The Role of Hydrogen Sulfide in Respiratory Diseases

Highlight article: Hydrogen sulfide alleviates cigarette smoke-induced COPD through inhibition of the TGF-β1/smad pathway

(2020) Liang Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hydrogen Sulfide Attenuates Particulate Matter-Induced Emphysema and Airway Inflammation Through Nrf2-Dependent Manner

(2020) Guohua Jia et al.   Frontiers in Pharmacology

Structure-activity Relationships Study of Isothiocyanates for H2S Releasing Properties: 3-Pyridyl-Isothiocyanate as a New Promising Cardioprotective Agent

(2020) Valentina Citi et al.   Journal of Advanced Research

SG1002 AND CATENATED DIVALENT ORGANIC SULFUR COMPOUNDS AS PROMISING HYDROGEN SULFIDE PRODRUGS

(2020) Gabriel Gojon et al.   ANTIOXIDANTS & REDOX SIGNALING

The effects of gasotransmitters on bronchopulmonary dysplasia

(2020) Hai Lin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Expression of pulmonary arterial elastin in rats with hypoxic pulmonary hypertension using H2S

(2020) Juan Chen et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches

(2020) Valentina Citi et al.   Journal of Advanced Research

Hydrogen Sulfide Ameliorates Lung Ischemia-Reperfusion Injury Through SIRT1 Signaling Pathway in Type 2 Diabetic Rats

(2020) Tao Jiang et al.   Frontiers in Physiology

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1)

(2019) Valentina Citi et al.   PHYTOTHERAPY RESEARCH

A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug

(2019) John L. Wallace et al.   BRITISH JOURNAL OF PHARMACOLOGY

Erucin exhibits vasorelaxing effects and antihypertensive activity by H 2 S‐releasing properties

(2019) Alma Martelli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lymphatic impairment leads to pulmonary tertiary lymphoid organ formation and alveolar damage

(2019) Hasina Outtz Reed et al.   JOURNAL OF CLINICAL INVESTIGATION

H2S attenuates endoplasmic reticulum stress in hypoxia-induced pulmonary artery hypertension

(2019) Jianjun Wu et al.   BIOSCIENCE REPORTS

Biological Effects of Thermal Water-Associated Hydrogen Sulfide on Human Airways and Associated Immune Cells: Implications for Respiratory Diseases

(2019) Joana Viegas et al.   Frontiers in Public Health

Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation

(2019) Da Zhang et al.   CLINICAL SCIENCE

Sulfane sulfur – new findings on an old topic

(2019) Malgorzata Iciek et al.   ACTA BIOCHIMICA POLONICA

Organic Isothiocyanates as Hydrogen Sulfide Donors

(2019) Alma Martelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?

(2019) Simona Sestito et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The role of hydrogen sulfide and H2S-donors in myocardial protection against ischemia/reperfusion injury.

(2018) Valentina Citi et al.   CURRENT MEDICINAL CHEMISTRY

Increased intracellular Cl− concentration promotes ongoing inflammation in airway epithelium

(2018) Yi-Lin Zhang et al.   Mucosal Immunology

Anticancer effect of exogenous hydrogen sulfide in cisplatin‑resistant A549/DDP cells

(2018) Ying Ma et al.   ONCOLOGY REPORTS

Pharmacological Investigation of the Anti-Inflammation and Anti-Oxidation Activities of Diallyl Disulfide in a Rat Emphysema Model Induced by Cigarette Smoke Extract

(2018) Yan Liu et al.   Nutrients

Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H2 S release in vivo

(2018) Elena Lucarini et al.   PHYTOTHERAPY RESEARCH

Chemopreventive activity of sulforaphane

(2018) Xin Jiang et al.   Drug Design Development and Therapy

Hydrogen sulfide limits neutrophil transmigration, inflammation, and oxidative burst in lipopolysaccharide-induced acute lung injury

(2018) Simone Faller et al.   Scientific Reports

Dexamethasone ameliorates H2S-induced acute lung injury by increasing claudin-5 expression via the PI3K pathway

(2017) P Geng et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Hydrogen Sulfide Exerts Anti-oxidative and Anti-inflammatory Effects in Acute Lung Injury

(2017) Kornelia K. Zimmermann et al.   INFLAMMATION

Toward Hydrogen Sulfide Based Therapeutics: Critical Drug Delivery and Developability Issues

(2017) Yueqin Zheng et al.   MEDICINAL RESEARCH REVIEWS

Hydrogen Sulfide Prevents Formation of Reactive Oxygen Species through PI3K/Akt Signaling and Limits Ventilator-Induced Lung Injury

(2017) Sashko Georgiev Spassov et al.   Oxidative Medicine and Cellular Longevity

International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H 2 S Levels: H 2 S Donors and H 2 S Biosynthesis Inhibitors

(2017) Csaba Szabo et al.   PHARMACOLOGICAL REVIEWS

Complementary roles of gasotransmitters CO and H2S in sleep apnea

(2017) Ying-Jie Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ammonium tetrathiomolybdate following ischemia/reperfusion injury: Chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury models

(2017) Alex Dyson et al.   PLOS MEDICINE

Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-κB signaling pathways

(2017) Dongdong Wu et al.   Scientific Reports

Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation

(2017) Wenqi Meng et al.   Scientific Reports

Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations

(2016) Carolin Fleischmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor

(2016) Shi Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

H2S biosynthesis and catabolism: new insights from molecular studies

(2016) Peter Rose et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

H2S Attenuates LPS-Induced Acute Lung Injury by Reducing Oxidative/Nitrative Stress and Inflammation

(2016) Hong-Xia Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Increased glutathione levels contribute to the beneficial effects of hydrogen sulfide and inducible nitric oxide inhibition in allergic lung inflammation

(2016) Daiana Campos et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hydrogen sulfide is a novel potential virulence factor ofMycoplasma pneumoniae: characterization of the unusual cysteine desulfurase/desulfhydrase HapE

(2016) Stephanie Großhennig et al.   MOLECULAR MICROBIOLOGY

Epithelial Electrolyte Transport Physiology and the Gasotransmitter Hydrogen Sulfide

(2016) Ervice Pouokam et al.   Oxidative Medicine and Cellular Longevity

Both the H 2 S biosynthesis inhibitor aminooxyacetic acid and the mitochondrially targeted H 2 S donor AP39 exert protective effects in a mouse model of burn injury

(2016) Akbar Ahmad et al.   PHARMACOLOGICAL RESEARCH

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

(2016) Guoxiang Yuan et al.   Science Signaling

Zofenopril Protects Against Myocardial Ischemia–Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability

(2016) Erminia Donnarumma et al.   Journal of the American Heart Association

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

(2016) Guoxiang Yuan et al.   Science Signaling

Emerging Roles of Hydrogen Sulfide in Inflammatory and Neoplastic Colonic Diseases

(2016) Fang-Fang Guo et al.   Frontiers in Physiology

The protective effect of hydrogen sulfide on systemic sclerosis associated skin and lung fibrosis in mice model

(2016) Zhi Wang et al.   SpringerPlus

Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis

(2016) Ravinder Reddy Gaddam et al.   PLoS One

Inhibitory Effect of Hydrogen Sulfide on Ozone-Induced Airway Inflammation, Oxidative Stress, and Bronchial Hyperresponsiveness

(2015) Pengyu Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications

(2015) Ravinder Kodela et al.   BIOCHEMICAL PHARMACOLOGY

H2S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells

(2015) YoungJun Ju et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

(2015) David J. Polhemus et al.   Cardiovascular Therapeutics

Using hydrogen sulfide to design and develop drugs

(2015) Vincenzo Calderone et al.   Expert Opinion on Drug Discovery

Role of cystathionine β-synthase in human breast Cancer

(2015) Suvajit Sen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Hydrogen Sulfide in Paramyxovirus Infections

(2015) Hui Li et al.   JOURNAL OF VIROLOGY

Gasotransmitters in cancer: from pathophysiology to experimental therapy

(2015) Csaba Szabo   NATURE REVIEWS DRUG DISCOVERY

Role of Hydrogen Sulfide in Ischemia-Reperfusion Injury

(2015) Dongdong Wu et al.   Oxidative Medicine and Cellular Longevity

Hydrogen Sulfide: A Therapeutic Candidate for Fibrotic Disease?

(2015) Kai Song et al.   Oxidative Medicine and Cellular Longevity

Hydrogen Sulfide as a Potential Therapeutic Target in Fibrosis

(2015) Shufang Zhang et al.   Oxidative Medicine and Cellular Longevity

Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation

(2015) Fiorentina Roviezzo et al.   PHARMACOLOGICAL RESEARCH

Pediatric Cystic Fibrosis Sputum Can Be Chemically Dynamic, Anoxic, and Extremely Reduced Due to Hydrogen Sulfide Formation

(2015) Elise S. Cowley et al.   mBio

Protective effects of hydrogen sulfide inhalation on oxidative stress in rats with cotton smoke inhalation-induced lung injury

(2015) ZHI-HAI HAN et al.   Experimental and Therapeutic Medicine

NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties

(2015) Khosrow Kashfi et al.   Redox Biology

Systemic hydrogen sulfide administration partially restores normal alveolarization in an experimental animal model of bronchopulmonary dysplasia

(2014) Alicia Madurga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sodium Thiosulfate Attenuates Acute Lung Injury in Mice

(2014) Masahiro Sakaguchi et al.   ANESTHESIOLOGY

CaMKKβ-Dependent Activation of AMP-Activated Protein Kinase Is Critical to Suppressive Effects of Hydrogen Sulfide on Neuroinflammation

(2014) Xiaomei Zhou et al.   ANTIOXIDANTS & REDOX SIGNALING

H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal KATP channel

(2014) Robert Fitzgerald et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cellular mechanism underlying hydrogen sulfide induced mouse tracheal smooth muscle relaxation: Role of BKCa

(2014) Jiehong Huang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Impact of theophylline/corticosteroid combination therapy on sputum hydrogen sulfide levels in patients with COPD

(2014) P. A. Kirkham et al.   EUROPEAN RESPIRATORY JOURNAL

Global burden of asthma among children

(2014) I. Asher et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Inhibitory effects of hydrogen sulphide on pulmonary fibrosis in smoking ratsviaattenuation of oxidative stress and inflammation

(2014) Xiang Zhou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

H2S during circulatory shock: Some unresolved questions

(2014) Oscar McCook et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro

(2014) Bartosz Szczesny et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effect of S-adenosyl-l-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro

(2014) Katalin Módis et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

The global burden of respiratory disease-Impact on child health

(2014) Heather J. Zar et al.   PEDIATRIC PULMONOLOGY

Role of the cystathionineγlyase/hydrogen sulfide pathway in human melanoma progression

(2014) Elisabetta Panza et al.   Pigment Cell & Melanoma Research

Hydrogen Sulfide Releasing Capacity of Natural Isothiocyanates: Is It a Reliable Explanation for the Multiple Biological Effects of Brassicaceae?

(2014) Valentina Citi et al.   PLANTA MEDICA

Exogenous Hydrogen Sulfide (H2S) Protects Alveolar Growth in Experimental O2-Induced Neonatal Lung Injury

(2014) Arul Vadivel et al.   PLoS One

Actions of Hydrogen Sulfide on Sodium Transport Processes across Native Distal Lung Epithelia (Xenopus laevis)

(2014) Alexandra Erb et al.   PLoS One

Dexamethasone Ameliorates H2S-Induced Acute Lung Injury by Alleviating Matrix Metalloproteinase-2 and -9 Expression

(2014) Jun Wang et al.   PLoS One

Genetic Targets of Hydrogen Sulfide in Ventilator-Induced Lung Injury – A Microarray Study

(2014) Sashko Spassov et al.   PLoS One

Exhaled Hydrogen Sulfide Predicts Airway Inflammation Phenotype in COPD

(2014) J. Zhang et al.   Respiratory Care

Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma

(2014) Jing Zhang et al.   RESPIROLOGY

Sputum-to-serum hydrogen sulfide ratio in COPD

(2014) Junpei Saito et al.   THORAX

Hydrogen sulfide donors in research and drug development

(2014) Zhi Jian Song et al.   MedChemComm

Sodium hydrosulfide alleviates lung inflammation and cell apoptosis following resuscitated hemorrhagic shock in rats

(2013) Dun-quan Xu et al.   ACTA PHARMACOLOGICA SINICA

The Inhibitory Role of Hydrogen Sulfide in Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma

(2013) Gensheng Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Thiosulfate: a readily accessible source of hydrogen sulfide in oxygen sensing

(2013) Kenneth R. Olson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Chemical aspects of hydrogen sulfide measurements in physiological samples

(2013) Péter Nagy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

KATP channels of parafacial respiratory group (pFRG) neurons are involved in H2S-mediated central inhibition of respiratory rhythm in medullary slices of neonatal rats

(2013) Li Chen et al.   BRAIN RESEARCH

Hydrogen sulphide inhibits Ca2+release through InsP3receptors and relaxes airway smooth muscle

(2013) Isabel Castro-Piedras et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sodium Hydrosulphide Alleviates Remote Lung Injury Following Limb Traumatic Injury in Rats

(2013) Jiaolin Ning et al.   PLoS One

Hydrogen Sulfide Donor NaHS Reduces Organ Injury in a Rat Model of Pneumococcal Pneumosepsis, Associated with Improved Bio-Energetic Status

(2013) Hamid Aslami et al.   PLoS One

Cystathionine Beta-Synthase (CBS) Contributes to Advanced Ovarian Cancer Progression and Drug Resistance

(2013) Sanjib Bhattacharyya et al.   PLoS One

Tumor-derived hydrogen sulfide, produced by cystathionine- -synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

(2013) C. Szabo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

(2013) Alma Martelli et al.   ACS Medicinal Chemistry Letters

Could hydrogen sulfide be the next blockbuster treatment for inflammatory disease?

(2013) Ling Li et al.   Expert Review of Clinical Pharmacology

Intoxication accidentelle grave à l’hydrogène sulfuré : un cas pédiatrique de survie

(2012) I. Claudet et al.   ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION

Hydrogen sulphide-induced relaxation of porcine peripheral bronchioles

(2012) S Rashid et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhaled hydrogen sulfide improves graft function in an experimental model of lung transplantation

(2012) Timothy J. George et al.   JOURNAL OF SURGICAL RESEARCH

Inhibition of hydrogen sulfide generation contributes to lung injury after experimental orthotopic lung transplantation

(2012) Jingxiang Wu et al.   JOURNAL OF SURGICAL RESEARCH

Hydrogen Sulfide-Linked Sulfhydration of NF-κB Mediates Its Antiapoptotic Actions

(2012) Nilkantha Sen et al.   MOLECULAR CELL

Correlation between serum H2S and pulmonary function in children with bronchial asthma

(2012) MAN TIAN et al.   Molecular Medicine Reports

The conversion of H2S to sulfane sulfur

(2012) John I. Toohey   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

(2012) C. Coletta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Sulfide Inhibits Proliferation and Release of IL-8 from Human Airway Smooth Muscle Cells

(2011) Mark M. Perry et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sulfur signaling: Is the agent sulfide or sulfane?

(2011) John I. Toohey   ANALYTICAL BIOCHEMISTRY

Protective and Detrimental Effects of Sodium Sulfide and Hydrogen Sulfide in Murine Ventilator-induced Lung Injury

(2011) Roland C. Francis et al.   ANESTHESIOLOGY

Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in Mice

(2011) Weihong Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Myocardial and lung injuries induced by hydrogen sulfide and the effectiveness of oxygen therapy in rats

(2011) Na Wu et al.   CLINICAL TOXICOLOGY

Hydrogen sulfide gas has cell growth regulatory role

(2011) Rajamanickam Baskar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrogen sulfide and asthma

(2011) Peipei Wang et al.   EXPERIMENTAL PHYSIOLOGY

Precursors and inhibitors of hydrogen sulfide synthesis affect acute hypoxic pulmonary vasoconstriction in the intact lung

(2011) Jane A. Madden et al.   JOURNAL OF APPLIED PHYSIOLOGY

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(2011) Jochen Grommes et al.   MOLECULAR MEDICINE

Hydrogen Sulfide and Neurogenic Inflammation in Polymicrobial Sepsis: Involvement of Substance P and ERK-NF-κB Signaling

(2011) Seah-Fang Ang et al.   PLoS One

Inhaled Hydrogen Sulfide Protects against Ventilator-induced Lung Injury

(2010) Simone Faller et al.   ANESTHESIOLOGY

Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346)

(2010) John L Wallace et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hydrogen sulphide and angiogenesis: mechanisms and applications

(2010) Csaba Szabó et al.   BRITISH JOURNAL OF PHARMACOLOGY

Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung

(2010) Ya-Hong Chen et al.   CYTOKINE

Suspended animation inducer hydrogen sulfide is protective in an in vivo model of ventilator-induced lung injury

(2010) Hamid Aslami et al.   INTENSIVE CARE MEDICINE

Do obstructive and restrictive lung diseases share common underlying mechanisms of breathlessness?

(2010) Giorgio Scano et al.   RESPIRATORY MEDICINE

Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising

(2010) Matthew Whiteman et al.   Expert Review of Clinical Pharmacology

The Hydrogen Sulfide Donor NaHS Promotes Angiogenesis in a Rat Model of Hind Limb Ischemia

(2009) Ming-Jie Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

The Effect of Hydrogen Sulfide Donors on Lipopolysaccharide-Induced Formation of Inflammatory Mediators in Macrophages

(2009) Matthew Whiteman et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Sulfide Increases Glutathione Production and Suppresses Oxidative Stress in Mitochondria

(2009) Yuka Kimura et al.   ANTIOXIDANTS & REDOX SIGNALING

Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn- and smoke-induced acute lung injury

(2009) Aimalohi Esechie et al.   BRITISH JOURNAL OF PHARMACOLOGY

GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat

(2009) Ling Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of hydrogen sulfide on inflammation in caerulein-induced acute pancreatitis

(2009) Jenab N Sidhapuriwala et al.   Journal of Inflammation-London

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Hydrogen sulfide regulates lung tissue-oxidized glutathione and total antioxidant capacity in hypoxic pulmonary hypertensive rats

(2008) Hong-ling WEI et al.   ACTA PHARMACOLOGICA SINICA

Lymphatics in Lung Disease

(2008) Souheil El-Chemaly et al.   Annals of the New York Academy of Sciences

A Source of Hydrogen Sulfide and a Mechanism of Its Release in the Brain

(2008) Mari Ishigami et al.   ANTIOXIDANTS & REDOX SIGNALING

H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G

(2008) S Muzaffar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation

(2008) Aimalohi Esechie et al.   CLINICAL SCIENCE

Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma

(2008) Ya-Hong Chen et al.   CYTOKINE

Regulatory Effects of Hydrogen Sulfide on IL-6, IL-8 and IL-10 Levels in the Plasma and Pulmonary Tissue of Rats with Acute Lung Injury

(2008) Tianshui Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Inhibition of Hydrogen Sulfide Synthesis Attenuates Chemokine Production and Protects Mice Against Acute Pancreatitis and Associated Lung Injury

(2008) Ramasamy Tamizhselvi et al.   PANCREAS

Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis

(2007) S Fiorucci et al.   BRITISH JOURNAL OF PHARMACOLOGY