Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome

The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand

(2015) Sara Artusi et al.   ANTIVIRAL RESEARCH

Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-Quadruplexes

(2015) Rosalba Perrone et al.   JOURNAL OF MEDICINAL CHEMISTRY

Characterization of DNA G-quadruplex species forming from C9ORF72 G4C2-expanded repeats associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration

(2015) Primož Šket et al.   NEUROBIOLOGY OF AGING

Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription

(2015) Elena Tosoni et al.   NUCLEIC ACIDS RESEARCH

Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G·G·X·O tetrad

(2015) Vee Vee Cheong et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

U3 Region in the HIV-1 Genome Adopts a G-Quadruplex Structure in Its RNA and DNA Sequence

(2014) Dorota Piekna-Przybylska et al.   BIOCHEMISTRY

Anti-HIV-1 activity of the G-quadruplex ligand BRACO-19

(2014) R. Perrone et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Topology of a DNA G-Quadruplex Structure Formed in the HIV-1 Promoter: A Potential Target for Anti-HIV Drug Development

(2014) Samir Amrane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neurodegenerative diseases: G-quadruplex poses quadruple threat

(2014) J. Paul Taylor   NATURE

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

(2014) Aaron R. Haeusler et al.   NATURE

G-quadruplexes regulate Epstein-Barr virus–encoded nuclear antigen 1 mRNA translation

(2014) Pierre Murat et al.   Nature Chemical Biology

G-quadruplexes in viruses: function and potential therapeutic applications

(2014) Mathieu Métifiot et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments

(2014) Pavel Ivanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Human Telomeric RNA (TERRA): Stacking of Two G-Quadruplex Blocks in K+ Solution

(2013) Herry Martadinata et al.   BIOCHEMISTRY

Human Papillomavirus G-Quadruplexes

(2013) Katarína Tlučková et al.   BIOCHEMISTRY

A Dynamic G-Quadruplex Region Regulates the HIV-1 Long Terminal Repeat Promoter

(2013) Rosalba Perrone et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bulges in G-Quadruplexes: Broadening the Definition of G-Quadruplex-Forming Sequences

(2013) Vineeth Thachappilly Mukundan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Detection of G-quadruplex DNA in mammalian cells

(2013) A. Henderson et al.   NUCLEIC ACIDS RESEARCH

G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold

(2013) Maja Marušič et al.   NUCLEIC ACIDS RESEARCH

Formation of a Unique Cluster of G-Quadruplex Structures in the HIV-1 nef Coding Region: Implications for Antiviral Activity

(2013) Rosalba Perrone et al.   PLoS One

Establishment and molecular mechanisms of HIV-1 latency in T cells

(2013) Renée M van der Sluis et al.   Current Opinion in Virology

A G-Rich element forms a G-quadruplex and regulates BACE1 mRNA alternative splicing

(2012) Jean-François Fisette et al.   JOURNAL OF NEUROCHEMISTRY

An AP-1 Binding Site in the Enhancer/Core Element of the HIV-1 Promoter Controls the Ability of HIV-1 To Establish Latent Infection

(2012) A. Duverger et al.   JOURNAL OF VIROLOGY

C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes

(2012) Pietro Fratta et al.   Scientific Reports

The evolving world of protein-G-quadruplex recognition: A medicinal chemist’s perspective

(2011) Claudia Sissi et al.   BIOCHIMIE

G-quadruplex-induced instability during leading-strand replication

(2011) Judith Lopes et al.   EMBO JOURNAL

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

G-quadruplex nucleic acids and human disease

(2010) Yuliang Wu et al.   FEBS Journal

Design of a G-Quadruplex Topology through Glycosidic Bond Angles

(2009) Mateus Webba da Silva et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Human telomeric G-quadruplex: structures of DNA and RNA sequences

(2009) Anh Tuân Phan   FEBS Journal

GiardiaTelomeric Sequence d(TAGGG)4Forms Two Intramolecular G-Quadruplexes in K+Solution: Effect of Loop Length and Sequence on the Folding Topology

(2009) Lanying Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role for G-Quadruplex RNA Binding by Epstein-Barr Virus Nuclear Antigen 1 in DNA Replication and Metaphase Chromosome Attachment

(2009) J. Norseen et al.   JOURNAL OF VIROLOGY

The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts

(2009) S. Nakken et al.   NUCLEIC ACIDS RESEARCH

Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells

(2009) Anjali Verma et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Analyses of Recombination Prone Regions Predict Role of DNA Structural Motif in Recombination

(2009) Prithvi Mani et al.   PLoS One

The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes

(2009) Jinzhi Tan et al.   PLoS Pathogens

Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes

(2008) Johanna Eddy et al.   NUCLEIC ACIDS RESEARCH

Stability and kinetics of G-quadruplex structures

(2008) A. N. Lane et al.   NUCLEIC ACIDS RESEARCH