Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

The Major Green Tea Polyphenol, (-)-Epigallocatechin-3-Gallate, Induces Heme Oxygenase in Rat Neurons and Acts as an Effective Neuroprotective Agent against Oxidative Stress

(2013) Loriana Romeo et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

The Nrf2-ARE Pathway

(2010) Jeffrey A. Johnson et al.   Annals of the New York Academy of Sciences

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

Sulforaphane protects brains against hypoxic–ischemic injury through induction of Nrf2-dependent phase 2 enzyme

(2010) Zhang Ping et al.   BRAIN RESEARCH

The Flavanol (−)-Epicatechin Prevents Stroke Damage through the Nrf2/HO1 Pathway

(2010) Zahoor A Shah et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling

(2010) Christopher D. Morrison et al.   JOURNAL OF NEUROCHEMISTRY

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Different Susceptibility to the Parkinson's Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1

(2010) Nadia G. Innamorato et al.   PLoS One

Curcumin, inflammation, ageing and age-related diseases

(2010) E Sikora et al.   Immunity & Ageing

2009 Alzheimer's disease facts and figures

(2009)   Alzheimers & Dementia

Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans?

(2009) Pamela Boon Li Pun et al.   BIOGERONTOLOGY

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia

(2009) Chenhui Yang et al.   BRAIN RESEARCH

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease

(2009) Ana I. Rojo et al.   GLIA

Six-Month Randomized, Placebo-Controlled, Double-Blind, Pilot Clinical Trial of Curcumin in Patients With Alzheimer Disease

(2009) Larry Baum et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer’s disease

(2009) Magali Dumont et al.   JOURNAL OF NEUROCHEMISTRY

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

(2009) Tae Gen Son et al.   JOURNAL OF NEUROCHEMISTRY

Naturally occurring phytochemicals for the prevention of Alzheimer’s disease

(2009) Jiyoung Kim et al.   JOURNAL OF NEUROCHEMISTRY

Sulforaphane improves cognitive function administered following traumatic brain injury

(2009) Pramod K. Dash et al.   NEUROSCIENCE LETTERS

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

(2009) K. Kanninen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multitargeted therapy of cancer by green tea polyphenols

(2008) Naghma Khan et al.   CANCER LETTERS

Neuroscience and Hormesis: Overview and General Findings

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Heat Stress and Hormetin-Induced Hormesis in Human Cells: Effects on Aging, Wound Healing, Angiogenesis, and Differentiation

(2008) Suresh I. S. Rattan et al.   Dose-Response

Attenuation of senescence-induced oxidative exacerbations in aged rat brain by (−)-epigallocatechin-3-gallate

(2008) Ravichandran Srividhya et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid

(2008) Katja Kanninen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Kavalactones Protect Neural Cells against Amyloid   Peptide-Induced Neurotoxicity via Extracellular Signal-Regulated Kinase 1/2-Dependent Nuclear Factor Erythroid 2-Related Factor 2 Activation

(2008) C. J. Wruck et al.   MOLECULAR PHARMACOLOGY

Brain foods: the effects of nutrients on brain function

(2008) Fernando Gómez-Pinilla   NATURE REVIEWS NEUROSCIENCE

Botanical Phenolics and Brain Health

(2008) Albert Y. Sun et al.   NEUROMOLECULAR MEDICINE

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA

Alzheimer's disease: new diagnostic and therapeutic tools

(2008) Marco Racchi et al.   Immunity & Ageing

Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease

(2007) Leonel E. Rojo et al.   ARCHIVES OF MEDICAL RESEARCH

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY