In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii

Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in E. coli Nissle Residing in the Mammalian Gut

(2020) Nathan Crook et al.   ACS Synthetic Biology

Treatment of murine colitis by Saccharomyces boulardii secreting atrial natriuretic peptide

(2020) Cheng-Hao Liu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans

(2019) Caroline B. Kurtz et al.   Science Translational Medicine

Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection

(2019) Johanna M. Sweere et al.   SCIENCE

The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases

(2019) Mathias L. Richard et al.   Nature Reviews Gastroenterology & Hepatology

A new genomic blueprint of the human gut microbiota

(2019) Alexandre Almeida et al.   NATURE

Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut

(2019) Nathan Crook et al.   Cell Host & Microbe

Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses

(2019) Tzu-Yu Shao et al.   Cell Host & Microbe

Genetically engineered probiotic Saccharomyces cerevisiae strains mature human dendritic cells and stimulate Gag-specific memory CD8+ T cells ex vivo

(2019) Mariana L. Palma et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering a Model Cell for Rational Tuning of GPCR Signaling

(2019) William M. Shaw et al.   CELL

Stepwise Development of an in vitro Continuous Fermentation Model for the Murine Caecal Microbiota

(2019) Sophie A. Poeker et al.   Frontiers in Microbiology

Overcoming genetic heterogeneity in industrial fermentations

(2019) Peter Rugbjerg et al.   NATURE BIOTECHNOLOGY

All-trans Retinoic Acid Counteracts Diarrhea and Inhibition of Downregulated in Adenoma Expression in Gut Inflammation

(2019) Shubha Priyamvada et al.   INFLAMMATORY BOWEL DISEASES

Implementing CRISPR-Cas technologies in conventional and non-conventional yeasts: Current state and future prospects

(2018) Hana Raschmanová et al.   BIOTECHNOLOGY ADVANCES

Multiscale Evolutionary Dynamics of Host-Associated Microbiomes

(2018) Aura Ferreiro et al.   CELL

An innovative cell-printed microscale collagen model for mimicking intestinal villus epithelium

(2018) WonJin Kim et al.   CHEMICAL ENGINEERING JOURNAL

Engineered commensal microbes for diet-mediated colorectal-cancer chemoprevention

(2018) Chun Loong Ho et al.   Nature Biomedical Engineering

Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts

(2018) Raymond W. Bourdeau et al.   NATURE

Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria

(2018) Vincent M Isabella et al.   NATURE BIOTECHNOLOGY

Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

(2018) Fabien Duveau et al.   eLife

Synthetic Biology and Engineered Live Biotherapeutics: Toward Increasing System Complexity

(2018) Tanel Ozdemir et al.   Cell Systems

Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow

(2018) Elizabeth Brunk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental evolution of a fungal pathogen into a gut symbiont

(2018) Gloria Hoi Wan Tso et al.   SCIENCE

Engineering Microbial Living Therapeutics: The Synthetic Biology Toolbox

(2018) Danielle B. Pedrolli et al.   TRENDS IN BIOTECHNOLOGY

A System for Gene Expression Noise Control in Yeast

(2018) Max Mundt et al.   ACS Synthetic Biology

Comprehensive Profiling of Four Base Overhang Ligation Fidelity by T4 DNA Ligase and Application to DNA Assembly

(2018) Vladimir Potapov et al.   ACS Synthetic Biology

Mouse Microbiota Models: Comparing Germ-Free Mice and Antibiotics Treatment as Tools for Modifying Gut Bacteria

(2018) Elizabeth A. Kennedy et al.   Frontiers in Physiology

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

(2017) David T Riglar et al.   NATURE BIOTECHNOLOGY

CRISPR/Cpf1 enables fast and simple genome editing of Saccharomyces cerevisiae

(2017) René Verwaal et al.   YEAST

Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models

(2017) In Young Hwang et al.   Nature Communications

Next-generation probiotics: the spectrum from probiotics to live biotherapeutics

(2017) Paul W. O’Toole et al.   Nature Microbiology

Complete genome sequence and comparative genomics of the probiotic yeast Saccharomyces boulardii

(2017) Indu Khatri et al.   Scientific Reports

Culturomics and Amplicon-based Metagenomic Approaches for the Study of Fungal Population in Human Gut Microbiota

(2017) Ibrahim Hamad et al.   Scientific Reports

Microbiome therapeutics — Advances and challenges

(2016) Mark Mimee et al.   ADVANCED DRUG DELIVERY REVIEWS

Metabolic Engineering of Probiotic Saccharomyces boulardii

(2016) Jing-Jing Liu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Immunological Consequences of Intestinal Fungal Dysbiosis

(2016) Matthew L. Wheeler et al.   Cell Host & Microbe

Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis

(2016) Yi Xiao et al.   Nature Chemical Biology

A Cas9-based toolkit to program gene expression inSaccharomyces cerevisiae

(2016) Amanda Reider Apel et al.   NUCLEIC ACIDS RESEARCH

Characterization of the Probiotic Yeast Saccharomyces boulardii in the Healthy Mucosal Immune System

(2016) Lauren E. Hudson et al.   PLoS One

A microfluidics-based in vitro model of the gastrointestinal human–microbe interface

(2016) Pranjul Shah et al.   Nature Communications

Robust Synthetic Circuits for Two-Dimensional Control of Gene Expression in Yeast

(2016) Andrés Aranda-Díaz et al.   ACS Synthetic Biology

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Engineering Rhodosporidium toruloides with a membrane transporter facilitates production and separation of carotenoids and lipids in a bi-phasic culture

(2015) Jaslyn J.L Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The Characterization of Feces and Urine: A Review of the Literature to Inform Advanced Treatment Technology

(2015) C. Rose et al.   CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY

Comparative Analysis of Intestinal Tract Models

(2015) C.F. Williams et al.   Annual Review of Food Science and Technology

A Highly Characterized Yeast Toolkit for Modular, Multipart Assembly

(2015) Michael E. Lee et al.   ACS Synthetic Biology

Violacein: Properties and Production of a Versatile Bacterial Pigment

(2015) Seong Yeol Choi et al.   Biomed Research International

A system for multilocus chromosomal integration and transformation-free selection marker rescue

(2014) Michael S. Siddiqui et al.   FEMS YEAST RESEARCH

3-D Intestinal Scaffolds for Evaluating the Therapeutic Potential of Probiotics

(2014) Cait M. Costello et al.   MOLECULAR PHARMACEUTICS

Programmable bacteria detect and record an environmental signal in the mammalian gut

(2014) Jonathan W. Kotula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial Assembly of Large Biochemical Pathways into Yeast Chromosomes for Improved Production of Value-added Compounds

(2014) Jifeng Yuan et al.   ACS Synthetic Biology

Use of expression-enhancing terminators in Saccharomyces cerevisiae to increase mRNA half-life and improve gene expression control for metabolic engineering applications

(2013) Kathleen A. Curran et al.   METABOLIC ENGINEERING

Determinants of nucleosome positioning

(2013) Kevin Struhl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay

(2013) Michael E. Lee et al.   NUCLEIC ACIDS RESEARCH

A Genome-Wide Activity Assessment of Terminator Regions in Saccharomyces cerevisiae Provides a ″Terminatome″ Toolbox

(2013) Mamoru Yamanishi et al.   ACS Synthetic Biology

On chip porous polymer membranes for integration of gastrointestinal tract epithelium with microfluidic ‘body-on-a-chip’ devices

(2012) Mandy Brigitte Esch et al.   BIOMEDICAL MICRODEVICES

Characterization of plasmid burden and copy number inSaccharomyces cerevisiaefor optimization of metabolic engineering applications

(2012) Ashty S. Karim et al.   FEMS YEAST RESEARCH

Quantitative Phenotyping of Inflammatory Bowel Disease in the IL-10-deficient Mouse by Use of Noninvasive Magnetic Resonance Imaging

(2012) Svenja Michael et al.   INFLAMMATORY BOWEL DISEASES

Adhesion to the yeast cell surface as a mechanism for trapping pathogenic bacteria by Saccharomyces probiotics

(2012) F. C. P. Tiago et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Re-engineering multicloning sites for function and convenience

(2011) Nathan C. Crook et al.   NUCLEIC ACIDS RESEARCH

Reiterative Recombination for the in vivo assembly of libraries of multigene pathways

(2011) L. M. Wingler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterologous carotenoid production in Saccharomyces cerevisiae induces the pleiotropic drug resistance stress response

(2010) René Verwaal et al.   YEAST

Characterization of chromosomal integration sites for heterologous gene expression inSaccharomyces cerevisiae

(2009) Dongmei Bai Flagfeldt et al.   YEAST

Molecular analysis of the digestive microbiota in a gnotobiotic mouse model during antibiotic treatment: Influence of Saccharomyces boulardii

(2008) Marie-Claude Barc et al.   ANAEROBE