Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability

Iron Withholding: A Defense Against Disease

(2017) Eugene D. Weinberg et al.   JOURNAL OF ALZHEIMERS DISEASE

Drug Development Based on the Metals Hypothesis of Alzheimer's Disease

(2017) Ashley I. Bush   JOURNAL OF ALZHEIMERS DISEASE

Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment

(2017) Mark A. Smith et al.   JOURNAL OF ALZHEIMERS DISEASE

Is rheumatoid arthritis an autoimmune disease?

(2016) Karine Chemin et al.   CURRENT OPINION IN RHEUMATOLOGY

Serum proteomic analysis identifies interleukin 16 as a biomarker for clinical response during early treatment of rheumatoid arthritis

(2016) Atsuko Murota et al.   CYTOKINE

Biologics beyond TNF-αinhibitors and the effect of targeting the homologues TL1A-DR3 pathway in chronic inflammatory disorders

(2016) Peter Tougaard et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Role of interleukin-23 as a biomarker in rheumatoid arthritis patients and its correlation with disease activity

(2016) Doaa S.E. Zaky et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cardiovascular Comorbidities Relate More than Others with Disease Activity in Rheumatoid Arthritis

(2016) Gloria Crepaldi et al.   PLoS One

Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays

(2016) Yohei Hisada et al.   THROMBOSIS RESEARCH

An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis

(2016) Jun Chen et al.   Genome Medicine

Autoantibodies From Single Circulating Plasmablasts React With Citrullinated Antigens andPorphyromonas gingivalisin Rheumatoid Arthritis

(2016) Song Li et al.   Arthritis & Rheumatology

Antibodies toPorphyromonas gingivalisIndicate Interaction Between Oral Infection, Smoking, and Risk Genes in Rheumatoid Arthritis Etiology

(2016) Nastya Kharlamova et al.   Arthritis & Rheumatology

Key Points Concerning Amyloid Infectivity and Prion-Like Neuronal Invasion

(2016) Alba Espargaró et al.   Frontiers in Molecular Neuroscience

Periodontitis is associated with rheumatoid arthritis: a study with longstanding rheumatoid arthritis patients in Korea

(2016) In Ah Choi et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Hand to Mouth: A Systematic Review and Meta-Analysis of the Association between Rheumatoid Arthritis and Periodontitis

(2016) Nicholas R. Fuggle et al.   Frontiers in Immunology

IL-6 inhibitors for treatment of rheumatoid arthritis: past, present, and future

(2015) Go Woon Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

IL-27-induced modulation of autoimmunity and its therapeutic potential

(2015) Rakeshchandra R. Meka et al.   AUTOIMMUNITY REVIEWS

Prevention of cardiovascular disease in rheumatoid arthritis

(2015) I. Hollan et al.   AUTOIMMUNITY REVIEWS

Co-morbidity index in rheumatoid arthritis: time to think

(2015) Yasser El Miedany   CLINICAL RHEUMATOLOGY

Altered profile of circulating microparticles in rheumatoid arthritis patients

(2015) Javier Rodríguez-Carrio et al.   CLINICAL SCIENCE

Association between polymorphisms of interleukin 12 and rheumatoid arthritis associated biomarkers in a Chinese population

(2015) Li Shen et al.   CYTOKINE

Super-resolved calibration-free flow cytometric characterization of platelets and cell-derived microparticles in platelet-rich plasma

(2015) Anastasiya I. Konokhova et al.   CYTOMETRY PART A

Interleukin 17 inhibits progenitor cells in rheumatoid arthritis cartilage

(2015) Boris Schminke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential expression of COX-2 in osteoarthritis and rheumatoid arthritis

(2015) H.W. Fan et al.   GENETICS AND MOLECULAR RESEARCH

Therapeutic potential of IL-15 in rheumatoid arthritis

(2015) Xiao-Ke Yang et al.   HUMAN IMMUNOLOGY

Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions

(2015) Dhavalkumar D. Patel et al.   IMMUNITY

Targeting bromodomain-containing protein 4 (BRD4) benefits rheumatoid arthritis

(2015) Qing-gang Zhang et al.   IMMUNOLOGY LETTERS

The simultaneous occurrence of both hypercoagulability and hypofibrinolysis in blood and serum during systemic inflammation, and the roles of iron and fibrin(ogen)

(2015) Douglas B. Kell et al.   Integrative Biology

On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death

(2015) Douglas B. Kell et al.   Integrative Biology

Rheumatoid arthritis: Biological therapy other than anti-TNF

(2015) Daniela Rossi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Personalized medicine in rheumatoid arthritis: is the glass half full or half empty?

(2015) T. W. J. Huizinga   JOURNAL OF INTERNAL MEDICINE

Possible Implication of Red Blood Cells in the Prothrombotic Risk in Early Rheumatoid Arthritis

(2015) M. DI FRANCO et al.   JOURNAL OF RHEUMATOLOGY

Back to the metal age: battle for metals at the host–pathogen interface during urinary tract infection

(2015) Sargurunathan Subashchandrabose et al.   Metallomics

Epidemiology research in rheumatology—progress and pitfalls

(2015) Deborah P. M. Symmons   Nature Reviews Rheumatology

Atherosclerosis in rheumatoid arthritis: is it all about inflammation?

(2015) Sarah Skeoch et al.   Nature Reviews Rheumatology

Cardiovascular comorbidity in rheumatic diseases

(2015) Michael T. Nurmohamed et al.   Nature Reviews Rheumatology

Cytokines in rheumatoid arthritis — shaping the immunological landscape

(2015) Iain B. McInnes et al.   Nature Reviews Rheumatology

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3

(2015) Adam Denes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The influence of behavioural and psychological factors on medication adherence over time in rheumatoid arthritis patients: a study in the biologics era

(2015) Catharine Morgan et al.   RHEUMATOLOGY

Immunoregulatory role of IL-35 in T cells of patients with rheumatoid arthritis

(2015) Souichiro Nakano et al.   RHEUMATOLOGY

Platelet and red blood cell interactions and their role in rheumatoid arthritis

(2015) Oore-ofe O. Olumuyiwa-Akeredolu et al.   RHEUMATOLOGY INTERNATIONAL

Persisters unmasked

(2015) D. W. Holden   SCIENCE

Interleukin-18, interleukin-12B and interferon-γ gene polymorphisms in Brazilian patients with rheumatoid arthritis: a pilot study

(2015) H. D. Angelo et al.   TISSUE ANTIGENS

Platelet microparticle: A sensitive physiological “fine tuning” balancing factor in health and disease

(2015) Hadi Alphonse Goubran et al.   TRANSFUSION AND APHERESIS SCIENCE

Antibodies to high-density lipoproteins are associated with inflammation and cardiovascular disease in rheumatoid arthritis patients

(2015) Javier Rodríguez-Carrio et al.   Translational Research

What would be the observable consequences if phospholipid bilayer diffusion of drugs into cells is negligible?

(2015) Douglas B. Kell   TRENDS IN PHARMACOLOGICAL SCIENCES

Measures of Arthritis Activity Associated With Patient-Reported Improvement in Rheumatoid Arthritis When Assessed Prospectively Versus Retrospectively

(2015) Michael M. Ward et al.   ARTHRITIS CARE & RESEARCH

Epidemiology and Treatment of New-Onset and Established Rheumatoid Arthritis in an Insured US Population

(2015) Martin M. Crane et al.   ARTHRITIS CARE & RESEARCH

Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?

(2015) Ae R Noort et al.   ARTHRITIS RESEARCH & THERAPY

CD8+ T Cell Profiles in Patients With Rheumatoid Arthritis and Their Relationship to Disease Activity

(2015) Helena Carvalheiro et al.   Arthritis & Rheumatology

Review: Microbiome in Inflammatory Arthritis and Human Rheumatic Diseases

(2015) Jose U. Scher et al.   Arthritis & Rheumatology

The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis

(2015) Ceri A. Roberts et al.   Frontiers in Immunology

Viable Bacteria Associated with Red Blood Cells and Plasma in Freshly Drawn Blood Donations

(2015) Christian Damgaard et al.   PLoS One

Impact of Amyloid β25-35 on Membrane Stability, Energy Metabolism, and Antioxidant Enzymes in Erythrocytes

(2014) Lyudmila A. Tikhonova et al.   American Journal of Alzheimers Disease and Other Dementias

Efficacy of conventional synthetic disease-modifying antirheumatic drugs, glucocorticoids and tofacitinib: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis

(2014) Cécile Gaujoux-Viala et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis

(2014) Jackie L Nam et al.   ANNALS OF THE RHEUMATIC DISEASES

Therapeutic targets for rheumatoid arthritis: Progress and promises

(2014) Abdullah Alghasham et al.   AUTOIMMUNITY

CLEC-2 expression is maintained on activated platelets and on platelet microparticles

(2014) E. Gitz et al.   BLOOD

The cyclooxygenase-2/thromboxane A2 pathway: a bridge from rheumatoid arthritis to lung cancer?

(2014) Qing-Chun Huang et al.   CANCER LETTERS

Human IAPP amyloidogenic properties and pancreatic β-cell death

(2014) Marta S. Fernández   CELL CALCIUM

Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling

(2014) Agnieszka Płóciennikowska et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

New treatments for inflammatory rheumatic disease

(2014) Carlo Selmi et al.   IMMUNOLOGIC RESEARCH

Inflammation and vitamin D: the infection connection

(2014) Meg Mangin et al.   INFLAMMATION RESEARCH

Diagnostic morphology: biophysical indicators for iron-driven inflammatory diseases

(2014) Etheresia Pretorius et al.   Integrative Biology

The role of prostaglandin E2 receptor signaling of dendritic cells in rheumatoid arthritis

(2014) Xiao-Yi Jia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cytokine-Modulating Strategies and Newer Cytokine Targets for Arthritis Therapy

(2014) Shivaprasad Venkatesha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interleukin-27 Mediates Inflammation During Chronic Disease

(2014) Christopher Wynick et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells

(2014) Douglas B. Kell et al.   Metallomics

Oxidative stress in rheumatoid arthritis patients: relationship to diseases activity

(2014) Mirjana Veselinovic et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Association of IL-18 promoter gene polymorphisms with rheumatoid arthritis: a meta-analysis

(2014) Li-Ping Cai et al.   MOLECULAR BIOLOGY REPORTS

IL-6 biology: implications for clinical targeting in rheumatic disease

(2014) Leonard H. Calabrese et al.   Nature Reviews Rheumatology

IL-6 Amplifies TLR Mediated Cytokine and Chemokine Production: Implications for the Pathogenesis of Rheumatic Inflammatory Diseases

(2014) Ivan Caiello et al.   PLoS One

Interleukin-17 in human inflammatory diseases

(2014) Arezoo Gowhari Shabgah et al.   Postepy Dermatologii i Alergologii

A brief overview of amyloids and Alzheimer's disease

(2014) Sian-Yang Ow et al.   PROTEIN SCIENCE

Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell targets

(2014) D. E. Furst et al.   RHEUMATOLOGY

Association of Single Nucleotide Polymorphisms in theIL27Gene with Rheumatoid Arthritis

(2014) A. Paradowska-Gorycka et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The battle for iron

(2014) A. E. Armitage et al.   SCIENCE

Association between Interleukin-6 Gene Polymorphisms and Rheumatoid Arthritis in Chinese Han Population: A Case-Control Study and A Meta-analysis

(2014) Feng Li et al.   Scientific Reports

How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion

(2014) Douglas B. Kell et al.   Frontiers in Pharmacology

EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis

(2013) Alexandra N Colebatch et al.   ANNALS OF THE RHEUMATIC DISEASES

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

(2013) Josef S Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Rheumatoid arthritis is caused by aProteusurinary tract infection

(2013) Alan Ebringer et al.   APMIS

Bacterial Persister Cell Formation and Dormancy

(2013) Thomas K. Wood et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cardiovascular risk in rheumatoid arthritis: How to lower the risk?

(2013) D.F. van Breukelen-van der Stoep et al.   ATHEROSCLEROSIS

Incidence and Risk Factors of Legionella pneumophila Pneumonia During Anti-Tumor Necrosis Factor Therapy

(2013) Fanny Lanternier et al.   CHEST

Interleukin-27 as a potential therapeutic target for rheumatoid arthritis: has the time come?

(2013) Fang Gong et al.   CLINICAL RHEUMATOLOGY

Antioxidant Status and Energy State of Erythrocytes in Alzheimer Dementia: Probing for Markers

(2013) Elena A. Kosenko et al.   CNS & Neurological Disorders-Drug Targets

Pathogenesis of Alzheimer Disease: Role of Oxidative Stress, Amyloid-β Peptides, Systemic Ammonia and Erythrocyte Energy Metabolism

(2013) Elena Kosenko et al.   CNS & Neurological Disorders-Drug Targets

Persisters and beyond: Mechanisms of phenotypic drug resistance and drug tolerance in bacteria

(2013) Jemila C. Kester et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The human microbiome and autoimmunity

(2013) Amy D. Proal et al.   CURRENT OPINION IN RHEUMATOLOGY

Potential clinical applications of chelating drugs in diseases targeting transferrin-bound iron and other metals

(2013) Christina N Kontoghiorghe et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it

(2013) Douglas B. Kell   FEBS Journal

Association of Interleukin-18 (-137G/C) Polymorphism with Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Meta-Analysis

(2013) Dan Wen et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Blood Microbiota Dysbiosis Is Associated with the Onset of Cardiovascular Events in a Large General Population: The D.E.S.I.R. Study

(2013) Jacques Amar et al.   PLoS One

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

Age-Related Defects in Erythrocyte 2,3-Diphosphoglycerate Metabolism in Dementia

(2013) Yury Kaminsky et al.   Aging and Disease

Patient's global assessment of disease activity and patient's assessment of general health for rheumatoid arthritis activity assessment: are they equivalent?

(2012) Nasim Ahmed Khan et al.   ANNALS OF THE RHEUMATIC DISEASES

The incidence of rheumatoid arthritis in the UK: comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register

(2012) Jennifer H Humphreys et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting Persisters for Tuberculosis Control

(2012) Ying Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Porphyromonas gingivalisand disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis

(2012) Ted R. Mikuls et al.   ARTHRITIS AND RHEUMATISM

Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis

(2012) Jose U. Scher et al.   ARTHRITIS AND RHEUMATISM

The cholesterol content of the erythrocyte membrane is an important determinant of phosphatidylserine exposure

(2012) Rob van Zwieten et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Scientific discovery as a combinatorial optimisation problem: How best to navigate the landscape of possible experiments?

(2012) Douglas B. Kell   BIOESSAYS

Biologics-induced autoimmune diseases

(2012) Roberto Perez-Alvarez et al.   CURRENT OPINION IN RHEUMATOLOGY

The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so

(2012) Douglas B. Kell et al.   DRUG DISCOVERY TODAY

Increased synovial expression of IL-27 by IL-17 in rheumatoid arthritis

(2012) Seung Hoon Baek et al.   INFLAMMATION RESEARCH

LPS induces IL-8 expression through TLR4, MyD88, NF-kappaB and MAPK pathways in human dental pulp stem cells

(2012) W. He et al.   INTERNATIONAL ENDODONTIC JOURNAL

Possible roles of IL-12-family cytokines in rheumatoid arthritis

(2012) Richard M. Pope et al.   Nature Reviews Rheumatology

Genetics and iron in the systems biology of Parkinson’s disease and some related disorders

(2012) Claudia Funke et al.   NEUROCHEMISTRY INTERNATIONAL

Structural features and cytotoxicity of amyloid oligomers: Implications in Alzheimer's disease and other diseases with amyloid deposits

(2012) Massimo Stefani   PROGRESS IN NEUROBIOLOGY

Periodontitis in established rheumatoid arthritis patients: a cross-sectional clinical, microbiological and serological study

(2012) Menke Smit et al.   ARTHRITIS RESEARCH & THERAPY

Increased levels of interleukin-27 in patients with rheumatoid arthritis

(2011) Hui Shen et al.   ARTHRITIS AND RHEUMATISM

Rheumatoid arthritis

(2011) Loreto Carmona et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Co-morbidities in established rheumatoid arthritis

(2011) Nicola J. Gullick et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Heterogeneous bacterial persisters and engineering approaches to eliminate them

(2011) Kyle R Allison et al.   CURRENT OPINION IN MICROBIOLOGY

Critical Determinants of Cardiovascular Risk in Rheumatoid Arthritis

(2011) R. J. Bisoendial et al.   CURRENT PHARMACEUTICAL DESIGN

IL-27-producing CD14+ cells infiltrate inflamed joints of rheumatoid arthritis and regulate inflammation and chemotactic migration

(2011) Shimei Tanida et al.   CYTOKINE

Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept

(2011) J. Amar et al.   DIABETOLOGIA

Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only

(2011) Douglas B. Kell et al.   DRUG DISCOVERY TODAY

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

(2011) Jacques Amar et al.   EMBO Molecular Medicine

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies

(2011) M. Fauvart et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Rheumatoid Arthritis Disease Severity Indices in Administrative Databases: A Systematic Review

(2011) E. VINET et al.   JOURNAL OF RHEUMATOLOGY

Developing a Construct to Evaluate Flares in Rheumatoid Arthritis: A Conceptual Report of the OMERACT RA Flare Definition Working Group

(2011) R. ALTEN et al.   JOURNAL OF RHEUMATOLOGY

A battle for iron: host sequestration and Staphylococcus aureus acquisition

(2011) Kathryn P. Haley et al.   MICROBES AND INFECTION

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Are bloodstream leukocytes Trojan Horses for the metastasis of Staphylococcus aureus?

(2011) Guy E. Thwaites et al.   NATURE REVIEWS MICROBIOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prevalence of Genetic Haemochromatosis and Iron Overload in Patients Attending Rheumatology and Joint Replacement Clinics

(2011) Sc Donnelly et al.   SCOTTISH MEDICAL JOURNAL

Minocycline and doxycycline therapy in community patients with rheumatoid arthritis: prescribing patterns, patient-level determinants of use, and patient-reported side effects

(2011) Christopher J Smith et al.   ARTHRITIS RESEARCH & THERAPY

IFN-gamma promotes fibroblast-like synoviocytes motility

(2010) T Karonitsch et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice

(2010) C. J. Wruck et al.   ANNALS OF THE RHEUMATIC DISEASES

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples

(2010) Douglas B. Kell   ARCHIVES OF TOXICOLOGY

Excessive interleukin-1 signaling determines the development of Th1 and Th17 responses in chronic inflammation

(2010) Leo A. B. Joosten   ARTHRITIS AND RHEUMATISM

The struggle for iron - a metal at the host-pathogen interface

(2010) Manfred Nairz et al.   CELLULAR MICROBIOLOGY

The environment, geo-epidemiology, and autoimmune disease: Rheumatoid arthritis

(2010) Gabriel J. Tobón et al.   JOURNAL OF AUTOIMMUNITY

Direct Inhibition of Human RANK+ Osteoclast Precursors Identifies a Homeostatic Function of IL-1 

(2010) B. Lee et al.   JOURNAL OF IMMUNOLOGY

Methotrexate Is Highly Potent Against Pyrimethamine-Resistant Plasmodium vivax

(2010) Mallika Imwong et al.   JOURNAL OF INFECTIOUS DISEASES

Prostaglandin E2, an Immunoactivator

(2010) Daiji Sakata et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Observational Studies of Infections in Rheumatoid Arthritis: A Metaanalysis of Tumor Necrosis Factor Antagonists

(2010) S. BERNATSKY et al.   JOURNAL OF RHEUMATOLOGY

Antibodies to Porphyromonas gingivalis Are Associated with Anticitrullinated Protein Antibodies in Patients with Rheumatoid Arthritis and Their Relatives

(2010) C. A. HITCHON et al.   JOURNAL OF RHEUMATOLOGY

Targeting cardiovascular risk in rheumatoid arthritis: a dual role for statins

(2010) Radjesh J. Bisoendial et al.   Nature Reviews Rheumatology

The epidemiology of urinary tract infection

(2010) Betsy Foxman   Nature Reviews Urology

Distinct bacterial colonization patterns of Escherichia coli subtypes associate with rheumatoid factor status in early inflammatory arthritis

(2010) M. M. Newkirk et al.   RHEUMATOLOGY

Mycoplasmal lipid-associated membrane proteins and Mycoplasma arthritidis mitogen recognition by serum antibodies from patients with rheumatoid arthritis

(2010) Hermínio M. da Rocha Sobrinho et al.   RHEUMATOLOGY INTERNATIONAL

Platelet function in rheumatoid arthritis: arthritic and cardiovascular implications

(2010) Armen Yuri Gasparyan et al.   RHEUMATOLOGY INTERNATIONAL

The Prothrombotic State in Rheumatoid Arthritis: An Additive Risk Factor for Adverse Cardiovascular Events

(2010) Radjesh Bisoendial et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

The role of Interleukin 6 in the pathophysiology of rheumatoid arthritis

(2010) Srinivasan Srirangan et al.   Therapeutic Advances in Musculoskeletal Disease

Role of lung iron in determining the bacterial and host struggle in cystic fibrosis

(2009) D. W. Reid et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Circulating microparticles remain associated with complement activation despite intensive anti-inflammatory therapy in early rheumatoid arthritis

(2009) I. C. van Eijk et al.   ANNALS OF THE RHEUMATIC DISEASES

Transforming growth factor  1 and laminin-111 cooperate in the induction of interleukin-16 expression in synovial fibroblasts from patients with rheumatoid arthritis

(2009) K Warstat et al.   ANNALS OF THE RHEUMATIC DISEASES

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: The three-year prospective french research axed on tolerance of biotherapies registry

(2009) F. Tubach et al.   ARTHRITIS AND RHEUMATISM

Cardiovascular risk in rheumatoid arthritis

(2009) Michael T. Nurmohamed   AUTOIMMUNITY REVIEWS

Autoimmune disease in the era of the metagenome

(2009) Amy D. Proal et al.   AUTOIMMUNITY REVIEWS

Rheumatoid arthritis, Proteus, anti-CCP antibodies and Karl Popper

(2009) Alan Ebringer et al.   AUTOIMMUNITY REVIEWS

Autoimmune diseases induced by biological agents

(2009) Manuel Ramos-Casals et al.   AUTOIMMUNITY REVIEWS

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

(2009) Douglas B Kell   BMC Medical Genomics

Iron in innate immunity: starve the invaders

(2009) Tomas Ganz   CURRENT OPINION IN IMMUNOLOGY

Status of oxidative stress in rheumatoid arthritis

(2009) Pallinti VASANTHI et al.   International Journal of Rheumatic Diseases

Elucidation of the Mechanism by Which Catecholamine Stress Hormones Liberate Iron from the Innate Immune Defense Proteins Transferrin and Lactoferrin

(2009) S. M. Sandrini et al.   JOURNAL OF BACTERIOLOGY

Detection of periodontal bacterial DNA in serum and synovial fluid in refractory rheumatoid arthritis patients

(2009) Rita E. Martinez-Martinez et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Developing a Standardized Definition for Disease "Flare" in Rheumatoid Arthritis (OMERACT 9 Special Interest Group)

(2009) C. O. BINGHAM et al.   JOURNAL OF RHEUMATOLOGY

Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer

(2009) L. A. J. O'Neill et al.   PHARMACOLOGICAL REVIEWS

Iron homoeostasis in rheumatic disease

(2009) J. F. Baker et al.   RHEUMATOLOGY

IL-23 in the Pathogenesis of Rheumatoid Arthritis

(2009) A. Paradowska-Gorycka et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Pulsatile Stimulation Determines Timing and Specificity of NF- B-Dependent Transcription

(2009) L. Ashall et al.   SCIENCE

Conciliating binding efficiency and polypharmacology

(2009) Jordi Mestres et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Increased levels of circulating microparticles in primary Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity

(2009) Jérémie Sellam et al.   ARTHRITIS RESEARCH & THERAPY

The role of Toll-like receptors in rheumatoid arthritis

(2009) Qi-Quan Huang et al.   Current Rheumatology Reports

Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production

(2008) Shahla Abdollahi-Roodsaz et al.   ARTHRITIS AND RHEUMATISM

Autoimmune diseases induced by TNF-targeted therapies

(2008) Manuel Ramos-Casals et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

(2008) L. Verstrepen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

IL-17 induces the production of IL-16 in rheumatoid arthritis

(2008) Mi-La Cho et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis

(2008) Ted R. Mikuls et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inflammatory and prothrombotic biomarkers in patients with rheumatoid arthritis: Effects of tumor necrosis factor-α blockade

(2008) Francesca Ingegnoli et al.   JOURNAL OF AUTOIMMUNITY

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

(2008) Paul D. Dobson et al.   NATURE REVIEWS DRUG DISCOVERY

Microbial endocrinology: how stress influences susceptibility to infection

(2008) Primrose P.E. Freestone et al.   TRENDS IN MICROBIOLOGY