The combination of thymoquinone and paclitaxel shows anti-tumor activity through the interplay with apoptosis network in triple-negative breast cancer

Novel combination of docetaxel and thymoquinone induces synergistic cytotoxicity and apoptosis in DU-145 human prostate cancer cells by modulating PI3K–AKT pathway

(2014) A. Dirican et al.   Clinical & Translational Oncology

Thymoquinone alleviates thioacetamide-induced hepatic fibrosis and inflammation by activating LKB1–AMPK signaling pathway in mice

(2014) Ting Bai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Thymoquinone Restores Radiation-Induced TGF-β Expression and Abrogates EMT in Chemoradiotherapy of Breast Cancer Cells

(2014) Shashi Rajput et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis

(2014) Abdelkader E. Ashour et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Thymoquinone, A Bioactive Component of Black Caraway Seeds, Causes G1 Phase Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells with Mutant p53

(2014) Kimberly M. Sutton et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Molecular targeting of Akt by thymoquinone promotes G1 arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells

(2013) Shashi Rajput et al.   LIFE SCIENCES

Pronounced transcriptional regulation of apoptotic and TNF–NF-kappa-B signaling genes during the course of thymoquinone mediated apoptosis in HeLa cells

(2013) Cagri Sakalar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Anti-fibrotic effect of thymoquinone on hepatic stellate cells

(2013) Mohammed Ghazwani et al.   PHYTOMEDICINE

Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS

(2013) Chern Chiuh Woo et al.   PLoS One

Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growthin vivo

(2012) Samir Attoub et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells

(2012) G M A Ajabnoor et al.   Cell Death & Disease

Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis

(2011) Reelma Velho‑Pereira et al.   CELL BIOLOGY INTERNATIONAL

Thymoquinone Inhibits the CXCL12-Induced Chemotaxis of Multiple Myeloma Cells and Increases Their Susceptibility to Fas-Mediated Apoptosis

(2011) Gamal Badr et al.   PLoS One

RETRACTED: Thymoquinone poly (lactide-co-glycolide) nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, and chemosensitization potential

(2010) Jayaraj Ravindran et al.   BIOCHEMICAL PHARMACOLOGY

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

(2010) Feng Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Combinatorial effects of thymoquinone on the anti-cancer activity of doxorubicin

(2010) Katharina Effenberger-Neidnicht et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells

(2010) El-Shaimaa A. Arafa et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden

(2010) L Connelly et al.   ONCOGENE

Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells

(2010) Navdeep Chehl et al.   HPB

Antitumor Activity of Gemcitabine and Oxaliplatin Is Augmented by Thymoquinone in Pancreatic Cancer

(2009) Sanjeev Banerjee et al.   CANCER RESEARCH

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

GATA3 in development and cancer differentiation: Cells GATA have it!

(2009) Jonathan Chou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Methylation profiles of 22 candidate genes in breast cancer using high-throughput MALDI-TOF mass array

(2009) R Radpour et al.   ONCOGENE

Targeting Nuclear Factor- B Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis

(2008) G. Sethi et al.   MOLECULAR CANCER RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH