (2016) Banhi Biswas et al. BMC GENOMICS
- Visualization of DNA G-quadruplexes in herpes simplex virus 1-infected cells
- (2016) Sara Artusi et al. NUCLEIC ACIDS RESEARCH
- G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV
- (2016) Advaitha Madireddy et al. NUCLEIC ACIDS RESEARCH
- Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome
- (2016) Beatrice De Nicola et al. NUCLEIC ACIDS RESEARCH
- Re-evaluation of G-quadruplex propensity with G4Hunter
- (2016) Amina Bedrat et al. NUCLEIC ACIDS RESEARCH
- Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells
- (2016) Guangtong Zhou et al. Oncotarget
- Zika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae Family
- (2016) Aaron M. Fleming et al. ACS Infectious Diseases
- A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target
- (2016) S.-R. Wang et al. Science Advances
- Relationship of VEGF/VEGFR with immune and cancer cells: staggering or forward?
- (2016) Yu-Ling Li et al. Cancer Biology & Medicine
- The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand
- (2015) Sara Artusi et al. ANTIVIRAL RESEARCH
- Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-Quadruplexes
- (2015) Rosalba Perrone et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription
- (2015) Elena Tosoni et al. NUCLEIC ACIDS RESEARCH
- Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo
- (2015) Kyotaro Hirashima et al. NUCLEIC ACIDS RESEARCH
- HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter
- (2015) Filippo Turrini et al. Retrovirology
- A G-quadruplex-binding macrodomain within the “SARS-unique domain” is essential for the activity of the SARS-coronavirus replication–transcription complex
- (2015) Yuri Kusov et al. VIROLOGY
- G-Quadruplexes in Pathogens: A Common Route to Virulence Control?
- (2015) Lynne M. Harris et al. PLoS Pathogens
- TMPyP4, a Stabilizer of Nucleic Acid Secondary Structure, Is a Novel Acetylcholinesterase Inhibitor
- (2015) Nana Fujiwara et al. PLoS One
- Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
- (2014) Bradley Croy Doak et al. CHEMISTRY & BIOLOGY
- HIF Transcription Factors, Inflammation, and Immunity
- (2014) Asis Palazon et al. IMMUNITY
- Anti-HIV-1 activity of the G-quadruplex ligand BRACO-19
- (2014) R. Perrone et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- MoD-QM/MM Structural Refinement Method: Characterization of Hydrogen Bonding in the Oxytricha nova G-Quadruplex
- (2014) Junming Ho et al. Journal of Chemical Theory and Computation
- IgH Chain Class Switch Recombination: Mechanism and Regulation
- (2014) Janet Stavnezer et al. JOURNAL OF IMMUNOLOGY
- Topology of a DNA G-Quadruplex Structure Formed in the HIV-1 Promoter: A Potential Target for Anti-HIV Drug Development
- (2014) Samir Amrane et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- G-quadruplexes regulate Epstein-Barr virus–encoded nuclear antigen 1 mRNA translation
- (2014) Pierre Murat et al. Nature Chemical Biology
- G-quadruplexes in viruses: function and potential therapeutic applications
- (2014) Mathieu Métifiot et al. NUCLEIC ACIDS RESEARCH
- DNA G-quadruplex and its potential as anticancer drug target
- (2014) Buket Onel et al. Science China-Chemistry
- Getting away with murder: how does the BCL-2 family of proteins kill with immunity?
- (2013) Thibaud T. Renault et al. Annals of the New York Academy of Sciences
- Human Papillomavirus G-Quadruplexes
- (2013) Katarína Tlučková et al. BIOCHEMISTRY
- Silence, activate, poise and switch! Mechanisms of antigenic variation inPlasmodium falciparum
- (2013) Julien Guizetti et al. CELLULAR MICROBIOLOGY
- Mechanism of HIV-1 RNA Dimerization in the Central Region of the Genome and Significance for Viral Evolution
- (2013) Dorota Piekna-Przybylska et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Dynamic G-Quadruplex Region Regulates the HIV-1 Long Terminal Repeat Promoter
- (2013) Rosalba Perrone et al. JOURNAL OF MEDICINAL CHEMISTRY
- HIV-1 Nucleocapsid Proteins as Molecular Chaperones for Tetramolecular Antiparallel G-Quadruplex Formation
- (2013) Arivazhagan Rajendran et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Quantitative visualization of DNA G-quadruplex structures in human cells
- (2013) Giulia Biffi et al. Nature Chemistry
- Induction of RET Dependent and Independent Pro-Inflammatory Programs in Human Peripheral Blood Mononuclear Cells from Hirschsprung Patients
- (2013) Marta Rusmini et al. PLoS One
- Formation of a Unique Cluster of G-Quadruplex Structures in the HIV-1 nef Coding Region: Implications for Antiviral Activity
- (2013) Rosalba Perrone et al. PLoS One
- G-quadruplex structures are stable and detectable in human genomic DNA
- (2013) Enid Yi Ni Lam et al. Nature Communications
- A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress
- (2012) Pei-Chi Wei et al. NUCLEIC ACIDS RESEARCH
- G4LDB: a database for discovering and studying G-quadruplex ligands
- (2012) Qian Li et al. NUCLEIC ACIDS RESEARCH
- An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies
- (2011) Florian Hamon et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures
- (2011) Phong Lan Thao Tran et al. BIOCHIMIE
- Signaling of c-kit in dendritic cells influences adaptive immunity
- (2010) Prabir Ray et al. Annals of the New York Academy of Sciences
- ISG15 and immune diseases
- (2010) Young Joo Jeon et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth
- (2010) Denis Drygin et al. CANCER RESEARCH
- Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases
- (2009) Xiaoyu Hu et al. IMMUNITY
- Role for G-Quadruplex RNA Binding by Epstein-Barr Virus Nuclear Antigen 1 in DNA Replication and Metaphase Chromosome Attachment
- (2009) J. Norseen et al. JOURNAL OF VIROLOGY
- Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression
- (2009) Himesh Fernando et al. NUCLEIC ACIDS RESEARCH
- Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad
- (2009) Kah Wai Lim et al. NUCLEIC ACIDS RESEARCH
- EBNA1 regulates cellular gene expression by binding cellular promoters
- (2009) Allon Canaan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Alternative DNA Structure Is Necessary for Pilin Antigenic Variation in Neisseria gonorrhoeae
- (2009) L. A. Cahoon et al. SCIENCE
- G-quadruplex structures: in vivo evidence and function
- (2009) Hans J. Lipps et al. TRENDS IN CELL BIOLOGY
- The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes
- (2009) Jinzhi Tan et al. PLoS Pathogens
- Simian Virus 40 Large T-Antigen G-Quadruplex DNA Helicase Inhibition by G-Quadruplex DNA-Interactive Agents†
- (2008) Bodin Tuesuwan et al. BIOCHEMISTRY
- Real-time Investigation of SV40 Large T-antigen Helicase Activity Using Surface Plasmon Resonance
- (2008) Jason Plyler et al. CELL BIOCHEMISTRY AND BIOPHYSICS
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