Therapeutic targets for rheumatoid arthritis: Progress and promises
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Title
Therapeutic targets for rheumatoid arthritis: Progress and promises
Authors
Keywords
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Journal
AUTOIMMUNITY
Volume 47, Issue 2, Pages 77-94
Publisher
Informa UK Limited
Online
2014-01-20
DOI
10.3109/08916934.2013.873413
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Note: Only part of the references are listed.- IL-17/Th17 mediated synovial inflammation is IL-22 independent
- (2013) Jan Piet van Hamburg et al. ANNALS OF THE RHEUMATIC DISEASES
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- (2013) Wang-Dong Xu et al. CLINICAL IMMUNOLOGY
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- (2013) Verica Paunovic et al. DRUGS
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- (2013) Eduardo Anitua et al. EXPERT OPINION ON BIOLOGICAL THERAPY
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- The Novel Role of IL-7 Ligation to IL-7 Receptor in Myeloid Cells of Rheumatoid Arthritis and Collagen-Induced Arthritis
- (2013) Z. Chen et al. JOURNAL OF IMMUNOLOGY
- Biologic agents in osteoarthritis: hopes and disappointments
- (2013) Xavier Chevalier et al. Nature Reviews Rheumatology
- The problem of choice: current biologic agents and future prospects in RA
- (2013) Ernest H. Choy et al. Nature Reviews Rheumatology
- Visfatin and adiponectin as novel markers for evaluation of metabolic disturbance in recently diagnosed rheumatoid arthritis patients
- (2013) Sahar Hossam El-Hini et al. RHEUMATOLOGY INTERNATIONAL
- Resistin in inflammatory and degenerative rheumatologic diseases
- (2013) S.M.H. Fadda et al. ZEITSCHRIFT FUR RHEUMATOLOGIE
- Progression to rheumatoid arthritis in early inflammatory arthritis is associated with low IL-7 serum levels
- (2012) Vincent Goëb et al. ANNALS OF THE RHEUMATIC DISEASES
- Adiponectin isoforms: a potential therapeutic target in rheumatoid arthritis?
- (2012) Klaus W Frommer et al. ANNALS OF THE RHEUMATIC DISEASES
- Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis
- (2012) Qi-Quan Huang et al. ARTHRITIS AND RHEUMATISM
- Regulation of inflammatory responses in tumor necrosis factor-activated and rheumatoid arthritis synovial macrophages by JAK inhibitors
- (2012) Anna Yarilina et al. ARTHRITIS AND RHEUMATISM
- B effector cells in rheumatoid arthritis and experimental arthritis
- (2012) Alison Finnegan et al. AUTOIMMUNITY
- B cells as effectors and regulators of autoimmunity
- (2012) Eliana Mariño et al. AUTOIMMUNITY
- Natural autoantibodies and associated B cells in immunity and autoimmunity
- (2012) Kaiissar Mannoor et al. AUTOIMMUNITY
- S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis
- (2012) T. Arumugam et al. CLINICAL CANCER RESEARCH
- Interleukin-7: a key Mediator in T Cell-driven Autoimmunity, Inflammation, and Tissue Destruction
- (2012) Angela Bikker et al. CURRENT PHARMACEUTICAL DESIGN
- Interleukin-32: A predominantly intracellular proinflammatory mediator that controls cell activation and cell death
- (2012) Bas Heinhuis et al. CYTOKINE
- Adiponectin: A biomarker for rheumatoid arthritis?
- (2012) Xiuping Chen et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Emerging role of interleukin-22 in autoimmune diseases
- (2012) Hai-Feng Pan et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Are biological targets the final goal for rheumatoid arthritis therapy?
- (2012) Puja Sharma et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Interleukin 22, a Potential Therapeutic Target for Rheumatoid Arthritis
- (2012) Q. XIE et al. JOURNAL OF RHEUMATOLOGY
- Increased Serum Interleukin 22 in Patients with Rheumatoid Arthritis and Correlation with Disease Activity
- (2012) LAURINDO FERREIRA da ROCHA et al. JOURNAL OF RHEUMATOLOGY
- Increased Frequencies of Th22 Cells as well as Th17 Cells in the Peripheral Blood of Patients with Ankylosing Spondylitis and Rheumatoid Arthritis
- (2012) Lei Zhang et al. PLoS One
- Adiponectin and Leptin Induce VCAM-1 Expression in Human and Murine Chondrocytes
- (2012) Javier Conde et al. PLoS One
- Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines
- (2012) N. J. Logsdon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The efficacy of biologic agents in patients with rheumatoid arthritis and an inadequate response to tumour necrosis factor inhibitors: a systematic review
- (2012) R. J. Moots et al. RHEUMATOLOGY
- Immunity 12 years after alemtuzumab in RA: CD5+ B-cell depletion, thymus-dependent T-cell reconstitution and normal vaccine responses
- (2012) A. E. Anderson et al. RHEUMATOLOGY
- Optimizing outcomes in patients with rheumatoid arthritis and an inadequate response to anti-TNF treatment
- (2012) P. Emery RHEUMATOLOGY
- IL-32 aggravates synovial inflammation and bone destruction and increases synovial natural killer cells in experimental arthritis models
- (2012) Young-Eun Park et al. RHEUMATOLOGY INTERNATIONAL
- Interleukin-32-induced thymic stromal lymphopoietin plays a critical role in macrophage differentiation through the activation of caspase-1 in vitro
- (2012) Hyun-Ja Jeong et al. ARTHRITIS RESEARCH & THERAPY
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- (2012) Lieying Fan et al. ARTHRITIS RESEARCH & THERAPY
- A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation.
- (2012) Asako Chiba et al. ARTHRITIS RESEARCH & THERAPY
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- (2012) Anupam Mitra et al. ARTHRITIS RESEARCH & THERAPY
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- (2012) Young-Mee Moon et al. ARTHRITIS RESEARCH & THERAPY
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- (2012) Vasileios Kyttaris Drug Design Development and Therapy
- Interleukin-7 levels in synovial fluid increase with age and MMP-1 levels decrease with progression of osteoarthritis
- (2011) René Rübenhagen et al. Acta Orthopaedica
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- (2011) Laszlo Otvos et al. PEPTIDES
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- (2011) Geert van Loo et al. ARTHRITIS RESEARCH & THERAPY
- Serum Adiponectin and Vaspin Levels in Rheumatoid Arthritis
- (2010) Metin Ozgen et al. ARCHIVES OF MEDICAL RESEARCH
- Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: Results of a randomized, double-blind, placebo-controlled, phase I/II study
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- Rheumatoid arthritis therapy: Advances from bench to bedside
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- Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis
- (2010) Cheng-Chi Chao et al. AUTOIMMUNITY
- KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase
- (2010) Antonio Garrido Montalban et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- IL-19, IL-20 and IL-24: potential therapeutic targets for autoimmune diseases
- (2010) Rui-Xue Leng et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Isolation and characterization of human interleukin-10–secreting T cells from peripheral blood
- (2010) Graziella Mazza et al. HUMAN IMMUNOLOGY
- A Multitude of Kinases—Which are the Best Targets in Treating Rheumatoid Arthritis?
- (2010) Tamsin M. Lindstrom et al. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
- Synovial/Serum leptin ratio in rheumatoid arthritis: the association with activity and erosion
- (2010) Shereen M. Olama et al. RHEUMATOLOGY INTERNATIONAL
- Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
- (2010) W. Hueber et al. Science Translational Medicine
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- (2009) Nemanja Damjanov et al. ARTHRITIS AND RHEUMATISM
- Serum adipokine levels in patients with systemic lupus erythematosus
- (2009) Juan B. De Sanctis et al. AUTOIMMUNITY
- AGE and their receptor RAGE in systemic autoimmune diseases: An inflammation propagating factor contributing to accelerated atherosclerosis
- (2009) Hans L. A. Nienhuis et al. AUTOIMMUNITY
- Prospective new biological therapies for rheumatoid arthritis
- (2009) Ladislav Šenolt et al. AUTOIMMUNITY REVIEWS
- The receptor RAGE: Bridging inflammation and cancer
- (2009) Astrid Riehl et al. Cell Communication and Signaling
- Soluble Forms of RAGE in Human Diseases: Clinical and Therapeutical Implications
- (2009) Francesca Santilli et al. CURRENT MEDICINAL CHEMISTRY
- ERK-Dependent T Cell Receptor Threshold Calibration in Rheumatoid Arthritis
- (2009) K. Singh et al. JOURNAL OF IMMUNOLOGY
- Periodic, Partial Inhibition of I B Kinase -Mediated Signaling Yields Therapeutic Benefit in Preclinical Models of Rheumatoid Arthritis
- (2009) K. M. Gillooly et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A Novel, Highly Selective, Tight Binding I B Kinase-2 (IKK-2) Inhibitor: A Tool to Correlate IKK-2 Activity to the Fate and Functions of the Components of the Nuclear Factor- B Pathway in Arthritis-Relevant Cells and Animal Models
- (2009) G. Mbalaviele et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Adiponectin and leptin serum concentrations in patients with rheumatoid arthritis
- (2009) Bożena Targońska-Stępniak et al. RHEUMATOLOGY INTERNATIONAL
- Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocytes
- (2009) Zafar Rasheed et al. ARTHRITIS RESEARCH & THERAPY
- Reduction of serum interleukin 7 levels upon methotrexate therapy in early rheumatoid arthritis correlates with disease suppression
- (2008) J A G van Roon et al. ANNALS OF THE RHEUMATIC DISEASES
- Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study
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- Role of the NF-κB axis in immune modulation of osteoclasts and bone loss
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- Review: Immune cells and mediators of inflammatory arthritis
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- LILRA5 is expressed by synovial tissue macrophages in rheumatoid arthritis, selectively induces pro-inflammatory cytokines and IL-10 and is regulated by TNF-α, IL-10 and IFN-γ
- (2008) Ainslie Mitchell et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Interleukin-7 in rheumatoid arthritis
- (2008) S. M. Churchman et al. RHEUMATOLOGY
- Expression of IL-19 and its receptors in RA: potential role for synovial hyperplasia formation
- (2008) N. Sakurai et al. RHEUMATOLOGY
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