Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?
Authors
Keywords
Rheumatoid Arthritis, Rheumatoid Arthritis Patient, Belimumab, Rheumatoid Arthritis Synovial Tissue, Smac Mimetic Compound
Journal
ARTHRITIS RESEARCH & THERAPY
Volume 17, Issue 1, Pages 15
Publisher
Springer Nature
Online
2015-01-27
DOI
10.1186/s13075-015-0527-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Negative feedback regulation of NF-κB-inducing kinase is proteasome-dependent but does not require cellular inhibitors of apoptosis
- (2014) Carolyn M. Gray et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia
- (2014) Po Y. Mak et al. BRITISH JOURNAL OF HAEMATOLOGY
- NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB
- (2014) Hengwei Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Lymphotoxin- 1 2 and LIGHT Induce Classical and Noncanonical NF- B-Dependent Proinflammatory Gene Expression in Vascular Endothelial Cells
- (2014) L. A. Madge et al. JOURNAL OF IMMUNOLOGY
- Dendritic Cells Require the NF- B2 Pathway for Cross-Presentation of Soluble Antigens
- (2014) E. F. Lind et al. JOURNAL OF IMMUNOLOGY
- Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies
- (2014) Stephen M. Condon et al. JOURNAL OF MEDICINAL CHEMISTRY
- NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis
- (2014) Ae R Noort et al. JOURNAL OF PATHOLOGY
- Noncanonical NF- B Signaling Is Limited by Classical NF- B Activity
- (2014) C. M. Gray et al. Science Signaling
- Inhibiting NF-κB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure–activity relationship, and co-crystal structures
- (2013) Kexue Li et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Endothelial cell–specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation
- (2013) Lucas Onder et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Efficacy and Safety of Belimumab in Patients with Rheumatoid Arthritis: A Phase II, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study
- (2013) W. Stohl et al. JOURNAL OF RHEUMATOLOGY
- NF- B inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF- B in immune-mediated diseases
- (2013) B. Sehnert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Th17 Cells
- (2012) Mohan S. Maddur et al. AMERICAN JOURNAL OF PATHOLOGY
- Tabalumab, an anti-BAFF monoclonal antibody, in patients with active rheumatoid arthritis with an inadequate response to TNF inhibitors
- (2012) Mark C Genovese et al. ANNALS OF THE RHEUMATIC DISEASES
- NF-κB2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors
- (2012) Brian A McCarthy et al. BMC CANCER
- Doxorubicin-induced activation of NF-κB in melanoma cells is abrogated by inhibition of IKKβ, but not by a novel IKKα inhibitor
- (2012) Nadin Pletz et al. EXPERIMENTAL DERMATOLOGY
- NF-κB function in B lymphocytes
- (2012) Mary Kaileh et al. IMMUNOLOGICAL REVIEWS
- The noncanonical NF-κB pathway
- (2012) Shao-Cong Sun IMMUNOLOGICAL REVIEWS
- The IKK -Dependent NF- B p52/RelB Noncanonical Pathway Is Essential To Sustain a CXCL12 Autocrine Loop in Cells Migrating in Response to HMGB1
- (2012) R. R. Kew et al. JOURNAL OF IMMUNOLOGY
- Safety, pharmacokinetics, and biologic activity of pateclizumab, a novel monoclonal antibody targeting lymphotoxin α: results of a phase I randomized, placebo-controlled trial
- (2012) Brinda Emu et al. ARTHRITIS RESEARCH & THERAPY
- Response to rituximab in patients with rheumatoid arthritis in different compartments of the immune system
- (2011) Maria J. H. Boumans et al. ARTHRITIS AND RHEUMATISM
- Current and novel therapeutics in the treatment of systemic lupus erythematosus
- (2011) Cagri Yildirim-Toruner et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Transcriptional regulation of the Th17 immune response by IKKα
- (2011) Li Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses
- (2011) Janin Hofmann et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inflammation meets cancer, with NF-κB as the matchmaker
- (2011) Yinon Ben-Neriah et al. NATURE IMMUNOLOGY
- The Pathogenesis of Rheumatoid Arthritis
- (2011) Iain B. McInnes et al. NEW ENGLAND JOURNAL OF MEDICINE
- Noncanonical NF- B regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development
- (2011) H. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Receptor activator of nuclear factor kappa B ligand serum and synovial fluid level. A comparative study between rheumatoid arthritis and osteoarthritis
- (2011) Abdou S. Ellabban et al. RHEUMATOLOGY INTERNATIONAL
- Angiogenesis and vasculogenesis in rheumatoid arthritis
- (2010) Zoltán Szekanecz et al. CURRENT OPINION IN RHEUMATOLOGY
- MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation
- (2010) Tao Li et al. NATURE IMMUNOLOGY
- NIK Stabilization in Osteoclasts Results in Osteoporosis and Enhanced Inflammatory Osteolysis
- (2010) Chang Yang et al. PLoS One
- Regulation and Function of NF-κB Transcription Factors in the Immune System
- (2009) Sivakumar Vallabhapurapu et al. Annual Review of Immunology
- The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases
- (2009) John A. Hamilton et al. ARTHRITIS AND RHEUMATISM
- Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
- (2009) Beatrix Bartok et al. IMMUNOLOGICAL REVIEWS
- Synovial Tissue Sublining CD68 Expression Is a Biomarker of Therapeutic Response in Rheumatoid Arthritis Clinical Trials: Consistency Across Centers
- (2009) B. BRESNIHAN et al. JOURNAL OF RHEUMATOLOGY
- Roles of the NF- B Pathway in Lymphocyte Development and Function
- (2009) S. Gerondakis et al. Cold Spring Harbor Perspectives in Biology
- Rheumatoid Arthritis Synovium Contains Two Subsets of CD83−DC-LAMP− Dendritic Cells with Distinct Cytokine Profiles
- (2008) M. Cristina Lebre et al. AMERICAN JOURNAL OF PATHOLOGY
- Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial
- (2008) Stanley B. Cohen et al. ARTHRITIS AND RHEUMATISM
- Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NF B-inducing kinase in stromal cells
- (2008) J. Kunisawa et al. BLOOD
- Anergic cells generated by blocking CD28 and CD40 costimulatory pathways in vitro ameliorate collagen induced arthritis
- (2008) Ling Li et al. CELLULAR IMMUNOLOGY
- TRAF2 and TRAF3 Signal Adapters Act Cooperatively to Control the Maturation and Survival Signals Delivered to B Cells by the BAFF Receptor
- (2008) Sandra Gardam et al. IMMUNITY
- RelB is the NF- B subunit downstream of NIK responsible for osteoclast differentiation
- (2008) S. Vaira et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T cells in rheumatoid arthritis
- (2008) Andrew P Cope ARTHRITIS RESEARCH & THERAPY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search