Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

Microbiome therapeutics — Advances and challenges

(2016) Mark Mimee et al.   ADVANCED DRUG DELIVERY REVIEWS

Genetic and Metabolic Signals during Acute Enteric Bacterial Infection Alter the Microbiota and Drive Progression to Chronic Inflammatory Disease

(2016) Karishma Kamdar et al.   Cell Host & Microbe

A Multihit Model

(2015) Lydia M. Keubler et al.   INFLAMMATORY BOWEL DISEASES

Quantifying cellular capacity identifies gene expression designs with reduced burden

(2015) Francesca Ceroni et al.   NATURE METHODS

A distributed cell division counter reveals growth dynamics in the gut microbiota

(2015) Cameron Myhrvold et al.   Nature Communications

Programming a Human Commensal Bacterium, Bacteroides thetaiotaomicron, to Sense and Respond to Stimuli in the Murine Gut Microbiota

(2015) Mark Mimee et al.   Cell Systems

Inexpensive Multiplexed Library Preparation for Megabase-Sized Genomes

(2015) Michael Baym et al.   PLoS One

Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission

(2014) Michelle G Rooks et al.   ISME Journal

Permanent genetic memory with >1-byte capacity

(2014) Lei Yang et al.   NATURE METHODS

Programmable bacteria detect and record an environmental signal in the mammalian gut

(2014) Jonathan W. Kotula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomically encoded analog memory with precise in vivo DNA writing in living cell populations

(2014) F. Farzadfard et al.   SCIENCE

The dynamics of gut-associated microbial communities during inflammation

(2013) Sebastian E Winter et al.   EMBO REPORTS

Tetrathionate stimulated growth ofCampylobacter jejuniidentifies a new type of bi-functional tetrathionate reductase (TsdA) that is widely distributed in bacteria

(2013) Yang-Wei Liu et al.   MOLECULAR MICROBIOLOGY

Using Synthetic Biological Parts and Microbioreactors to Explore the Protein Expression Characteristics of Escherichia coli

(2013) Thomas E. Gorochowski et al.   ACS Synthetic Biology

Visualization of Evolutionary Stability Dynamics and Competitive Fitness of Escherichia coli Engineered with Randomized Multigene Circuits

(2013) Sean C. Sleight et al.   ACS Synthetic Biology

Fecal Lipocalin 2, a Sensitive and Broadly Dynamic Non-Invasive Biomarker for Intestinal Inflammation

(2012) Benoit Chassaing et al.   PLoS One

Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing

(2012) H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered E. coli That Detect and Respond to Gut Inflammation through Nitric Oxide Sensing

(2012) Eric J. Archer et al.   ACS Synthetic Biology

Genetic Circuit Performance under Conditions Relevant for Industrial Bioreactors

(2012) Felix Moser et al.   ACS Synthetic Biology

Gut inflammation provides a respiratory electron acceptor for Salmonella

(2010) Sebastian E. Winter et al.   NATURE

Designing and engineering evolutionary robust genetic circuits

(2010) Sean C Sleight et al.   Journal of Biological Engineering

Strain and model dependent differences in inflammatory cell recruitment in mice

(2008) J. L. Hoover-Plow et al.   INFLAMMATION RESEARCH