- Home
- Publications
- Publication Search
- Publication Details
Title
Nuclear cGAS: guard or prisoner?
Authors
Keywords
-
Journal
EMBO JOURNAL
Volume 40, Issue 16, Pages -
Publisher
EMBO
Online
2021-07-12
DOI
10.15252/embj.2021108293
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- ER-directed TREX1 limits cGAS activation at micronuclei
- (2021) Lisa Mohr et al. MOLECULAR CELL
- A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
- (2021) Hong Sun et al. Cell Reports
- cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing
- (2021) Wen Zhou et al. MOLECULAR CELL
- Phosphorylation and chromatin tethering prevent cGAS activation during mitosis
- (2021) Tuo Li et al. SCIENCE
- The cytosolic DNA sensor cGAS recognizes neutrophil extracellular traps
- (2021) Falko Apel et al. Science Signaling
- The structure of a virus-encoded nucleosome
- (2021) Marco Igor Valencia-Sánchez et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mesoscale organization of the chromatin fiber
- (2020) Nils Krietenstein et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Molecular mechanisms and cellular functions of cGAS–STING signalling
- (2020) Karl-Peter Hopfner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response
- (2020) Hongming Ma et al. mBio
- Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis
- (2020) Li Zhong et al. Cell Discovery
- Attenuation of cGAS/STING activity during mitosis
- (2020) Brittany L Uhlorn et al. Life Science Alliance
- Structural basis for nucleosome-mediated inhibition of cGAS activity
- (2020) Duanfang Cao et al. CELL RESEARCH
- The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS
- (2020) Baoyu Zhao et al. NATURE
- Structural basis for sequestration and autoinhibition of cGAS by chromatin
- (2020) Sebastian Michalski et al. NATURE
- Structural mechanism of cGAS inhibition by the nucleosome
- (2020) Ganesh R. Pathare et al. NATURE
- BAF restricts cGAS on nuclear DNA to prevent innate immune activation
- (2020) Baptiste Guey et al. SCIENCE
- Structural basis for the inhibition of cGAS by nucleosomes
- (2020) Tomoya Kujirai et al. SCIENCE
- Structural basis of nucleosome-dependent cGAS inhibition
- (2020) Joshua A. Boyer et al. SCIENCE
- cGAS suppresses genomic instability as a decelerator of replication forks
- (2020) Hao Chen et al. Science Advances
- cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing
- (2020) Carolina Uggenti et al. NATURE GENETICS
- Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5
- (2020) Shufang Cui et al. Cell Reports
- Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase
- (2019) Cathy J. Anderson et al. Cell Reports
- The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus
- (2019) Matteo Gentili et al. Cell Reports
- cGAS in action: Expanding roles in immunity and inflammation
- (2019) Andrea Ablasser et al. SCIENCE
- Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L
- (2019) Evan J. Worden et al. CELL
- The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death
- (2019) Christian Zierhut et al. CELL
- Mitotic Chromosome Mechanics: How Cells Segregate Their Genome
- (2019) Paul Batty et al. TRENDS IN CELL BIOLOGY
- Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death
- (2019) Hui Jiang et al. EMBO JOURNAL
- Tight nuclear tethering of cGAS is essential for preventing autoreactivity
- (2019) Hannah E Volkman et al. eLife
- A Transient Rise in Free Mg 2+ Ions Released from ATP-Mg Hydrolysis Contributes to Mitotic Chromosome Condensation
- (2018) Kazuhiro Maeshima et al. CURRENT BIOLOGY
- A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion
- (2018) Pengyan Xia et al. IMMUNITY
- Chromosomal instability drives metastasis through a cytosolic DNA response
- (2018) Samuel F. Bakhoum et al. NATURE
- DNA-induced liquid phase condensation of cGAS activates innate immune signaling
- (2018) Mingjian Du et al. SCIENCE
- Heterochromatin: Guardian of the Genome
- (2018) Aniek Janssen et al. Annual Review of Cell and Developmental Biology
- NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
- (2018) Xavier Lahaye et al. CELL
- Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
- (2018) Haipeng Liu et al. NATURE
- Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
- (2017) Kareen Bartsch et al. HUMAN MOLECULAR GENETICS
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Mitotic progression following DNA damage enables pattern recognition within micronuclei
- (2017) Shane M. Harding et al. NATURE
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
- (2017) Zhixun Dou et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- Ten principles of heterochromatin formation and function
- (2017) Robin C. Allshire et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- cGAS is essential for cellular senescence
- (2017) Hui Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- cGAS Conducts Micronuclei DNA Surveillance
- (2017) Carina C. de Oliveira Mann et al. TRENDS IN CELL BIOLOGY
- SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing
- (2017) Ye Cui et al. PLoS Pathogens
- Recognition of the nucleosome by chromatin factors and enzymes
- (2016) Robert K McGinty et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The structural basis of modified nucleosome recognition by 53BP1
- (2016) Marcus D. Wilson et al. NATURE
- Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers
- (2016) Petra Schwertman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances
- (2015) Marco Y. Hein et al. CELL
- Barrier to Autointegration Factor (BANF1): interwoven roles in nuclear structure, genome integrity, innate immunity, stress responses and progeria
- (2015) Augusta Jamin et al. CURRENT OPINION IN CELL BIOLOGY
- DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
- (2015) Anetta Härtlova et al. IMMUNITY
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- Genome Wide Nucleosome Mapping for HSV-1 Shows Nucleosomes Are Deposited at Preferred Positions during Lytic Infection
- (2015) Jaewook Oh et al. PLoS One
- cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection
- (2015) Megan H. Orzalli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units
- (2014) F. Song et al. SCIENCE
- The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
- (2014) Xu Zhang et al. Cell Reports
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
- (2013) Xin Li et al. IMMUNITY
- Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
- (2013) Xu Zhang et al. MOLECULAR CELL
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- Structural mechanism of cytosolic DNA sensing by cGAS
- (2013) Filiz Civril et al. NATURE
- Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
- (2013) Andrea Ablasser et al. NATURE
- Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
- (2012) J. Wu et al. SCIENCE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- Architecture of the high mobility group nucleosomal protein 2-nucleosome complex as revealed by methyl-based NMR
- (2011) H. Kato et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 A Resolution
- (2011) K.-J. Armache et al. SCIENCE
- Structure of RCC1 chromatin factor bound to the nucleosome core particle
- (2010) Ravindra D. Makde et al. NATURE
- Linker histone H1 is essential for Drosophila development, the establishment of pericentric heterochromatin, and a normal polytene chromosome structure
- (2009) X. Lu et al. GENES & DEVELOPMENT
- A Tale of Tails: How Histone Tails Mediate Chromatin Compaction in Different Salt and Linker Histone Environments†
- (2009) Gaurav Arya et al. JOURNAL OF PHYSICAL CHEMISTRY A
- ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
- (2009) W. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A–H2B acidic pocket
- (2008) Lucie Roussel et al. EMBO REPORTS
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly
- (2008) T. Haraguchi et al. JOURNAL OF CELL SCIENCE
- Chromatin organization and virus gene expression
- (2008) Paul M. Lieberman JOURNAL OF CELLULAR PHYSIOLOGY
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now