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Title
Thymoquinone, as a Novel Therapeutic Candidate of Cancers
Authors
Keywords
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Journal
Pharmaceuticals
Volume 14, Issue 4, Pages 369
Publisher
MDPI AG
Online
2021-04-19
DOI
10.3390/ph14040369
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Note: Only part of the references are listed.- Synthesis and characterization of folic acid-chitosan nanoparticles loaded with thymoquinone to target ovarian cancer cells
- (2020) İskender İnce et al. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
- Indirubin-3-monoxime and thymoquinone exhibit synergistic efficacy as therapeutic combination in in-vitro and in-vivo models of Lung cancer
- (2020) Ayed A. Dera et al. ARCHIVES OF PHARMACAL RESEARCH
- Delivery of thymoquinone through hyaluronic acid-decorated mixed Pluronic® nanoparticles to attenuate angiogenesis and metastasis of triple-negative breast cancer
- (2020) Saurav Bhattacharya et al. JOURNAL OF CONTROLLED RELEASE
- Thymoquinone potentiates miR-16 and miR-375 expressions in hepatocellular carcinoma
- (2020) Aya O. Bashir et al. LIFE SCIENCES
- Thymoquinone synergizes with arsenic and interferon alpha to target human T-cell leukemia/lymphoma
- (2020) Marwa Houssein et al. LIFE SCIENCES
- Niosomal Drug Delivery Systems for Ocular Disease—Recent Advances and Future Prospects
- (2020) Saliha Durak et al. Nanomaterials
- Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells
- (2020) Nabil A. Alhakamy et al. Pharmaceutics
- Isolation of thymoquinone from Nigella sativa L. and Thymus vulgaris L., and its anti-proliferative effect on HeLa cancer cell lines
- (2019) Ayesha Siddique Butt et al. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
- PTK2 promotes cancer stem cell traits in hepatocellular carcinoma by activating Wnt/β-catenin signaling
- (2019) Zhongyi Fan et al. CANCER LETTERS
- Systems Biology Approaches to Investigate Genetic and Epigenetic Molecular Progression Mechanisms for Identifying Gene Expression Signatures in Papillary Thyroid Cancer
- (2019) Shan-Ju Yeh et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Piperine Enhances the Antioxidant and Anti-Inflammatory Activities of Thymoquinone against Microcystin-LR-Induced Hepatotoxicity and Neurotoxicity in Mice
- (2019) Mohamed M. Abdel-Daim et al. Oxidative Medicine and Cellular Longevity
- Thymoquinone enhances the effect of Gamma Knife in B16-F10 melanoma through inhibition of p-STAT3
- (2019) Mustafa Aziz Hatiboglu et al. World Neurosurgery
- Epigenetic role of thymoquinone: impact on cellular mechanism and cancer therapeutics
- (2019) Md. Asaduzzaman Khan et al. DRUG DISCOVERY TODAY
- Thymoquinone upregulates TRAIL/TRAILR2 expression and attenuates hepatocellular carcinoma in vivo model
- (2019) Sahar A. Helmy et al. LIFE SCIENCES
- Thymoquinone enhances the anticancer activity of doxorubicin against adult T-cell leukemia in vitro and in vivo through ROS-dependent mechanisms
- (2019) Maamoun Fatfat et al. LIFE SCIENCES
- Thymoquinone (2-Isoprpyl-5-methyl-1, 4-benzoquinone) as a chemopreventive / anticancer agent: Chemistry and Biological effects
- (2019) Anas Ahmad et al. SAUDI PHARMACEUTICAL JOURNAL
- Docetaxel Combined with Thymoquinone Induces Apoptosis in Prostate Cancer Cells via Inhibition of the PI3K/AKT Signaling Pathway
- (2019) Santosh Kumar Singh et al. Cancers
- Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3
- (2019) Ji Eun Park et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Inhibitory effects on melanogenesis by thymoquinone are mediated through the β‑catenin pathway in B16F10 mouse melanoma cells
- (2019) Han Jeong et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection
- (2018) Nunzia D'Onofrio et al. ANTIOXIDANTS & REDOX SIGNALING
- Thymoquinone: A novel strategy to combat cancer: A review
- (2018) Muhammad Imran et al. BIOMEDICINE & PHARMACOTHERAPY
- The synthesis and evaluation of thymoquinone analogues as anti-ovarian cancer and antimalarial agents
- (2018) Okiemute Rosa Johnson-Ajinwo et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Effects of thymoquinone on liver miRNAs and oxidative stress in Ehrlich acid mouse solid tumor model
- (2018) I Meral et al. BIOTECHNIC & HISTOCHEMISTRY
- Thymoquinone inhibits cell proliferation, migration, and invasion by regulating the elongation factor 2 kinase (eEF-2K) signaling axis in triple-negative breast cancer
- (2018) Nashwa Kabil et al. BREAST CANCER RESEARCH AND TREATMENT
- Thymoquinone Attenuates Myocardial Ischemia/Reperfusion Injury Through Activation of SIRT1 Signaling
- (2018) Yunyang Lu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Insights into the Targeting Potential of Thymoquinone for Therapeutic Intervention Against Triple-negative Breast Cancer
- (2018) Md Abul Barkat et al. CURRENT DRUG TARGETS
- Thymoquinone-based nanotechnology for cancer therapy: promises and challenges
- (2018) Farah Ballout et al. DRUG DISCOVERY TODAY
- Thymoquinone alleviates the experimentally induced Alzheimer’s disease inflammation by modulation of TLRs signaling
- (2018) YS Abulfadl et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Advances in studies of tyrosine kinase inhibitors and their acquired resistance
- (2018) Qinlian Jiao et al. Molecular Cancer
- Thymoquinone Induces Apoptosis in B16-F10 Melanoma Cell Through Inhibition of p-STAT3 and Inhibits Tumor Growth in a Murine Intracerebral Melanoma Model
- (2018) Mustafa Aziz Hatiboglu et al. World Neurosurgery
- Cytotoxic Effect of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) on Liver Cancer Cell Integrated with Hepatitis B Genome, Hep3B
- (2018) Aminah Suhaila Haron et al. Evidence-based Complementary and Alternative Medicine
- Ultra-high-performance liquid chromatography-based identification and quantification of thymoquinone in Nigella sativa extract from different geographical regions
- (2018) Niyaz Ahmad et al. Pharmacognosy Magazine
- Cancer-associated fibroblasts contribute to oral cancer cells proliferation and metastasis via exosome-mediated paracrine miR-34a-5p
- (2018) Yao-yin Li et al. EBioMedicine
- Thymoquinone-induced antitumor and apoptosis in human lung adenocarcinoma cells
- (2018) Saeed Samarghandian et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Synthesis, Biological Evaluation and Docking Studies of Benzoxazoles Derived from Thymoquinone
- (2018) Una Glamočlija et al. MOLECULES
- Synthesis and Optimization of Chitosan Nanoparticles Loaded with L-Ascorbic Acid and Thymoquinone
- (2018) Nurhanisah Othman et al. Nanomaterials
- PPARγ agonist efatutazone and gefitinib synergistically inhibit the proliferation of EGFR-TKI-resistant lung adenocarcinoma cells via the PPARγ/PTEN/Akt pathway
- (2017) Jie Ni et al. EXPERIMENTAL CELL RESEARCH
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- (2017) Nashwa H Zaher et al. Future Medicinal Chemistry
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- (2017) Nehal M. Elsherbiny et al. LIFE SCIENCES
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- (2017) Hsi-Hsien Hsu et al. WORLD JOURNAL OF GASTROENTEROLOGY
- miR‑145‑5p inhibits epithelial‑mesenchymal transition via the JNK signaling pathway by targeting MAP3K1 in non‑small cell lung cancer cells
- (2017) Yongmei Chang et al. Oncology Letters
- Effect of thymoquinone on head and neck squamous cell carcinoma cells in vitro: Synergism with radiation
- (2017) Ulana Kotowski et al. Oncology Letters
- A novel EGFR-TKI inhibitor (cAMP-H3BO3 complex) combined with thermal therapy is a promising strategy to improve lung cancer treatment outcomes
- (2017) Yongpeng Tong et al. Oncotarget
- Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene
- (2017) Jingjing Ma et al. Oncotarget
- Thymoquinone, as an anticancer molecule: from basic research to clinical investigation
- (2017) Md. Asaduzzaman Khan et al. Oncotarget
- Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells
- (2017) Jiuxia Pang et al. Oncotarget
- MicroRNA-34a targets epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion
- (2017) Saber Imani et al. Oncotarget
- Thymoquinone ameliorates diabetic phenotype in Diet-Induced Obesity mice via activation of SIRT-1-dependent pathways
- (2017) Shpetim Karandrea et al. PLoS One
- Thymoquinone: An IRAK1 inhibitor with in vivo and in vitro anti-inflammatory activities
- (2017) Muhammad Jahangir Hossen et al. Scientific Reports
- Cytotoxicity of thymoquinone alone or in combination with cisplatin (CDDP) against oral squamous cell carcinoma in vitro
- (2017) Omar M. Alaufi et al. Scientific Reports
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Abstract 4123: Thymoquinone inhibits bone metastasis in a breast cancer mouse model by modulating CXCR4/CXCL12 signaling axis
- (2016) Muthu K. Shanmugam et al. CANCER RESEARCH
- Inhibition of NF-κB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38
- (2016) Ming-Cheng Chen et al. ENVIRONMENTAL TOXICOLOGY
- Tyrosine kinase inhibitor TKI-258 inhibits cell motility in oral squamous cell carcinoma in vitro
- (2016) Anna Cecília Dias Maciel Carneiro et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer
- (2016) Sabnam Parbin et al. Molecular BioSystems
- Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis
- (2016) Azza S. M. Awad et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Thymoquinone from Nigella sativa Seeds Promotes the Antitumor Activity of Noncytotoxic Doses of Topotecan in Human Colorectal Cancer Cells in Vitro
- (2016) Rana Khalife et al. PLANTA MEDICA
- Thymoquinone inhibits proliferation in gastric cancerviathe STAT3 pathwayin vivoandin vitro
- (2016) Wen-Qian Zhu et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Thymoquinone chemosensitizes colon cancer cells through inhibition of NF-κB
- (2016) Lida Zhang et al. Oncology Letters
- PEGylated-thymoquinone-nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a
- (2015) Saurav Bhattacharya et al. BIOMATERIALS
- Thymoquinone Induces Caspase-Independent, Autophagic Cell Death in CPT-11-Resistant LoVo Colon Cancer via Mitochondrial Dysfunction and Activation of JNK and p38
- (2015) Ming-Cheng Chen et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- SIRT1 regulates oncogenesis via a mutant p53-dependent pathway in hepatocellular carcinoma
- (2015) Zheng Yun Zhang et al. JOURNAL OF HEPATOLOGY
- Overcoming Akt Induced Therapeutic Resistance in Breast Cancer through siRNA and Thymoquinone Encapsulated Multilamellar Gold Niosomes
- (2015) Shashi Rajput et al. MOLECULAR PHARMACEUTICS
- Thymoquinone and its therapeutic potentials
- (2015) Sara Darakhshan et al. PHARMACOLOGICAL RESEARCH
- Black Cumin (Nigella sativa) and Its Active Constituent, Thymoquinone: An Overview on the Analgesic and Anti-inflammatory Effects
- (2015) Bahareh Amin et al. PLANTA MEDICA
- The combination of thymoquinone and paclitaxel shows anti-tumor activity through the interplay with apoptosis network in triple-negative breast cancer
- (2015) Çağrı Şakalar et al. TUMOR BIOLOGY
- Thymoquinone enhances cisplatin-response through direct tumor effects in a syngeneic mouse model of ovarian cancer
- (2015) Andrew J. Wilson et al. Journal of Ovarian Research
- Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition
- (2015) Md. Asaduzzaman Khan et al. Oncotarget
- Thymoquinone-Loaded Nanostructured Lipid Carrier Exhibited Cytotoxicity towards Breast Cancer Cell Lines (MDA-MB-231 and MCF-7) and Cervical Cancer Cell Lines (HeLa and SiHa)
- (2015) Wei Keat Ng et al. Biomed Research International
- Mechanism of Resistance and Novel Targets Mediating Resistance to EGFR and c-Met Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer
- (2015) Gregory M. Botting et al. PLoS One
- P53 and Sirt1: Routes of metabolism and genome stability
- (2014) Stefania Gonfloni et al. BIOCHEMICAL PHARMACOLOGY
- Novel combination of docetaxel and thymoquinone induces synergistic cytotoxicity and apoptosis in DU-145 human prostate cancer cells by modulating PI3K–AKT pathway
- (2014) A. Dirican et al. Clinical & Translational Oncology
- Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways
- (2014) Arshad H. Rahmani et al. Evidence-based Complementary and Alternative Medicine
- Nano-niosomes as nanoscale drug delivery systems: An illustrated review
- (2014) Saeid Moghassemi et al. JOURNAL OF CONTROLLED RELEASE
- Aqueous Solubility and Degradation Kinetics of the Phytochemical Anticancer Thymoquinone; Probing the Effects of Solvents, pH and Light
- (2014) Jumah Salmani et al. MOLECULES
- Thymoquinone inhibits proliferation and invasion of human nonsmall-cell lung cancer cells via ERK pathway
- (2014) Jing Yang et al. TUMOR BIOLOGY
- Liposome: classification, preparation, and applications
- (2013) Abolfazl Akbarzadeh et al. Nanoscale Research Letters
- Nanocarrier based formulation of Thymoquinone improves oral delivery: Stability assessment, in vitro and in vivo studies
- (2012) Anjali Singh et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Thymoquinone in liposomes: a study of loading efficiency and biological activity towards breast cancer
- (2012) Fadwa Odeh et al. DRUG DELIVERY
- Development and evaluation of thymoquinone-encapsulated chitosan nanoparticles for nose-to-brain targeting: a pharmacoscintigraphic study
- (2012) Sanjar Alam et al. International Journal of Nanomedicine
- Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents
- (2011) Rassoul Dinarvand et al. International Journal of Nanomedicine
- Synthesis and Characterization of PHV-Block-mPEG Diblock Copolymer and Its Formation of Amphiphilic Nanoparticles for Drug Delivery
- (2011) Mohsin Shah et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Endocytosis unplugged: multiple ways to enter the cell
- (2010) Sudha Kumari et al. CELL RESEARCH
- Delivery of phytochemical thymoquinone using molecular micelle modified poly(D, L lactide-co-glycolide) (PLGA) nanoparticles
- (2010) Gabriela M Ganea et al. NANOTECHNOLOGY
- Thymoquinone, a potential therapeutic agent of Nigella sativa, binds to site I of human serum albumin
- (2010) G. Lupidi et al. PHYTOMEDICINE
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- (2010) Mehmet Kanter TOXICOLOGY AND INDUSTRIAL HEALTH
- Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin
- (2009) Huanli Sun et al. BIOMATERIALS
- Thymoquinone supplementation induces quinone reductase and glutathione transferase in mice liver: possible role in protection against chemical carcinogenesis and toxicity
- (2009) Mahmoud N. Nagi et al. PHYTOTHERAPY RESEARCH
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