The bright and the dark sides of activin in wound healing and cancer

Langerhans Cells Facilitate Epithelial DNA Damage and Squamous Cell Carcinoma

(2012) B. G. Modi et al.   SCIENCE

Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers

(2011) E. Sierra-Filardi et al.   BLOOD

Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer

(2011) H Kaneda et al.   BRITISH JOURNAL OF CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Generation of a Specific Activin Antagonist by Modification of the Activin A Propeptide

(2011) Yogeshwar Makanji et al.   ENDOCRINOLOGY

Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands

(2011) Craig A. Harrison et al.   GROWTH FACTORS

Activins and activin antagonists in the prostate and prostate cancer

(2011) Elspeth Gold et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Activin B Promotes Epithelial Wound Healing In Vivo through RhoA-JNK Signaling Pathway

(2011) Min Zhang et al.   PLoS One

Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response

(2011) Maria Antsiferova et al.   Nature Communications

Overexpression of Activin A in Oral Squamous Cell Carcinoma: Association with Poor Prognosis and Tumor Progression

(2010) Kai-Ping Chang et al.   ANNALS OF SURGICAL ONCOLOGY

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

(2010) Xiaolan Zhou et al.   CELL

Effects of activin A on IgE synthesis and cytokine production by human peripheral mononuclear cells

(2010) N. YAMASHITA et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Tumors as Organs: Complex Tissues that Interface with the Entire Organism

(2010) Mikala Egeblad et al.   DEVELOPMENTAL CELL

Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo

(2010) Andrew D Chantry et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease

(2010) S. Vallet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia

(2009) Margaret E. Benny Klimek et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activin-A attenuates several human natural killer cell functions

(2009) N. C. Robson et al.   BLOOD

Activin A induces dendritic cell migration through the polarized release of CXC chemokine ligands 12 and 14

(2009) L. Salogni et al.   BLOOD

Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease

(2009) Maria Semitekolou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activin A Promotes the TGF- -Induced Conversion of CD4+CD25- T Cells into Foxp3+ Induced Regulatory T Cells

(2009) S. Huber et al.   JOURNAL OF IMMUNOLOGY

Key Role for Activin B in Cellular Transformation after Loss of the von Hippel-Lindau Tumor Suppressor

(2009) I. Wacker et al.   MOLECULAR AND CELLULAR BIOLOGY

Follistatin Suppresses the Production of Experimental Multiple-Organ Metastasis by Small Cell Lung Cancer Cells in Natural Killer Cell-Depleted SCID Mice

(2008) H. Ogino et al.   CLINICAL CANCER RESEARCH

Signal Transduction Pathway through Activin Receptors as a Therapeutic Target of Musculoskeletal Diseases and Cancer

(2008) Kunihiro TSUCHIDA et al.   ENDOCRINE JOURNAL

Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells

(2008) Rachael A. Clark et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair

(2008) Maria Antsiferova et al.   LABORATORY INVESTIGATION

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

(2008) Qizhi Tang et al.   NATURE IMMUNOLOGY

Cancer as an overhealing wound: an old hypothesis revisited

(2008) Matthias Schäfer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activin A Induces Langerhans Cell Differentiation In Vitro and in Human Skin Explants

(2008) Tiziana Musso et al.   PLoS One