Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells

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Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment

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RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms

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Chemical screening identifies ATM as a target for alleviating senescence

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DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential

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Repair, Reuse, Recycle: The Expanding Role of Autophagy in Genome Maintenance

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CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

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How autophagy both activates and inhibits cellular senescence

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Quadruplex Nucleic Acids as Novel Therapeutic Targets

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Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds

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DNA Damage Response and Autophagy: A Meaningful Partnership

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A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

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A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer

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ATM Couples Replication Stress and Metabolic Reprogramming during Cellular Senescence

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DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase

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Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage

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Induction of senescence in cancer cells by the G-quadruplex stabilizer, BMVC4, is independent of its telomerase inhibitory activity

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A G-quadruplex ligand SYUIQ-5 induces autophagy by inhibiting the Akt-FOXO3a pathway in nasopharyngeal cancer cells

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Unraveling the relationship between structure and stabilization of triarylpyridines as G-quadruplex binding ligands

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G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells

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