Mechanisms of Oocyte Maturation and Related Epigenetic Regulation

HDAC11 promotes meiotic apparatus assembly during mouse oocyte maturation via decreasing H4K16 and α-tubulin acetylation

(2020) Liyan Sui et al.   CELL CYCLE

Inhibition of HDAC6 by tubastatin A disrupts mouse oocyte meiosis via regulating histone modifications and mRNA expression

(2020) Liyan Sui et al.   JOURNAL OF CELLULAR PHYSIOLOGY

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

(2020) Aditya Sankar et al.   NATURE CELL BIOLOGY

Citrinin exposure disrupts organelle distribution and functions in mouse oocytes

(2020) Ming-Hong Sun et al.   ENVIRONMENTAL RESEARCH

RAB7 GTPase regulates actin dynamics for DRP1‐mediated mitochondria function and spindle migration in mouse oocyte meiosis

(2020) Zhen‐Nan Pan et al.   FASEB JOURNAL

DPAGT1‐Mediated Protein N ‐Glycosylation Is Indispensable for Oocyte and Follicle Development in Mice

(2020) Hui Li et al.   Advanced Science

Function and Regulation of Histone H3 Lysine-4 Methylation During Oocyte Meiosis and Maternal-to-Zygotic Transition

(2020) Qian-Qian Sha et al.   Frontiers in Cell and Developmental Biology

Oocyte-specific deletion of Hdac8 in mice reveals stage-specific effects on fertility

(2019) Vijay Pratap Singh et al.   REPRODUCTION

A story of birth and death: mRNA translation and clearance at the onset of maternal-to-zygotic transition in mammals†

(2019) Qian-Qian Sha et al.   BIOLOGY OF REPRODUCTION

Tubastatin A inhibits HDAC and Sirtuin activity rather than being a HDAC6-specific inhibitor in mouse oocytes

(2019) Yun-Jung Choi et al.   Aging-US

Cyclins regulating oocyte meiotic cell cycle progression

(2019) Jian Li et al.   BIOLOGY OF REPRODUCTION

Transforming growth factor-β is involved in maintaining oocyte meiotic arrest by promoting natriuretic peptide type C expression in mouse granulosa cells

(2019) Jing Yang et al.   Cell Death & Disease

Loss of HDAC3 contributes to meiotic defects in aged oocytes

(2019) Yongfu He et al.   AGING CELL

The CRL4-DCAF13 ubiquitin E3 ligase supports oocyte meiotic resumption by targeting PTEN degradation

(2019) Jue Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Loss of the E2 SUMO-conjugating enzyme Ube2i in oocytes during ovarian folliculogenesis causes infertility in mice

(2019) Amanda Rodriguez et al.   DEVELOPMENT

HDAC3 maintains oocyte meiosis arrest by repressing amphiregulin expression before the LH surge

(2019) Huarong Wang et al.   Nature Communications

C-type natriuretic peptide: a link between hyperandrogenism and anovulation in a mouse model of polycystic ovary syndrome

(2018) Adelina M. Reis et al.   CLINICAL SCIENCE

High level of C-type natriuretic peptide induced by hyperandrogen-mediated anovulation in polycystic ovary syndrome mice

(2018) Xiao Wang et al.   CLINICAL SCIENCE

Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis

(2018) Weber Beringui Feitosa et al.   DEVELOPMENTAL BIOLOGY

Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility

(2018) Carla Tatone et al.   HUMAN REPRODUCTION UPDATE

Histone demethylase KDM4A and KDM4B expression in granulosa cells from women undergoing in vitro fertilization

(2018) Adam J. Krieg et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

MLL2 conveys transcription-independent H3K4 trimethylation in oocytes

(2018) Courtney W. Hanna et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MLL2 conveys transcription-independent H3K4 trimethylation in oocytes

(2018) Courtney W. Hanna et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes

(2018) Qian-Qian Sha et al.   Nature Communications

Involvement of PKCε in FSH-induced connexin43 phosphorylation and oocyte maturation in mouse

(2018) Han Cai et al.   Biology Open

Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing

(2018) Jue Zhang et al.   CELL DEATH AND DIFFERENTIATION

KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer

(2018) Besa Xhabija et al.   SEMINARS IN CANCER BIOLOGY

Maternal mRNAs with distinct 3′ UTRs define the temporal pattern of Ccnb1 synthesis during mouse oocyte meiotic maturation

(2017) Ye Yang et al.   GENES & DEVELOPMENT

Poly(A)-binding proteins are required for translational regulation in vertebrate oocytes and early embryos

(2017) Saffet Ozturk et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Polydatin improves the developmental competence of bovine embryos in vitro via induction of sirtuin 1 (Sirt1)

(2017) Imran Khan et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Natriuretic peptides improve the developmental competence of in vitro cultured porcine oocytes

(2017) Yanhao Zhang et al.   Reproductive Biology and Endocrinology

Estrogen receptors in granulosa cells govern meiotic resumption of pre-ovulatory oocytes in mammals

(2017) Wei Liu et al.   Cell Death & Disease

HDAC8 functions in spindle assembly during mouse oocyte meiosis

(2017) Kemei Zhang et al.   Oncotarget

The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin

(2017) David A. Brown et al.   Cell Reports

CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes

(2017) Chao Yu et al.   Cell Reports

Histone deacetylase 6 (HDAC6) is an essential factor for oocyte maturation and asymmetric division in mice

(2017) Dongjie Zhou et al.   Scientific Reports

Epidermal Growth Factor-Mobilized Intracellular Calcium of Cumulus Cells Decreases Natriuretic Peptide Receptor 2 Affinity for Natriuretic Peptide Type C and Induces Oocyte Meiotic Resumption in the Mouse

(2016) X. Hao et al.   BIOLOGY OF REPRODUCTION

Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of Meiosis1

(2016) Jeremy R. Egbert et al.   BIOLOGY OF REPRODUCTION

Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan

(2016) Deepak Adhikari et al.   CELL RESEARCH

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse

(2016) Chao Yu et al.   CELL RESEARCH

Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone

(2016) Leia C. Shuhaibar et al.   DEVELOPMENTAL BIOLOGY

BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

(2016) Chao Yu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

(2016) Chao Yu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Resveratrol compares with melatonin in improving in vitro porcine oocyte maturation under heat stress

(2016) Yu Li et al.   Journal of Animal Science and Biotechnology

Sirt3 prevents maternal obesity-associated oxidative stress and meiotic defects in mouse oocytes

(2015) Liang Zhang et al.   CELL CYCLE

Estrogenic endocrine disruptors: Molecular mechanisms of action

(2015) Ryoiti Kiyama et al.   ENVIRONMENT INTERNATIONAL

Oocyte maturation: gamete-somatic cells interactions, meiotic resumption, cytoskeletal dynamics and cytoplasmic reorganization

(2015) Giovanni Coticchio et al.   HUMAN REPRODUCTION UPDATE

Nicotinamide Impairs Entry into and Exit from Meiosis I in Mouse Oocytes

(2015) Angelique Riepsamen et al.   PLoS One

Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles

(2015) Leia C. Shuhaibar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resveratrol improves the quality of pig oocytes derived from early antral follicles through sirtuin 1 activation

(2015) N. Itami et al.   THERIOGENOLOGY

LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice

(2015) Jeesun Kim et al.   Nature Communications

Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte

(2015) Longsen Han et al.   Scientific Reports

Cytoplasmic Polyadenylation Element Binding Proteins in Development, Health, and Disease

(2014) Maria Ivshina et al.   Annual Review of Cell and Developmental Biology

Multiple Pathways Mediate Luteinizing Hormone Regulation of cGMP Signaling in the Mouse Ovarian Follicle1

(2014) Xueqing Liu et al.   BIOLOGY OF REPRODUCTION

Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes

(2014) J. R. Egbert et al.   DEVELOPMENT

The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation

(2014) A. S. Bledau et al.   DEVELOPMENT

Sustained Activity of the EGF Receptor Is an Absolute Requisite for LH-Induced Oocyte Maturation and Cumulus Expansion

(2014) Yitzhak Reizel et al.   ENDOCRINE REVIEWS

SIRT1 signalling protects mouse oocytes against oxidative stress and is deregulated during aging

(2014) Giovanna Di Emidio et al.   HUMAN REPRODUCTION

Brain Natriuretic Peptide and C-Type Natriuretic Peptide Maintain Porcine Oocyte Meiotic Arrest

(2014) Wenqiang Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CBP-CITED4 is required for luteinizing hormone-triggered target gene expression during ovulation

(2014) Y.-L. Zhang et al.   MOLECULAR HUMAN REPRODUCTION

Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells

(2014) Fengdong Cheng et al.   MOLECULAR IMMUNOLOGY

SUMO-1 plays crucial roles for spindle organization, chromosome congression, and chromosome segregation during mouse oocyte meiotic maturation

(2014) Yi-Feng Yuan et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Relationship between mitochondrial DNA Copy Number and SIRT1 Expression in Porcine Oocytes

(2014) Daichi Sato et al.   PLoS One

The ubiquitin proteasome system — Implications for cell cycle control and the targeted treatment of cancer

(2013) Florian Bassermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Maternal factors required for oocyte developmental competence in mice: Transcriptome analysis of non-surrounded nucleolus (NSN) and surrounded nucleolus (SN) oocytes

(2013) Jun-Yu Ma et al.   CELL CYCLE

Epidermal Growth Factor Receptor Signaling-Dependent Calcium Elevation in Cumulus Cells Is Required for NPR2 Inhibition and Meiotic Resumption in Mouse Oocytes

(2013) Yakun Wang et al.   ENDOCRINOLOGY

Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosis

(2013) Liang Zhang et al.   FASEB JOURNAL

Beneficial effect of resveratrol on bovine oocyte maturation and subsequent embryonic development after in vitro fertilization

(2013) Feng Wang et al.   FERTILITY AND STERILITY

Resveratrol protects against age-associated infertility in mice

(2013) Mengyuan Liu et al.   HUMAN REPRODUCTION

Resveratrol Improves the Mitochondrial Function and Fertilization Outcome of Bovine Oocytes

(2013) Shun TAKEO et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

The regulation of maturation promoting factor during prophase I arrest and meiotic entry in mammalian oocytes

(2013) Deepak Adhikari et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice

(2013) Arun Gupta et al.   MUTAGENESIS

Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytes

(2013) Jing Chen et al.   NATURE CELL BIOLOGY

The road to maturation: somatic cell interaction and self-organization of the mammalian oocyte

(2013) Rong Li et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone Deacetylase 2 (HDAC2) Regulates Chromosome Segregation and Kinetochore Function via H4K16 Deacetylation during Oocyte Maturation in Mouse

(2013) Pengpeng Ma et al.   PLoS Genetics

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

Hormonal Coordination of Natriuretic Peptide Type C and Natriuretic Peptide Receptor 3 Expression in Mouse Granulosa Cells1

(2012) Kyung-Bon Lee et al.   BIOLOGY OF REPRODUCTION

A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type

(2012) K. A. Geister et al.   HUMAN MOLECULAR GENETICS

CNP/NPR2 signaling maintains oocyte meiotic arrest in early antral follicles and is suppressed by EGFR-mediated signaling in preovulatory follicles

(2012) Takehito Tsuji et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

The G Protein Coupled Receptor 3 Is Involved in cAMP and cGMP Signaling and Maintenance of Meiotic Arrest in Porcine Oocytes

(2012) Cai-Rong Yang et al.   PLoS One

Meiosis arrest female 1 (MARF1) has nuage-like function in mammalian oocytes

(2012) Y.-Q. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development

(2012) P. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MARF1 Regulates Essential Oogenic Processes in Mice

(2012) Y.-Q. Su et al.   SCIENCE

Septin2 is modified by SUMOylation and required for chromosome congression in mouse oocytes

(2011) Jin-Liang Zhu et al.   CELL CYCLE

Hormonal control of mammalian oocyte meiosis at diplotene stage

(2011) Meijia Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transcript clearance during the maternal-to-zygotic transition

(2011) Claudia B Walser et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Inhibition of proteasomal proteolysis affects expression of extracellular matrix components and steroidogenesis in porcine oocyte-cumulus complexes

(2011) E. Nagyova et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition

(2011) J. Chen et al.   GENES & DEVELOPMENT

Pre-ovulatory LH/hCG surge decreases C-type natriuretic peptide secretion by ovarian granulosa cells to promote meiotic resumption of pre-ovulatory oocytes

(2011) K. Kawamura et al.   HUMAN REPRODUCTION

PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells

(2011) Burchell   INTERNATIONAL JOURNAL OF ONCOLOGY

BubR1 Is Modified by Sumoylation during Mitotic Progression

(2011) Feikun Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential role of ubiquitin C-terminal hydrolases UCHL1 and UCHL3 in mammalian oocyte maturation

(2011) Namdori R. Mtango et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Influence of Histone Tails and H4 Tail Acetylations on Nucleosome–Nucleosome Interactions

(2011) Ying Liu et al.   JOURNAL OF MOLECULAR BIOLOGY

Novel signaling mechanisms in the ovary during oocyte maturation and ovulation

(2011) Marco Conti et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The United States of Histone Ubiquitylation and Methylation

(2011) Michael Werner et al.   MOLECULAR CELL

Hdac6 Knock-Out Increases Tubulin Acetylation but Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease

(2011) Anna Bobrowska et al.   PLoS One

Genetic Dissection of Epidermal Growth Factor Receptor Signaling during Luteinizing Hormone-Induced Oocyte Maturation

(2011) Minnie Hsieh et al.   PLoS One

The biology and dynamics of mammalian cortical granules

(2011) Min Liu   Reproductive Biology and Endocrinology

Role of Ubiquitin C-Terminal Hydrolase-L1 in Antipolyspermy Defense of Mammalian Oocytes1

(2010) Andrej Susor et al.   BIOLOGY OF REPRODUCTION

Dynamics of histone H4 acetylation during the cell cycle

(2010) Miglena A. Koprinarova et al.   CELL CYCLE

Covalent modifications of histones during mitosis and meiosis

(2010) Dazhong Xu et al.   CELL CYCLE

The SUMO pathway functions in mouse oocyte maturation

(2010) Zhen-Bo Wang et al.   CELL CYCLE

BubR1 is a spindle assembly checkpoint protein regulating meiotic cell cycle progression of mouse oocyte

(2010) Liang Wei et al.   CELL CYCLE

Histone modifications during mammalian oocyte maturation: Dynamics, regulation and functions

(2010) Ling Gu et al.   CELL CYCLE

Spatial regulation of APCCdh1-induced cyclin B1 degradation maintains G2 arrest in mouse oocytes

(2010) J. E. Holt et al.   DEVELOPMENT

Hdac1 and Hdac2 Act Redundantly to Control p63 and p53 Functions in Epidermal Progenitor Cells

(2010) Matthew LeBoeuf et al.   DEVELOPMENTAL CELL

Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation

(2010) Alvaro Rada-Iglesias et al.   Epigenetics

Prophase I arrest and progression to metaphase I in mouse oocytes: comparison of resumption of meiosis and recovery from G2-arrest in somatic cells

(2010) P. Solc et al.   MOLECULAR HUMAN REPRODUCTION

Mechanisms contributing to the reduced developmental competence of glucosamine-exposed mouse oocytes

(2010) Cheryl J. Schelbach et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Granulosa Cell Ligand NPPC and Its Receptor NPR2 Maintain Meiotic Arrest in Mouse Oocytes

(2010) M. Zhang et al.   SCIENCE

MLL2 Is Required in Oocytes for Bulk Histone 3 Lysine 4 Trimethylation and Transcriptional Silencing

(2010) Claudia V. Andreu-Vieyra et al.   PLOS BIOLOGY

Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte

(2009) R. P. Norris et al.   DEVELOPMENT

DUBs at a glance

(2009) K. D. Wilkinson   JOURNAL OF CELL SCIENCE

The signal pathway of gonadotrophins-induced mammalian oocyte meiotic resumption

(2009) M. Zhang et al.   MOLECULAR HUMAN REPRODUCTION

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

(2009) David N. Ciccone et al.   NATURE

Master Regulators of Female Fertility

(2009) Nava Dekel   NEW ENGLAND JOURNAL OF MEDICINE

MAPK3/1 (ERK1/2) in Ovarian Granulosa Cells Are Essential for Female Fertility

(2009) H.-Y. Fan et al.   SCIENCE

UBE2I (UBC9), a SUMO-Conjugating Enzyme, Localizes to Nuclear Speckles and Stimulates Transcription in Mouse Oocytes1

(2008) Motomasa Ihara et al.   BIOLOGY OF REPRODUCTION

Generation of mouse oocytes defective in cAMP synthesis and degradation: Endogenous cyclic AMP is essential for meiotic arrest

(2008) Sergio Vaccari et al.   DEVELOPMENTAL BIOLOGY

Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos

(2008) Pengpeng Ma et al.   DEVELOPMENTAL BIOLOGY

Oocyte-specific G-protein–coupled receptor 3 (GPR3): no perturbations found in 82 women with premature ovarian failure (first report)

(2008) Ertug Kovanci et al.   FERTILITY AND STERILITY

Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

(2008) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control

(2008) Srividya Bhaskara et al.   MOLECULAR CELL

Securin regulates entry into M-phase by modulating the stability of cyclin B

(2008) Petros Marangos et al.   NATURE CELL BIOLOGY

Characterization of the post-translational modification of recombinant human BMP-15 mature protein

(2008) Seiji Saito et al.   PROTEIN SCIENCE

Gap junctions in the ovary: Expression, localization and function

(2007) Eran Gershon et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY