A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type

Achondroplasia: Manifestations and Treatment

(2016) Eric D. Shirley et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Exome Sequencing Identifies PDE4D Mutations in Acrodysostosis

(2012) Hane Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Novel mutations in natriuretic peptide receptor-2 gene underlie acromesomelic dysplasia, type maroteaux

(2012) Saadullah Khan et al.   BMC Medical Genetics

Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome

(2012) Valerie A Arboleda et al.   NATURE GENETICS

NPPC/NPR2 signaling is essential for oocyte meiotic arrest and cumulus oophorus formation during follicular development in the mouse ovary

(2012) Chiyo Kiyosu et al.   REPRODUCTION

Nosology and classification of genetic skeletal disorders: 2010 revision

(2011) Matthew L. Warman et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Pilot study of PD-0325901 in previously treated patients with advanced melanoma, breast cancer, and colon cancer

(2011) Peter D. Boasberg et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Guanylyl cyclase structure, function and regulation

(2011) Lincoln R. Potter   CELLULAR SIGNALLING

Sixteen years and counting: The current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias

(2011) Silvie Foldynova-Trantirkova et al.   HUMAN MUTATION

The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

(2011) E J Mackie et al.   JOURNAL OF ENDOCRINOLOGY

Lack of HIF-2α in limb bud mesenchyme causes a modest and transient delay of endochondral bone development

(2011) Elisa Araldi et al.   NATURE MEDICINE

A MEK Inhibitor Abrogates Myeloproliferative Disease in Kras Mutant Mice

(2011) N. Lyubynska et al.   Science Translational Medicine

Gastrointestinal Tract Disorder in Natriuretic Peptide Receptor B Gene Mutant Mice

(2010) Chizuru Sogawa et al.   AMERICAN JOURNAL OF PATHOLOGY

Signaling Pathways in Human Skeletal Dysplasias

(2010) Dustin Baldridge et al.   Annual Review of Genomics and Human Genetics

Towards a new understanding on the regulation of mammalian oocyte meiosis resumption

(2010) Qing-Yuan Sun et al.   CELL CYCLE

A Phase II Study of PD-0325901, an Oral MEK Inhibitor, in Previously Treated Patients with Advanced Non-Small Cell Lung Cancer

(2010) E. B. Haura et al.   CLINICAL CANCER RESEARCH

Translational research of C-type natriuretic peptide (CNP) into skeletal dysplasias

(2010) Akihiro Yasoda et al.   ENDOCRINE JOURNAL

The skeletal dysplasias

(2010) Deborah Krakow et al.   GENETICS IN MEDICINE

Granulosa Cell Ligand NPPC and Its Receptor NPR2 Maintain Meiotic Arrest in Mouse Oocytes

(2010) M. Zhang et al.   SCIENCE

Genetic Control of Bone Formation

(2009) Gerard Karsenty et al.   Annual Review of Cell and Developmental Biology

Cyclic GMP Signaling Is Involved in the Luteinizing Hormone-Dependent Meiotic Maturation of Mouse Oocytes1

(2009) Sergio Vaccari et al.   BIOLOGY OF REPRODUCTION

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

(2009) K. N. Retting et al.   DEVELOPMENT

Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte

(2009) R. P. Norris et al.   DEVELOPMENT

Systemic Administration of C-Type Natriuretic Peptide as a Novel Therapeutic Strategy for Skeletal Dysplasias

(2009) Akihiro Yasoda et al.   ENDOCRINOLOGY

Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, αT3-1 and LβT2 gonadotroph cells

(2009) Iain R Thompson et al.   JOURNAL OF ENDOCRINOLOGY

The signal pathway of gonadotrophins-induced mammalian oocyte meiotic resumption

(2009) M. Zhang et al.   MOLECULAR HUMAN REPRODUCTION

Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras

(2009) Jennifer O. Lauchle et al.   NATURE

FGFs in endochondral skeletal development

(2009) William A. Horton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Pubertal Development and Menarche

(2008) Sara A. DiVall et al.   Annals of the New York Academy of Sciences

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901

(2008) Stephen D. Barrett et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cellular and molecular aspects of ovarian follicle ageing

(2008) Carla Tatone et al.   HUMAN REPRODUCTION UPDATE

Luteinizing Hormone Signaling in Preovulatory Follicles Involves Early Activation of the Epidermal Growth Factor Receptor Pathway

(2008) Sara Panigone et al.   MOLECULAR ENDOCRINOLOGY

The biology of infertility: research advances and clinical challenges

(2008) Martin M Matzuk et al.   NATURE MEDICINE

Fetal Skeletal Dysplasia: An Approach to Diagnosis with Illustrative Cases

(2008) Manjiri Dighe et al.   RADIOGRAPHICS

The receptor attributable to C-type natriuretic peptide-induced differentiation of osteoblasts is switched from type B- to type C-natriuretic peptide receptor with aging

(2007) Hiroyuki Kaneki et al.   JOURNAL OF CELLULAR BIOCHEMISTRY