Epigenetic Modulation of Chromatin States and Gene Expression by G-Quadruplex Structures

Destabilisation of the c-kit1 G-quadruplex structure by N6-methyladenosine modification

(2020) Saowalak Laddachote et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RNA G-quadruplex regulates microRNA-26a biogenesis and function

(2020) Geng Liu et al.   JOURNAL OF HEPATOLOGY

DNA:RNA hybrid G-quadruplex formation upstream of transcription start site

(2020) Jia-yu Zhang et al.   Scientific Reports

Histones, Their Variants and Post-translational Modifications in Zebrafish Development

(2020) Vincenzo Cavalieri   Frontiers in Cell and Developmental Biology

DNA Quadruple Helices in Nanotechnology

(2019) Jean-Louis Mergny et al.   CHEMICAL REVIEWS

Impact of Oxidative Lesions on the Human Telomeric G-quadruplex

(2019) Stasė Bielskutė et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mapping and characterization of G-quadruplexes in the genome of the social amoeba Dictyostelium discoideum

(2019) Mona Saad et al.   NUCLEIC ACIDS RESEARCH

Whole genome experimental maps of DNA G-quadruplexes in multiple species

(2019) Giovanni Marsico et al.   NUCLEIC ACIDS RESEARCH

Mycobacterium tuberculosis UvrD1 and UvrD2 helicases unwind G‐quadruplex DNA

(2019) Tias Saha et al.   FEBS Journal

Thermodynamically stable and genetically unstable G-quadruplexes are depleted in genomes across species

(2019) Emilia Puig Lombardi et al.   NUCLEIC ACIDS RESEARCH

RNA G-quadruplex is resolved by repetitive and ATP-dependent mechanism of DHX36

(2019) Ramreddy Tippana et al.   Nature Communications

Integrative characterization of G-Quadruplexes in the three-dimensional chromatin structure

(2019) Yue Hou et al.   Epigenetics

The diverse structural landscape of quadruplexes

(2019) Helen L. Lightfoot et al.   FEBS LETTERS

Human NEIL3 Gene Expression Regulated by Epigenetic-Like Oxidative DNA Modification

(2019) Aaron M. Fleming et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA G‐quadruplex stability, position and chromatin accessibility are associated with CpG island methylation

(2019) Manuel Jara‐Espejo et al.   FEBS Journal

Structure and Function of Multimeric G-Quadruplexes

(2019) Sofia Kolesnikova et al.   MOLECULES

G-tract RNA removes Polycomb repressive complex 2 from genes

(2019) Manuel Beltran et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DDX5 helicase resolves G-quadruplex and is involved in MYC gene transcriptional activation

(2019) Guanhui Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial role of two G-quadruplexes in 5′ UTR of transforming growth factor β2 (TGFβ2)

(2019) Prachi Agarwala et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor

(2019) Sanae Benabou et al.   Scientific Reports

Interplay of Guanine Oxidation and G-Quadruplex Folding in Gene Promoters

(2019) Aaron M. Fleming et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5′-Untranslated Regions

(2018) Aaron M. Fleming et al.   BIOCHEMISTRY

Perturbation of Developmental Regulatory Gene Expression by a G-Quadruplex DNA Inducer in the Sea Urchin Embryo

(2018) Giuseppina Turturici et al.   BIOCHEMISTRY

CpG Methylation Changes G-Quadruplex Structures Derived from Gene Promoters and Interaction with VEGF and SP1

(2018) Kaori Tsukakoshi et al.   MOLECULES

High-resolution AFM structure of DNA G-wires in aqueous solution

(2018) Krishnashish Bose et al.   Nature Communications

Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

(2018) Wenjing Hao et al.   Redox Biology

HMGB1 binds to the KRAS promoter G-quadruplex: a new player in oncogene transcriptional regulation?

(2018) Jussara Amato et al.   CHEMICAL COMMUNICATIONS

Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs

(2018) Ka Lung Chan et al.   CHEMICAL COMMUNICATIONS

RNA vs DNA G-Quadruplex: the origin of increased stability

(2018) Francesco Zaccaria et al.   CHEMISTRY-A EUROPEAN JOURNAL

DNA G-quadruplex structures mold the DNA methylome

(2018) Shi-Qing Mao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-wide analysis of regulatory G-quadruplexes affecting gene expression in human cytomegalovirus

(2018) Subramaniyam Ravichandran et al.   PLoS Pathogens

A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases

(2018) Andrew F. Voter et al.   Nature Communications

Transcriptome-wide identification of transient RNA G-quadruplexes in human cells

(2018) Sunny Y. Yang et al.   Nature Communications

A secondary structure within a human piRNA modulates its functionality

(2018) Sumirtha Balaratnam et al.   BIOCHIMIE

RNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF

(2017) Huilin Huang et al.   GENES & DEVELOPMENT

Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex–dependent fashion

(2017) Dhurjhoti Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of the human telomerase reverse transcriptase gene is modulated by quadruplex formation in its first exon due to DNA methylation

(2017) Pei-Tzu Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TET-mediated active DNA demethylation: mechanism, function and beyond

(2017) Xiaoji Wu et al.   NATURE REVIEWS GENETICS

Histone chaperone networks shaping chromatin function

(2017) Colin M. Hammond et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA

(2017) Xueyin Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

G-quadruplex structures within the 3′ UTR of LINE-1 elements stimulate retrotransposition

(2017) Aleksandr B Sahakyan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of human telomere RNA G-quadruplex structures in vitro and in living cells using 19F NMR spectroscopy

(2017) Hong-Liang Bao et al.   NUCLEIC ACIDS RESEARCH

The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

(2017) Susanna Cogoi et al.   NUCLEIC ACIDS RESEARCH

Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair

(2017) Aaron M. Fleming et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G-Quadruplexes influence pri-microRNA processing

(2017) Samuel G. Rouleau et al.   RNA Biology

A new cis -acting motif is required for the axonal SMN-dependent Anxa2 mRNA localization

(2017) Khalil Rihan et al.   RNA

Environmental epigenetics in zebrafish

(2017) Vincenzo Cavalieri et al.   Epigenetics & Chromatin

Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA

(2017) Xueyin Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

G-quadruplex structures within the 3′ UTR of LINE-1 elements stimulate retrotransposition

(2017) Aleksandr B Sahakyan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome

(2017) Fedor Kouzine et al.   Cell Systems

Transcription regulation of CDKN1A (p21/CIP1/WAF1) by TRF2 is epigenetically controlled through the REST repressor complex

(2017) Tabish Hussain et al.   Scientific Reports

Genome-wide analysis of G-quadruplexes in herpesvirus genomes

(2016) Banhi Biswas et al.   BMC GENOMICS

Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage

(2016) Yang Yu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

DNA G-quadruplexes show strong interaction with DNA methyltransferasesin vitro

(2016) Simone L. Cree et al.   FEBS LETTERS

TDP-43 binds and transports G-quadruplex-containing mRNAs into neurites for local translation

(2016) Akira Ishiguro et al.   GENES TO CELLS

Genome-wide regulatory dynamics of G-quadruplexes in human malaria parasite Plasmodium falciparum

(2016) Deeksha Bhartiya et al.   GENOMICS

Interaction of KRAS G-quadruplex with natural polyphenols: A spectroscopic analysis with molecular modeling

(2016) Rudradip Pattanayak et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression

(2016) Lang Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the Interactions of the Dietary Plant Flavonoids Fisetin and Naringenin with G-Quadruplex and Duplex DNA, Showing Contrasting Binding Behavior: Spectroscopic and Molecular Modeling Approaches

(2016) Snehasish Bhattacharjee et al.   JOURNAL OF PHYSICAL CHEMISTRY B

G-quadruplex structures mark human regulatory chromatin

(2016) Robert Hänsel-Hertsch et al.   NATURE GENETICS

Visualization of DNA G-quadruplexes in herpes simplex virus 1-infected cells

(2016) Sara Artusi et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme

(2016) Alexander Hirschi et al.   RNA

The Sea Urchinsns5Chromatin Insulator Shapes the Chromatin Architecture of a Lentivirus Vector Integrated in the Mammalian Genome

(2016) Elena Baiamonte et al.   Nucleic Acid Therapeutics

Zika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae Family

(2016) Aaron M. Fleming et al.   ACS Infectious Diseases

Metal Cations in G-Quadruplex Folding and Stability

(2016) Debmalya Bhattacharyya et al.   Frontiers in Chemistry

Genome-wide discovery of G-quadruplex forming sequences and their functional relevance in plants

(2016) Rohini Garg et al.   Scientific Reports

Human Telomere G-Quadruplexes with Five Repeats Accommodate 8-Oxo-7,8-dihydroguanine by Looping out the DNA Damage

(2015) Na An et al.   ACS Chemical Biology

An Independently Folding RNA G-Quadruplex Domain Directly Recruits the 40S Ribosomal Subunit

(2015) Debmalya Bhattacharyya et al.   BIOCHEMISTRY

The RNA Stem–Loop to G-Quadruplex Equilibrium Controls Mature MicroRNA Production inside the Cell

(2015) Satyaprakash Pandey et al.   BIOCHEMISTRY

A Potassium Ion-Dependent RNA Structural Switch Regulates Human Pre-miRNA 92b Maturation

(2015) Gayan Mirihana Arachchilage et al.   CHEMISTRY & BIOLOGY

Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites

(2015) A. Piazza et al.   EMBO JOURNAL

Characterizing and controlling intrinsic biases of lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication origins

(2015) Michael S. Foulk et al.   GENOME RESEARCH

G-quadruplexes: A possible epigenetic target for nutrition

(2015) Maxime François et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

High-throughput sequencing of DNA G-quadruplex structures in the human genome

(2015) Vicki S Chambers et al.   NATURE BIOTECHNOLOGY

Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications

(2015) Magdalena J Koziol et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres

(2015) Maheshi Udugama et al.   NUCLEIC ACIDS RESEARCH

Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo

(2015) Kyotaro Hirashima et al.   NUCLEIC ACIDS RESEARCH

Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase

(2015) Michael C. Chen et al.   NUCLEIC ACIDS RESEARCH

Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications

(2015) Magdalena J Koziol et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enhancer-promoter interaction facilitated by transiently forming G-quadruplexes

(2015) Hedi Hegyi   Scientific Reports

A Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These “Spare Tires” Have an Evolved Function?

(2015) Aaron M. Fleming et al.   ACS Central Science

Ectopic hbox12 Expression Evoked by Histone Deacetylase Inhibition Disrupts Axial Specification of the Sea Urchin Embryo

(2015) Vincenzo Cavalieri et al.   PLoS One

FMRP interacts with G-quadruplex structures in the 3’-UTR of its dendritic target Shank1 mRNA

(2015) Yang Zhang et al.   RNA Biology

Epigenetic Modification, Dehydration, and Molecular Crowding Effects on the Thermodynamics of i-Motif Structure Formation from C-Rich DNA

(2014) Yogini P. Bhavsar-Jog et al.   BIOCHEMISTRY

In the Sense of Transcription Regulation by G-Quadruplexes: Asymmetric Effects in Sense and Antisense Strands

(2014) Tani Agarwal et al.   BIOCHEMISTRY

Role of G-quadruplex located at 5ʹ end of mRNAs

(2014) Prachi Agarwala et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells

(2014) D. Schiavone et al.   EMBO JOURNAL

G4 motifs affect origin positioning and efficiency in two vertebrate replicators

(2014) A.-L. Valton et al.   EMBO JOURNAL

The clustering of CpG islands may constitute an important determinant of the 3D organization of interphase chromosomes

(2014) Ekaterina S Gushchanskaya et al.   Epigenetics

Topology of a DNA G-Quadruplex Structure Formed in the HIV-1 Promoter: A Potential Target for Anti-HIV Drug Development

(2014) Samir Amrane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational Transition of a Hairpin Structure to G-Quadruplex within the WNT1 Gene Promoter

(2014) Margaret Hsin-Jui Kuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA

(2014) Toni Pfaffeneder et al.   Nature Chemical Biology

G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD

(2014) Lucas T Gray et al.   Nature Chemical Biology

CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

G-Quadruplex Structures and CpG Methylation Cause Drop-Out of the Maternal Allele in Polymerase Chain Reaction Amplification of the Imprinted MEST Gene Promoter

(2014) Aaron J. Stevens et al.   PLoS One

Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone

(2014) U. M. Muthurajan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA

(2014) Ruobo Zhou et al.   eLife

Unusual −1 Ribosomal Frameshift Caused by Stable RNA G-Quadruplex in Open Reading Frame

(2013) Tamaki Endoh et al.   ANALYTICAL CHEMISTRY

Combination of i-Motif and G-Quadruplex Structures within the Same Strand: Formation and Application

(2013) Jun Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The G-Quadruplex Augments Translation in the 5′ Untranslated Region of Transforming Growth Factor β2

(2013) Prachi Agarwala et al.   BIOCHEMISTRY

G-Quadruplex conformational change driven by pH variation with potential application as a nanoswitch

(2013) Yi-Yong Yan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

(2013) Cornelia G. Spruijt et al.   CELL

Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS

(2013) Kentaro Takahama et al.   CHEMISTRY & BIOLOGY

The Disease-associated r(GGGGCC)nRepeat from theC9orf72Gene Forms Tract Length-dependent Uni- and Multimolecular RNA G-quadruplex Structures

(2013) Kaalak Reddy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FANCJ couples replication past natural fork barriers with maintenance of chromatin structure

(2013) Rebekka A. Schwab et al.   JOURNAL OF CELL BIOLOGY

A Dynamic G-Quadruplex Region Regulates the HIV-1 Long Terminal Repeat Promoter

(2013) Rosalba Perrone et al.   JOURNAL OF MEDICINAL CHEMISTRY

HIV-1 Nucleocapsid Proteins as Molecular Chaperones for Tetramolecular Antiparallel G-Quadruplex Formation

(2013) Arivazhagan Rajendran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bulges in G-Quadruplexes: Broadening the Definition of G-Quadruplex-Forming Sequences

(2013) Vineeth Thachappilly Mukundan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements

(2013) Giulia Antoniali et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Stimulation of ribosomal frameshifting by RNA G-quadruplex structures

(2013) Chien-Hung Yu et al.   NUCLEIC ACIDS RESEARCH

Detection of G-quadruplex DNA in mammalian cells

(2013) A. Henderson et al.   NUCLEIC ACIDS RESEARCH

Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals

(2013) Shan Xiao et al.   NUCLEIC ACIDS RESEARCH

Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control

(2013) Ke-wei Zheng et al.   NUCLEIC ACIDS RESEARCH

Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening

(2013) Jean-Denis Beaudoin et al.   NUCLEIC ACIDS RESEARCH

The Compass-like Locus, Exclusive to the Ambulacrarians, Encodes a Chromatin Insulator Binding Protein in the Sea Urchin Embryo

(2013) Vincenzo Cavalieri et al.   PLoS Genetics

The G4 Genome

(2013) Nancy Maizels et al.   PLoS Genetics

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

(2012) Omar Abdel-Wahab et al.   CANCER CELL

Genome-wide Studies of CCCTC-binding Factor (CTCF) and Cohesin Provide Insight into Chromatin Structure and Regulation: FIGURE 1.

(2012) Bum-Kyu Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure, function and targeting of human telomere RNA

(2012) Yan Xu et al.   METHODS

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Y-family DNA polymerases and their role in tolerance of cellular DNA damage

(2012) Julian E. Sale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

(2012) Emilie Besnard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

5'-UTR RNA G-quadruplexes: translation regulation and targeting

(2012) A. Bugaut et al.   NUCLEIC ACIDS RESEARCH

Potential G-quadruplexes in the human long non-coding transcriptome

(2012) Gopal Gunanathan Jayaraj et al.   RNA Biology

The high mobility group box: the ultimate utility player of a cell

(2012) Christopher S. Malarkey et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phenolic promiscuity in the cell nucleus – epigallocatechingallate (EGCG) and theaflavin-3,3′-digallate from green and black tea bind to model cell nuclear structures including histone proteins, double stranded DNA and telomeric quadruplex DNA

(2012) Gediminas Mikutis et al.   Food & Function

Effects of Site-Specific Guanine C8-Modifications on an Intramolecular DNA G-Quadruplex

(2011) Christopher Jacques Lech et al.   BIOPHYSICAL JOURNAL

G–quadruplex RNA structure as a signal for neurite mRNA targeting

(2011) Murugan Subramanian et al.   EMBO REPORTS

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

(2011) William A. Pastor et al.   NATURE

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

The insertion of two 8-methyl-2′-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands

(2011) Antonella Virgilio et al.   NUCLEIC ACIDS RESEARCH

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA

(2011) Peter Sarkies et al.   NUCLEIC ACIDS RESEARCH

Cellular nucleic-acid-binding protein, a transcriptional enhancer of c-Myc, promotes the formation of parallel G-quadruplexes

(2010) Mariana Borgognone et al.   BIOCHEMICAL JOURNAL

Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity

(2010) Cyril M. Sanders   BIOCHEMICAL JOURNAL

TheBCL-25′ Untranslated Region Contains an RNA G-Quadruplex-Forming Motif That Modulates Protein Expression

(2010) Ramla Shahid et al.   BIOCHEMISTRY

Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes

(2010) Phong Lan Thao Tran et al.   BIOCHIMIE

Structure, location and interactions of G-quadruplexes

(2010) Julian L. Huppert   FEBS Journal

TheKRASPromoter Responds to Myc-associated Zinc Finger and Poly(ADP-ribose) Polymerase 1 Proteins, Which Recognize a Critical Quadruplex-formingGA-element

(2010) Susanna Cogoi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An RNA G-Quadruplex Is Essential for Cap-Independent Translation Initiation in Human VEGF IRES

(2010) Mark J. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide

(2010) Rashi Halder et al.   Molecular BioSystems

Epigenetic Instability due to Defective Replication of Structured DNA

(2010) Peter Sarkies et al.   MOLECULAR CELL

Replication Stress Interferes with Histone Recycling and Predeposition Marking of New Histones

(2010) Zuzana Jasencakova et al.   MOLECULAR CELL

Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

(2010) Chun-Xiao Song et al.   NATURE BIOTECHNOLOGY

Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene

(2010) D. Sun et al.   NUCLEIC ACIDS RESEARCH

How long is too long? Effects of loop size on G-quadruplex stability

(2010) Aurore Guédin et al.   NUCLEIC ACIDS RESEARCH

A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells

(2010) Dennis Gomez et al.   NUCLEIC ACIDS RESEARCH

G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae

(2010) John A. Capra et al.   PLoS Computational Biology

An Unusually Stable G-Quadruplex within the 5′-UTR of the MT3 Matrix Metalloproteinase mRNA Represses Translation in Eukaryotic Cells

(2009) Mark J. Morris et al.   BIOCHEMISTRY

Regulation of chromatin structure and function By HMGN proteins

(2009) Yuri Postnikov et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A comparison of DNA and RNA quadruplex structures and stabilities

(2009) Astrid Joachimi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification and Characterization of Nucleolin as a c-mycG-quadruplex-binding Protein

(2009) Verónica González et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stable G-quadruplexes are found outside nucleosome-bound regions

(2009) Han Min Wong et al.   Molecular BioSystems

Genome-wide analysis predicts DNA structural motifs as nucleosome exclusion signals

(2009) Kangkan Halder et al.   Molecular BioSystems

Promoter activity of the sea urchin ( Paracentrotus lividus ) nucleosomal H3 and H2A and linker H1 α-histone genes is modulated by enhancer and chromatin insulator

(2009) Vincenzo Cavalieri et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression

(2009) Himesh Fernando et al.   NUCLEIC ACIDS RESEARCH

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

(2009) Cyril Ribeyre et al.   PLoS Genetics

Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes

(2008) Julian Leon Huppert   CHEMICAL SOCIETY REVIEWS

cis-Regulatory sequences driving the expression of the Hbox12 homeobox-containing gene in the presumptive aboral ectoderm territory of the Paracentrotus lividus sea urchin embryo

(2008) Vincenzo Cavalieri et al.   DEVELOPMENTAL BIOLOGY

Genome-Wide Computational and Expression Analyses Reveal G-Quadruplex DNA Motifs as Conservedcis-Regulatory Elements in Human and Related Species

(2008) Anjali Verma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Energetic and Hydration Contributions of the Removal of Methyl Groups From Thymine to Form Uracil in G-Quadruplexes

(2008) Chris M. Olsen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Effect of O6-Methylguanine on the Stability of G-Quadruplex DNA

(2008) Chongkham S. Mekmaysy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability

(2008) Y. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression

(2008) Ram Krishna Thakur et al.   NUCLEIC ACIDS RESEARCH

The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer

(2008) Marie-Cécile Didiot et al.   NUCLEIC ACIDS RESEARCH

Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif

(2008) A. Arora et al.   RNA

Antitumor activity of G-quadruplex–interactive agent TMPyP4 in K562 leukemic cells

(2007) Yoko Mikami-Terao et al.   CANCER LETTERS