Next-generation probiotics: the spectrum from probiotics to live biotherapeutics

Emerging evidence of the role of gut microbiota in the development of allergic diseases

(2016) Kotryna Simonyte Sjödin et al.   Current Opinion in Allergy and Clinical Immunology

Safety assessment of the Clostridium butyricum MIYAIRI 588® probiotic strain including evaluation of antimicrobial sensitivity and presence of Clostridium toxin genes in vitro and teratogenicity in vivo

(2016) K Isa et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Faecalibacterium prausnitzii subspecies–level dysbiosis in the human gut microbiome underlying atopic dermatitis

(2016) Han Song et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Modulating the human microbiome with live biotherapeutic products: intellectual property landscape

(2016) Xiaowei Sun et al.   NATURE REVIEWS DRUG DISCOVERY

Effect of probiotics on postoperative quality of gastric bypass surgeries: a prospective randomized trial

(2016) Jung-Chien Chen et al.   Surgery for Obesity and Related Diseases

A novel strain of Bacteroides fragilis enhances phagocytosis and polarises M1 macrophages

(2016) Huimin Deng et al.   Scientific Reports

Impact of oral consumption of heat-treated Bacteroides xylanisolvens DSM 23964 on the level of natural TFα-specific antibodies in human adults

(2016) P. Ulsemer et al.   Beneficial Microbes

Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses

(2016) Oriana Rossi et al.   Scientific Reports

The effect of Clostridium butyricum MIYAIRI on the prevention of pouchitis and alteration of the microbiota profile in patients with ulcerative colitis

(2015) Asuka Yasueda et al.   SURGERY TODAY

Induction of Peroxisomes by Butyrate-Producing Probiotics

(2015) Huachun Weng et al.   PLoS One

From Stool Transplants to Next-Generation Microbiota Therapeutics

(2014) Elaine O. Petrof et al.   GASTROENTEROLOGY

Recombinant Lactococcus lactis can make the difference in antigen-specific immune tolerance induction, the Type 1 Diabetes case

(2014) Sofie Robert et al.   Microbial Cell Factories

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

Faecalibacterium prausnitzii Inhibits Interleukin-17 to Ameliorate Colorectal Colitis in Rats

(2014) Mingming Zhang et al.   PLoS One

Specific humoral immune response to the Thomsen-Friedenreich tumor antigen (CD176) in mice after vaccination with the commensal bacterium Bacteroides ovatus D-6

(2013) Philippe Ulsemer et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Clostridium Butyricum MIYAIRI 588 Improves High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats

(2013) Makoto Seo et al.   DIGESTIVE DISEASES AND SCIENCES

Substrate Cleavage Profiling Suggests a Distinct Function ofBacteroides fragilisMetalloproteinases (Fragilysin and Metalloproteinase II) at the Microbiome-Inflammation-Cancer Interface

(2013) Sergey A. Shiryaev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Medicines from microbiota

(2013) Bernat Olle   NATURE BIOTECHNOLOGY

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

IgA production in the large intestine is modulated by a different mechanism than in the small intestine: Bacteroides acidifaciens promotes IgA production in the large intestine by inducing germinal center formation and increasing the number of IgA+ B cells

(2012) Tsutomu Yanagibashi et al.   IMMUNOBIOLOGY

Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis

(2012) J.-P. Motta et al.   Science Translational Medicine

Preliminary Safety Evaluation of a New Bacteroides xylanisolvens Isolate

(2011) Philippe Ulsemer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Inhibition of the cytotoxic effect of Clostridium difficile in vitro by Clostridium butyricum MIYAIRI 588 strain

(2011) T. D. H. Woo et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Treatment of colitis with a commensal gut bacterium engineered to secrete human tgf-β1 under the control of dietary xylan

(2010) Zaed Z.R. Hamady et al.   INFLAMMATORY BOWEL DISEASES

AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis

(2010) Silvia Caluwaerts et al.   ORAL ONCOLOGY

Sequence analysis of a bacteriocinogenic plasmid of Clostridium butyricum and expression of the bacteriocin gene in Escherichia coli

(2009) Shusuke Nakanishi et al.   ANAEROBE

Xylan-regulated delivery of human keratinocyte growth factor-2 to the inflamed colon by the human anaerobic commensal bacterium Bacteroides ovatus

(2009) Z. Z R Hamady et al.   GUT

Effects of Active Egg White Product/ Clostridium butyricum Miyairi 588 Additive on Peripheral Leukocyte Populations in Periparturient Dairy Cows

(2008) Masayuki KOHIRUIMAKI et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Identification and use of the putative Bacteroides ovatus xylanase promoter for the inducible production of recombinant human proteins

(2008) Z. Z. R. Hamady et al.   MICROBIOLOGY-SGM

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA