Persisters and beyond: Mechanisms of phenotypic drug resistance and drug tolerance in bacteria

Effects of Biofilm Growth on Plasmid Copy Number and Expression of Antibiotic Resistance Genes in Enterococcus faecalis

(2013) L. C. Cook et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Reduced Drug Uptake in Phenotypically Resistant Nutrient-Starved Nonreplicating Mycobacterium tuberculosis

(2013) Jansy Sarathy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Arrested Protein Synthesis Increases Persister-Like Cell Formation

(2013) Brian W. Kwan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Involvement of Efflux Pumps in the Resistance to Peptidoglycan Synthesis Inhibitors in Mycobacterium tuberculosis

(2013) Neela Dinesh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin Activity

(2013) Etienne Maisonneuve et al.   CELL

Identification and characterization of a highly motile and antibiotic refractory subpopulation involved in the expansion of swarming colonies ofPaenibacillus vortex

(2013) Dalit Roth et al.   ENVIRONMENTAL MICROBIOLOGY

Characterization of the MSMEG_2631 Gene (mmp) Encoding a Multidrug and Toxic Compound Extrusion (MATE) Family Protein in Mycobacterium smegmatis and Exploration of Its Polyspecific Nature Using Biolog Phenotype MicroArray

(2013) M. N. Mishra et al.   JOURNAL OF BACTERIOLOGY

The MerR-Like Regulator BrlR Confers Biofilm Tolerance by Activating Multidrug Efflux Pumps in Pseudomonas aeruginosa Biofilms

(2013) J. Liao et al.   JOURNAL OF BACTERIOLOGY

Biofilm infections, their resilience to therapy and innovative treatment strategies

(2013) U. Römling et al.   JOURNAL OF INTERNAL MEDICINE

Molecular Mechanism of Bacterial Persistence by HipA

(2013) Elsa Germain et al.   MOLECULAR CELL

Hsp90 Regulates Nongenetic Variation in Response to Environmental Stress

(2013) Yu-Ying Hsieh et al.   MOLECULAR CELL

Asymmetric growth and division inMycobacteriumspp.: compensatory mechanisms for non-medial septa

(2013) Bhupender Singh et al.   MOLECULAR MICROBIOLOGY

A problem of persistence: still more questions than answers?

(2013) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

Fe-S Cluster Biosynthesis Controls Uptake of Aminoglycosides in a ROS-Less Death Pathway

(2013) B. Ezraty et al.   SCIENCE

Dynamic Persistence of Antibiotic-Stressed Mycobacteria

(2013) Y. Wakamoto et al.   SCIENCE

Microanatomy at Cellular Resolution and Spatial Order of Physiological Differentiation in a Bacterial Biofilm

(2013) D. O. Serra et al.   mBio

Pharmacodynamics, Population Dynamics, and the Evolution of Persistence in Staphylococcus aureus

(2013) Paul J. T. Johnson et al.   PLoS Genetics

The Extracellular Matrix Component Psl Provides Fast-Acting Antibiotic Defense in Pseudomonas aeruginosa Biofilms

(2013) Nicole Billings et al.   PLoS Pathogens

Efflux Pumps of Mycobacterium tuberculosis Play a Significant Role in Antituberculosis Activity of Potential Drug Candidates

(2012) Meenakshi Balganesh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Relative Contributions of Physical Structure and Cell Density to the Antibiotic Susceptibility of Bacteria in Biofilms

(2012) Amy E. Kirby et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Role of Oxidative Stress in Persister Tolerance

(2012) Yanxia Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nutrient-Dependent Structural Changes in S. aureus Peptidoglycan Revealed by Solid-State NMR Spectroscopy

(2012) Xiaoxue Zhou et al.   BIOCHEMISTRY

The Expression of ABC Efflux Pump, Rv1217c–Rv1218c, and Its Association with Multidrug Resistance of Mycobacterium tuberculosis in China

(2012) Ke Wang et al.   CURRENT MICROBIOLOGY

Cell Division Site Placement and Asymmetric Growth in Mycobacteria

(2012) Graham Joyce et al.   PLoS One

Large mutational target size for rapid emergence of bacterial persistence

(2012) H. S. Girgis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artificial activation of toxin–antitoxin systems as an antibacterial strategy

(2012) Julia J. Williams et al.   TRENDS IN MICROBIOLOGY

Bet Hedging in Yeast by Heterogeneous, Age-Correlated Expression of a Stress Protectant

(2012) Sasha F. Levy et al.   PLOS BIOLOGY

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

(2011) Kristin N. Adams et al.   CELL

Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex

(2011) Liliana Rodrigues et al.   INFECTION GENETICS AND EVOLUTION

Competence-Dependent Endogenous DNA Rearrangement and Uptake of Extracellular DNA Give a Natural Variant of Streptococcus mutans without Biofilm Formation

(2011) N. Narisawa et al.   JOURNAL OF BACTERIOLOGY

Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies

(2011) M. Fauvart et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

(2011) B. B. Aldridge et al.   SCIENCE

Characterization and Transcriptome Analysis of Mycobacterium tuberculosis Persisters

(2011) I. Keren et al.   mBio

Metabolic Regulation of Mycobacterial Growth and Antibiotic Sensitivity

(2011) Seung-Hun Baek et al.   PLOS BIOLOGY

Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis

(2010) C. Sala et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Membrane Efflux and Influx Modulate both Multidrug Resistance and Virulence of Klebsiella pneumoniae in a Caenorhabditis elegans Model

(2010) S. Bialek et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of clonal strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients in Ontario, Canada

(2010) Trevor Beaudoin et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis

(2010) Michael A. Kohanski et al.   MOLECULAR CELL

Carbon flux rerouting during Mycobacterium tuberculosis growth arrest

(2010) Lanbo Shi et al.   MOLECULAR MICROBIOLOGY

Bacterial charity work leads to population-wide resistance

(2010) Henry H. Lee et al.   NATURE

Lethal protein produced in response to competition between sibling bacterial colonies

(2010) A. Be'er et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deadly competition between sibling bacterial colonies

(2009) A. Be'er et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic inheritance based evolution of antibiotic resistance in bacteria

(2008) Mike Adam et al.   BMC EVOLUTIONARY BIOLOGY

Swarming motility: a multicellular behaviour conferring antimicrobial resistance

(2008) Sandra Lai et al.   ENVIRONMENTAL MICROBIOLOGY

DegU and Spo0A Jointly Control Transcription of Two Loci Required for Complex Colony Development by Bacillus subtilis

(2008) D. T. Verhamme et al.   JOURNAL OF BACTERIOLOGY

Diarylquinolines Are Bactericidal for Dormant Mycobacteria as a Result of Disturbed ATP Homeostasis

(2008) Anil Koul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bet-hedging and epigenetic inheritance in bacterial cell development

(2008) J.-W. Veening et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

(2008) S. P. S. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA