An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

(2017) David T Riglar et al.   NATURE BIOTECHNOLOGY

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition

(2016) Mark R. Charbonneau et al.   CELL

Arginine Metabolism Revisited

(2016) Sidney M Morris   JOURNAL OF NUTRITION

Safety and Effectiveness of Arginine in Adults

(2016) Catherine J McNeal et al.   JOURNAL OF NUTRITION

Systematic Review: Adverse Events of Fecal Microbiota Transplantation

(2016) Sinan Wang et al.   PLoS One

Covert and Overt Hepatic Encephalopathy: Diagnosis and Management

(2015) Kavish R. Patidar et al.   Clinical Gastroenterology and Hepatology

Engineered Commensal Bacteria Reprogram Intestinal Cells Into Glucose-Responsive Insulin-Secreting Cells for the Treatment of Diabetes

(2015) Franklin F. Duan et al.   DIABETES

The Epidemiology of Cirrhosis in the United States

(2015) Steven Scaglione et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Engineering the gut microbiota to treat hyperammonemia

(2015) Ting-Chin David Shen et al.   JOURNAL OF CLINICAL INVESTIGATION

Standard Operating Procedures in Experimental Liver Research: Thioacetamide model in mice and rats

(2015) MC Wallace et al.   LABORATORY ANIMALS

Refining the Ammonia Hypothesis

(2015) Elliot B. Tapper et al.   MAYO CLINIC PROCEEDINGS

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Temporal trends in population-based death rates associated with chronic liver disease and liver cancer in the United States over the last 30 years

(2014) Yuhree Kim et al.   CANCER

Probiotic VSL#3 Reduces Liver Disease Severity and Hospitalization in Patients With Cirrhosis: A Randomized, Controlled Trial

(2014) Radha K. Dhiman et al.   GASTROENTEROLOGY

Global Transcriptional Start Site Mapping Using Differential RNA Sequencing Reveals Novel Antisense RNAs in Escherichia coli

(2014) Maureen K. Thomason et al.   JOURNAL OF BACTERIOLOGY

Complete genome sequence of the Gram-negative probiotic Escherichia coli strain Nissle 1917

(2014) Marten Reister et al.   JOURNAL OF BIOTECHNOLOGY

Kinetics of the utilization of dietary arginine for nitric oxide and urea synthesis: insight into the arginine–nitric oxide metabolic system in humans

(2013) François Mariotti et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Phase 1b, multicenter, single blinded, placebo-controlled, sequential dose escalation study to assess the safety and tolerability of topically applied AG013 in subjects with locally advanced head and neck cancer receiving induction chemotherapy

(2013) Sewanti Atul Limaye et al.   CANCER

Oral Delivery of IL-27 Recombinant Bacteria Attenuates Immune Colitis in Mice

(2013) Miranda L. Hanson et al.   GASTROENTEROLOGY

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Suggested guidelines for the diagnosis and management of urea cycle disorders

(2012) Johannes Häberle et al.   Orphanet Journal of Rare Diseases

A double-blind placebo-controlled trial to study therapeutic effects of probiotic Escherichia coli Nissle 1917 in subgroups of patients with irritable bowel syndrome

(2011) Wolfgang Kruis et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

The RpoS-Mediated General Stress Response inEscherichia coli

(2010) Aurelia Battesti et al.   Annual Review of Microbiology

Treatment of colitis with a commensal gut bacterium engineered to secrete human tgf-β1 under the control of dietary xylan

(2010) Zaed Z.R. Hamady et al.   INFLAMMATORY BOWEL DISEASES

Translational Regulation of Gene Expression by an Anaerobically Induced Small Non-coding RNA in Escherichia coli

(2010) Anders Boysen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ArgR is an essential local transcriptional regulator of the arcABC operon in Streptococcus suis and is crucial for biological fitness in an acidic environment

(2010) M. Fulde et al.   MICROBIOLOGY-SGM

Reprogramming of anaerobic metabolism by the FnrS small RNA

(2010) Sylvain Durand et al.   MOLECULAR MICROBIOLOGY

Rifaximin Treatment in Hepatic Encephalopathy

(2010) Nathan M. Bass et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acid stress response in Escherichia coli: mechanism of regulation of gadA transcription by RcsB and GadE

(2010) Marie-Pierre Castanié-Cornet et al.   NUCLEIC ACIDS RESEARCH

Experimental models of hepatic encephalopathy: ISHEN guidelines

(2009) Roger F. Butterworth et al.   LIVER INTERNATIONAL

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Mechanism of arginine regulation of acetylglutamate synthase, the first enzyme of arginine synthesis

(2008) Enea Sancho-Vaello et al.   FEBS LETTERS

Interorgan ammonia trafficking in liver disease

(2008) Steven W. M. Olde Damink et al.   METABOLIC BRAIN DISEASE