Synergistic Protection by Isoquercitrin and Quercetin against Glutamate-Induced Oxidative Cell Death in HT22 Cells via Activating Nrf2 and HO-1 Signaling Pathway: Neuroprotective Principles and Mechanisms of Dendropanax morbifera Leaves

Potential Implications of Quercetin and its Derivatives in Cardioprotection

(2020) Kristina Ferenczyova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nrf2 and Ferroptosis: A New Research Direction for Neurodegenerative Diseases

(2020) Xiaohua Song et al.   Frontiers in Neuroscience

Dendropanax Morbiferus and Other Species from the Genus Dendropanax: Therapeutic Potential of Its Traditional Uses, Phytochemistry, and Pharmacology

(2020) Rengasamy Balakrishnan et al.   Antioxidants

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

(2019) Antonio Cuadrado et al.   NATURE REVIEWS DRUG DISCOVERY

Critical Role of Nrf2 in Experimental Ischemic Stroke

(2019) Lei Liu et al.   Frontiers in Pharmacology

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

(2019) Natalia Robledinos-Antón et al.   Oxidative Medicine and Cellular Longevity

Ageing as a risk factor for neurodegenerative disease

(2019) Yujun Hou et al.   Nature Reviews Neurology

Neuroprotective effects of Dendropanax morbifera leaves on glutamate-induced oxidative cell death in HT22 mouse hippocampal neuronal cells

(2019) Hye-Jin Park et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuronal Cell Death

(2018) Michael Fricker et al.   PHYSIOLOGICAL REVIEWS

Mitochondrial Chaperones in the Brain: Safeguarding Brain Health and Metabolism?

(2018) José Pedro Castro et al.   Frontiers in Endocrinology

Astroglia as a cellular target for neuroprotection and treatment of neuro-psychiatric disorders

(2017) Beihui Liu et al.   GLIA

Nrf2, the Master Regulator of Anti-Oxidative Responses

(2017) Sandra Vomund et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Isoquercetin activates the ERK1/2-Nrf2 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitro

(2017) Miao Chen et al.   Experimental and Therapeutic Medicine

Chemical constituents from a Gynostemma laxum and their antioxidant and neuroprotective activities

(2017) Ji Yeon Seo et al.   Chinese Medicine

Anti-amnesic effect of Dendropanax morbifera via JNK signaling pathway on cognitive dysfunction in high-fat diet-induced diabetic mice

(2016) Jong Min Kim et al.   BEHAVIOURAL BRAIN RESEARCH

Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions

(2016) Natarajan Suganthy et al.   BIOMEDICINE & PHARMACOTHERAPY

Dendropanax morbifera Léveille extract ameliorates cadmium-induced impairment in memory and hippocampal neurogenesis in rats

(2016) Woosuk Kim et al.   BMC Complementary and Alternative Medicine

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Antioxidant effects of Dendropanax morbifera Léveille extract in the hippocampus of mercury-exposed rats

(2015) Woosuk Kim et al.   BMC Complementary and Alternative Medicine

Researching glutamate – induced cytotoxicity in different cell lines: a comparative/collective analysis/study

(2015) Aristeidis A. Kritis et al.   Frontiers in Cellular Neuroscience

Isolation and characterization of bioactive compounds from Lepisorus thunbergianus (Kaulf.)

(2015) Jinfeng Yang et al.   Arabian Journal of Chemistry

Calcium and ROS: A mutual interplay

(2015) Agnes Görlach et al.   Redox Biology

Dendropanax morbifera Léveille extract facilitates cadmium excretion and prevents oxidative damage in the hippocampus by increasing antioxidant levels in cadmium-exposed rats

(2014) Woosuk Kim et al.   BMC Complementary and Alternative Medicine

Pathophysiogenesis of Mesial Temporal Lobe Epilepsy: Is Prevention of Damage Antiepileptogenic?

(2014) G. Curia et al.   CURRENT MEDICINAL CHEMISTRY

Isoquercitrin: Pharmacology, toxicology, and metabolism

(2014) Kateřina Valentová et al.   FOOD AND CHEMICAL TOXICOLOGY

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

(2013) Hemant Kumar et al.   NATURAL PRODUCT REPORTS

Mitochondria impact brain function and cognition

(2013) M. Picard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Mitochondrial Regulation of Cell Death

(2013) S. W. G. Tait et al.   Cold Spring Harbor Perspectives in Biology

Flavonoid Bioavailability and Attempts for Bioavailability Enhancement

(2013) Surangi Thilakarathna et al.   Nutrients

Keap1 degradation by autophagy for the maintenance of redox homeostasis

(2012) K. Taguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders

(2011) Giovanni Scapagnini et al.   MOLECULAR NEUROBIOLOGY

Quercetin Protects Against Oxidative Stress Associated Damages in a Rat Model of Transient Focal Cerebral Ischemia and Reperfusion

(2011) Ajmal Ahmad et al.   NEUROCHEMICAL RESEARCH

Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice

(2011) Simone E. Thal et al.   NEUROSCIENCE LETTERS

Molecular and cellular mechanisms of excitotoxic neuronal death

(2010) Yan Wang et al.   APOPTOSIS

After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult

(2010) Florencia Arredondo et al.   FREE RADICAL BIOLOGY AND MEDICINE

p62, an autophagy hero or culprit?

(2010) Tor Erik Rusten et al.   NATURE CELL BIOLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

Activation of autophagy during glutamate-induced HT22 cell death

(2009) Hansoo Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells

(2009) Masayuki Fukui et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Mitochondrial membrane permeabilization in neuronal injury

(2009) Lorenzo Galluzzi et al.   NATURE REVIEWS NEUROSCIENCE

Studies of intestinal permeability of 36 flavonoids using Caco-2 cell monolayer model

(2008) Xiao-Juan Tian et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS