Cytotoxic Effect of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) on Liver Cancer Cell Integrated with Hepatitis B Genome, Hep3B

Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice

(2016) Yong Sze Ong et al.   International Journal of Nanomedicine

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

(2015) Edgar Pérez-Herrero et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis

(2014) Abdelkader E. Ashour et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mechanistic perspectives on cancer chemoprevention/chemotherapeutic effects of thymoquinone

(2014) Juthika Kundu et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells

(2013) Bipul R. Acharya et al.   BIOCHIMIE

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets

(2013) Juthika Kundu et al.   FOOD AND CHEMICAL TOXICOLOGY

Selective Induction of Tumor Cell Apoptosis by a Novel P450-mediated Reactive Oxygen Species (ROS) Inducer Methyl 3-(4-Nitrophenyl) Propiolate

(2013) Xiaoxiao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular carcinoma

(2013) Subramanian Raghunandhakumar et al.   TOXICOLOGY LETTERS

The Predicted Molecular Weight of Nrf2: It Is What It Is Not

(2012) Alexandria Lau et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Differential induction of apoptosis in human breast cancer cell lines by phenethyl isothiocyanate, a glutathione depleting agent

(2012) Sharifah S. Syed Alwi et al.   CELL STRESS & CHAPERONES

Quinone-Induced Activation of Keap1/Nrf2 Signaling by Aspirin Prodrugs Masquerading as Nitric Oxide

(2012) Tareisha Dunlap et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Pro-Oxidant Natural Products as Anticancer Agents

(2012) Carmen Martin-Cordero et al.   CURRENT DRUG TARGETS

Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growthin vivo

(2012) Samir Attoub et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein

(2011) Wei Keat Ng et al.   TOXICOLOGY IN VITRO

Stability-indicating ultra-performance liquid chromatography method for the estimation of thymoquinone and its application in biopharmaceutical studies

(2010) Shadab A. Pathan et al.   BIOMEDICAL CHROMATOGRAPHY

Nrf2–ARE signaling pathway and natural products for cancer chemoprevention

(2010) Cui Rong Zhao et al.   Cancer Epidemiology

Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: Physicochemical characterization and pharmacokinetics

(2010) Chih-Chieh Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Mechanisms of HBV-related hepatocarcinogenesis

(2010) Christine Neuveut et al.   JOURNAL OF HEPATOLOGY

Review on Molecular and Therapeutic Potential of Thymoquinone in Cancer

(2010) Sanjeev Banerjee et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Thymoquinone Attenuates Diethylnitrosamine Induction of Hepatic Carcinogenesis Through Antioxidant Signaling

(2010) Mohamed M. Sayed-Ahmed et al.   Oxidative Medicine and Cellular Longevity

Cancer Prevention With Natural Compounds

(2010) Norleena P. Gullett et al.   SEMINARS IN ONCOLOGY

Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1

(2009) Mahmoud Alhosin et al.   BIOCHEMICAL PHARMACOLOGY

Hepatitis B virus X gene is implicated in liver carcinogenesis

(2009) Katsuro Koike   CANCER LETTERS

Antitumor Activity of Gemcitabine and Oxaliplatin Is Augmented by Thymoquinone in Pancreatic Cancer

(2009) Sanjeev Banerjee et al.   CANCER RESEARCH

Caspase-7: A protease involved in apoptosis and inflammation

(2009) Mohamed Lamkanfi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGA1 Levels Influence Mitochondrial Function and Mitochondrial DNA Repair Efficiency

(2009) L. Mao et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Reactive oxygen species: A double-edged sword in oncogenesis

(2009) Jin-Shui Pan et al.   WORLD JOURNAL OF GASTROENTEROLOGY

In vitro toxicological properties of thymoquinone

(2008) M. Khader et al.   FOOD AND CHEMICAL TOXICOLOGY

Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways

(2008) T. Yi et al.   MOLECULAR CANCER THERAPEUTICS

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA