Therapeutic Implications of Black Seed and Its Constituent Thymoquinone in the Prevention of Cancer through Inactivation and Activation of Molecular Pathways

Prognostic Value of Tissue Vascular Endothelial Growth Factor Expression in Bladder Cancer: a Meta-analysis

(2013) Yu-Jing Huang et al.   Asian Pacific Journal of Cancer Prevention

Thymoquinone-induced reactive oxygen species causes apoptosis of chondrocytes via PI3K/Akt and p38kinase pathway

(2013) Seon-Mi Yu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Pronounced transcriptional regulation of apoptotic and TNF–NF-kappa-B signaling genes during the course of thymoquinone mediated apoptosis in HeLa cells

(2013) Cagri Sakalar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

In vivo modulation of iNOS pathway in hepatocellular carcinoma by Nigella sativa

(2013) Moustafa Fathy et al.   Environmental Health and Preventive Medicine

Thymoquinone (TQ) regulates cyclooxygenase-2 expression and prostaglandin E2 production through PI3kinase (PI3K)/p38 kinase pathway in human breast cancer cell line, MDA-MB-231

(2012) Seon Mi Yu et al.   Animal Cells and Systems

Polo-Box Domain Inhibitor Poloxin Activates the Spindle Assembly Checkpoint and Inhibits Tumor Growth in Vivo

(2011) Juping Yuan et al.   AMERICAN JOURNAL OF PATHOLOGY

Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway

(2011) Chern Chiuh Woo et al.   BIOCHEMICAL PHARMACOLOGY

Thymoquinone: Potential cure for inflammatory disorders and cancer

(2011) Chern Chiuh Woo et al.   BIOCHEMICAL PHARMACOLOGY

Signal transducers and activators of transcription—from cytokine signalling to cancer biology

(2011) Cristina Isabel Santos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation

(2011) Kamel Chaieb et al.   BMC Complementary and Alternative Medicine

Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma

(2011) Azhar R. Hussain et al.   FREE RADICAL BIOLOGY AND MEDICINE

Aberrant promoter methylation and inactivation of PTEN gene in cervical carcinoma from Indian population

(2011) M. Moshahid Alam Rizvi et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

PTEN-mediated AKT activation contributes to the reduced apoptosis among Indian oral squamous cell carcinoma patients

(2011) Nisreen Sherif Alyasiri et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-XL expression

(2011) Gamal Badr et al.   Lipids in Health and Disease

Allelic Loss of 10q23.3, the PTEN Gene Locus in Cervical Carcinoma from Northern Indian Population

(2011) M. Moshahid Alam Rizvi et al.   PATHOLOGY & ONCOLOGY RESEARCH

HPV typing and its relation with apoptosis in cervical carcinoma from Indian population

(2011) M. Shabbir Alam et al.   TUMOR BIOLOGY

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

(2010) Feng Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

COX-2 is overexpressed in primary prostate cancer with metastatic potential and may predict survival. A comparison study between COX-2, TGF-β, IL-10 and Ki67

(2010) Elin Richardsen et al.   Cancer Epidemiology

Terpene Conjugates of theNigella sativaSeed-Oil Constituent Thymoquinone with Enhanced Efficacy in Cancer Cells

(2010) Katharina Effenberger et al.   CHEMISTRY & BIODIVERSITY

Thymoquinone supplementation reverses acetaminophen-induced oxidative stress, nitric oxide production and energy decline in mice liver

(2010) Mahmoud N. Nagi et al.   FOOD AND CHEMICAL TOXICOLOGY

Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis

(2010) France Vaillancourt et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells

(2010) El-Shaimaa A. Arafa et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Review on Molecular and Therapeutic Potential of Thymoquinone in Cancer

(2010) Sanjeev Banerjee et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Structure-Activity Studies on Therapeutic Potential of Thymoquinone Analogs in Pancreatic Cancer

(2010) Sanjeev Banerjee et al.   PHARMACEUTICAL RESEARCH

Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells

(2010) Navdeep Chehl et al.   HPB

Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic β-cells of streptozotocin-induced diabetic rats

(2010) Nabila E. ABDELMEGUID et al.   Journal of Diabetes

Antitumor Activity of Gemcitabine and Oxaliplatin Is Augmented by Thymoquinone in Pancreatic Cancer

(2009) Sanjeev Banerjee et al.   CANCER RESEARCH

Repression of NHE1 Expression by PPAR  Activation Is a Potential New Approach for Specific Inhibition of the Growth of Tumor Cells In vitro and In vivo

(2009) A. P. Kumar et al.   CANCER RESEARCH

Effects of Thymoquinone-Fatty Acid Conjugates on Cancer Cells

(2009) Sandra Breyer et al.   ChemMedChem

Thymoquinone-induced suicidal erythrocyte death

(2009) Syed M. Qadri et al.   FOOD AND CHEMICAL TOXICOLOGY

Antimutagenic effects of ethanolic extracts from selected Palestinian medicinal plants

(2009) M. Khader et al.   JOURNAL OF ETHNOPHARMACOLOGY

Thymoquinone supplementation induces quinone reductase and glutathione transferase in mice liver: possible role in protection against chemical carcinogenesis and toxicity

(2009) Mahmoud N. Nagi et al.   PHYTOTHERAPY RESEARCH

Thymoquinone Ameliorates Renal Oxidative Damage and Proliferative Response Induced by Mercuric Chloride in Rats

(2008) Abdel-Motaal M. Fouda et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Vegetables and Fruits in Relation to Cancer Risk: Evidence from the Greek EPIC Cohort Study

(2008) V. Benetou et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Thymoquinone Triggers Inactivation of the Stress Response Pathway Sensor CHEK1 and Contributes to Apoptosis in Colorectal Cancer Cells

(2008) H. Gali-Muhtasib et al.   CANCER RESEARCH

In vitro toxicological properties of thymoquinone

(2008) M. Khader et al.   FOOD AND CHEMICAL TOXICOLOGY

Antihypertensive effect ofNigella sativaseed extract in patients with mild hypertension

(2008) Farshad Roghani Dehkordi et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

The role of herbs and spices in cancer prevention

(2008) Christine M. Kaefer et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Targeting Nuclear Factor- B Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis

(2008) G. Sethi et al.   MOLECULAR CANCER RESEARCH

Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways

(2008) T. Yi et al.   MOLECULAR CANCER THERAPEUTICS

Phenolic composition and biological activities of Tunisian Nigella sativa L. shoots and roots

(2007) Soumaya Bourgou et al.   COMPTES RENDUS BIOLOGIES