The Genetics of Pulmonary Arterial Hypertension in the Post-BMPR2 Era

Design of the REVEAL Registry for US Patients With Pulmonary Arterial Hypertension

(2012) Michael D. McGoon et al.   MAYO CLINIC PROCEEDINGS

Survival of Chinese Patients With Pulmonary Arterial Hypertension in the Modern Treatment Era

(2011) Rui Zhang et al.   CHEST

BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension

(2010) M. Talati et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Clinical Outcomes of Pulmonary Arterial Hypertension in Patients Carrying anACVRL1(ALK1) Mutation

(2010) Barbara Girerd et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Angiotensin-Converting Enzyme 2/Angiogenesis-(1–7)/Mas Axis Confers Cardiopulmonary Protection against Lung Fibrosis and Pulmonary Hypertension

(2010) Vinayak Shenoy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Somatic Chromosome Abnormalities in the Lungs of Patients with Pulmonary Arterial Hypertension

(2010) Micheala A. Aldred et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Association of a KCNA5 gene polymorphism with systemic sclerosis-associated pulmonary arterial hypertension in the European Caucasian population

(2010) J. Wipff et al.   ARTHRITIS AND RHEUMATISM

Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and acute pulmonary hypertension post cardiopulmonary bypass in children with congenital cardiac diseases

(2010) Tsvetomir Loukanov et al.   CARDIOLOGY IN THE YOUNG

Long-term Effects of Epoprostenol on the Pulmonary Vasculature in Idiopathic Pulmonary Arterial Hypertension

(2010) Stuart Rich et al.   CHEST

The Changing Picture of Patients With Pulmonary Arterial Hypertension in the United States

(2010) Adaani E. Frost et al.   CHEST

Predicting Survival in Pulmonary Arterial Hypertension

(2010) Raymond L. Benza et al.   CIRCULATION

Survival in Patients With Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension in the Modern Management Era

(2010) Marc Humbert et al.   CIRCULATION

Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension

(2010) M. Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil

(2010) K. T. B. Mouchaers et al.   EUROPEAN RESPIRATORY JOURNAL

Estrogens and Development of Pulmonary Hypertension: Interaction of Estradiol Metabolism and Pulmonary Vascular Disease

(2010) Stevan P Tofovic   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Synergistic Therapeutic Effects of 2-Methoxyestradiol With Either Sildenafil or Bosentan on Amelioration of Monocrotaline-induced Pulmonary Hypertension and Vascular Remodeling

(2010) Stevan P Tofovic et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Role of apoptosis in pulmonary hypertension: From experimental models to clinical trials

(2010) Paul Jurasz et al.   PHARMACOLOGY & THERAPEUTICS

Pulmonary vascular pressure profiles in broilers selected for susceptibility to pulmonary hypertension syndrome: Age and sex comparisons

(2010) R. F. Wideman et al.   POULTRY SCIENCE

Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

(2009) Kurt R. Stenmark et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Genetic Risk Factors for Portopulmonary Hypertension in Patients with Advanced Liver Disease

(2009) Kari E. Roberts et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension

(2009) Anderson J. Ferreira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

GDF5 and BMP2 inhibit apoptosis via activation of BMPR2 and subsequent stabilization of XIAP

(2009) Zhipei Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Serotonin Transporter Polymorphisms in Patients With Portopulmonary Hypertension

(2009) Kari E. Roberts et al.   CHEST

Pulmonary Arterial Hypertension

(2009) David B. Badesch et al.   CHEST

Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females

(2009) E. D. Austin et al.   EUROPEAN RESPIRATORY JOURNAL

Defective pulmonary vascular remodeling in Smad8 mutant mice

(2009) Z. Huang et al.   HUMAN MOLECULAR GENETICS

Penetrance of pulmonary arterial hypertension is modulated by the expression of normalBMPR2allele

(2009) Rizwan Hamid et al.   HUMAN MUTATION

Polymorphism in the Angiotensin II Type 1 Receptor (AGTR1) is Associated With Age at Diagnosis in Pulmonary Arterial Hypertension

(2009) Wendy K. Chung et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension

(2009) M Shintani et al.   JOURNAL OF MEDICAL GENETICS

Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis

(2009) Eric Blasko et al.   JOURNAL OF NEUROIMMUNOLOGY

ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension

(2009) Vallerie V. McLaughlin et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Development and Pathology of Pulmonary Hypertension

(2009) Rubin M. Tuder et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetics and Genomics of Pulmonary Arterial Hypertension

(2009) Rajiv D. Machado et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diagnosis and Assessment of Pulmonary Arterial Hypertension

(2009) David B. Badesch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Updated Clinical Classification of Pulmonary Hypertension

(2009) Gérald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetics of Pulmonary Arterial Hypertension

(2009) Eric Austin et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

(2008) James West et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Clinical Outcomes of Pulmonary Arterial Hypertension in Carriers ofBMPR2Mutation

(2008) Benjamin Sztrymf et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Gene expression in BMPR2 mutation carriers with and without evidence of Pulmonary Arterial Hypertension suggests pathways relevant to disease penetrance

(2008) James West et al.   BMC Medical Genomics

Genetic Ablation of the Bmpr2 Gene in Pulmonary Endothelium Is Sufficient to Predispose to Pulmonary Arterial Hypertension

(2008) Kwon-Ho Hong et al.   CIRCULATION

Synergistic heterozygosity for TGFβ1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension

(2008) John A Phillips et al.   GENETICS IN MEDICINE

What Patients and Their Relatives Think About Testing for BMPR2

(2008) Diana L. Jones et al.   Journal of Genetic Counseling

Clinical Implications of Determining BMPR2 Mutation Status in a Large Cohort of Children and Adults With Pulmonary Arterial Hypertension

(2008) Erika B. Rosenzweig et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION