Health disparities: Intracellular consequences of social determinants of health

Cysteine Toxicity Drives Age-Related Mitochondrial Decline by Altering Iron Homeostasis

(2020) Casey E. Hughes et al.   CELL

Implications of Oxidative Stress and Cellular Senescence in Age-Related Thymus Involution

(2020) Alexandra Barbouti et al.   Oxidative Medicine and Cellular Longevity

Inter-organelle Communication in the Pathogenesis of Mitochondrial Dysfunction and Insulin Resistance

(2020) Stacey N. Keenan et al.   Current Diabetes Reports

The Role of Reactive Oxygen Species in the Life Cycle of the Mitochondrion

(2020) Paola Venditti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Managing Asthma during Coronavirus Disease-2019: An Example for Other Chronic Conditions in Children and Adolescents

(2020) Elissa M. Abrams et al.   JOURNAL OF PEDIATRICS

Hospitalization and Mortality among Black Patients and White Patients with Covid-19

(2020) Eboni G. Price-Haywood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study

(2020) Christopher M Petrilli et al.   BMJ-British Medical Journal

The fire this time: The stress of racism, inflammation and COVID-19

(2020) Olusola Ajilore et al.   BRAIN BEHAVIOR AND IMMUNITY

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

(2020) Ekaterina V. Vinogradova et al.   CELL

The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

(2020) Parimal Samir et al.   Frontiers in Cellular and Infection Microbiology

Childhood Physical Neglect Is Associated With Exaggerated Systemic and Intracellular Inflammatory Responses to Repeated Psychosocial Stress in Adulthood

(2020) Hannah M. C. Schreier et al.   Frontiers in Psychiatry

A Cellular Mechanism to Detect and Alleviate Reductive Stress

(2020) Andrew G. Manford et al.   CELL

Sirtuins and Type 2 Diabetes: Role in Inflammation, Oxidative Stress, and Mitochondrial Function

(2019) Munehiro Kitada et al.   Frontiers in Endocrinology

Multi-cohort study identifies social determinants of systemic inflammation over the life course

(2019) Eloïse Berger et al.   Nature Communications

Two Distinct Immune Pathways Linking Social Relationships with Health

(2019) Carrianne J. Leschak et al.   PSYCHOSOMATIC MEDICINE

Organelle crosstalk in the kidney

(2019) Tsuyoshi Inoue et al.   KIDNEY INTERNATIONAL

The cationic (calcium and lead) and enzyme conundrum

(2019) Jane Kasten-Jolly et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Mitochondrial Dysfunction and Aging: Insights from the Analysis of Extracellular Vesicles

(2019) Anna Picca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Racial disparities in preterm birth in USA: a biosensor of physical and social environmental exposures

(2019) Heather H Burris et al.   ARCHIVES OF DISEASE IN CHILDHOOD

The Impact of Environmental Chronic and Toxic Stress on Asthma

(2019) Maggie Barnthouse et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death

(2019) Daniel N. Meijles et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk

(2019) Anthony S. Zannas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Closing the door on social determinants of health and asthma disparities: Not so fast

(2019) Elizabeth C. Matsui et al.   Journal of Allergy and Clinical Immunology-In Practice

Metabolic Responses to Reductive Stress

(2019) Wusheng Xiao et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of different SIRT1-mediated signaling pathways in toxic injury

(2019) Zhihua Ren et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Proinsulin misfolding is an early event in the progression to type 2 diabetes

(2019) Anoop Arunagiri et al.   eLife

Mitochondrial Homeostasis and Cellular Senescence

(2019) Panagiotis V.S. Vasileiou et al.   Cells

Metabolic implications of organelle–mitochondria communication

(2019) Isabel Gordaliza‐Alaguero et al.   EMBO REPORTS

Measures of Racism, Sexism, Heterosexism, and Gender Binarism for Health Equity Research: From Structural Injustice to Embodied Harm—an Ecosocial Analysis

(2019) Nancy Krieger   Annual Review of Public Health

Resolving the topological enigma in Ca2+-signaling by cyclic ADP-ribose and NAADP

(2019) Hon Cheung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)

(2019) R. K. Subbarao Malireddi et al.   Frontiers in Cellular and Infection Microbiology

Mitochondria, Telomeres and Telomerase Subunits

(2019) Qian Zheng et al.   Frontiers in Cell and Developmental Biology

Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses

(2019) Yiliang Chen et al.   CIRCULATION RESEARCH

Joint impact of phthalate exposure and stressful life events in pregnancy on preterm birth

(2019) Kelly K. Ferguson et al.   ENVIRONMENT INTERNATIONAL

Interacting organelles

(2018) Sarah Cohen et al.   CURRENT OPINION IN CELL BIOLOGY

Altered Extracellular Vesicle Concentration, Cargo and Function in Diabetes Mellitus

(2018) David W. Freeman et al.   DIABETES

Impact of oxidative stress on telomere biology

(2018) Wareed Ahmed et al.   DIFFERENTIATION

Age and immunity: What is “immunosenescence”?

(2018) Graham Pawelec   EXPERIMENTAL GERONTOLOGY

Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives

(2018) Darren J. Baker et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms and functions of cellular senescence

(2018) Nicolás Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin 17A exacerbates ER-stress-mediated inflammation of macrophages following ICH

(2018) Zhao Yang et al.   MOLECULAR IMMUNOLOGY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Developmental Lead Exposure and Prenatal Stress Result in Sex-Specific Reprograming of Adult Stress Physiology and Epigenetic Profiles in Brain

(2018) Marissa Sobolewski et al.   TOXICOLOGICAL SCIENCES

Associations between Food Security Status and Dietary Inflammatory Potential within Lower-Income Adults from the United States National Health and Nutrition Examination Survey, Cycles 2007 to 2014

(2018) Rachel S. Bergmans et al.   Journal of the Academy of Nutrition and Dietetics

Influence of Inflammation in the Process of T Lymphocyte Differentiation: Proliferative, Metabolic, and Oxidative Changes

(2018) Marco A. Moro-García et al.   Frontiers in Immunology

Investigation of association between environmental and socioeconomic factors and preterm birth in California

(2018) Hongtai Huang et al.   ENVIRONMENT INTERNATIONAL

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

(2018) Luigi Ferrucci et al.   Nature Reviews Cardiology

Impaired immune surveillance accelerates accumulation of senescent cells and aging

(2018) Yossi Ovadya et al.   Nature Communications

Stress and immunosenescence: The role of telomerase

(2018) Karin de Punder et al.   PSYCHONEUROENDOCRINOLOGY

Prenatal famine exposure, adulthood obesity patterns and risk of type 2 diabetes

(2017) Ruogu Meng et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

From Infections to Anthropogenic Inflicted Pathologies: Involvement of Immune Balance

(2017) Florence Lee et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model

(2017) Rebecca T Emeny et al.   NEUROPSYCHOPHARMACOLOGY

Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress

(2017) Gireedhar Venkatachalam et al.   NUCLEIC ACIDS RESEARCH

Role of oxidative stress and antioxidants in daily nutrition and human health

(2017) Geir Bjørklund et al.   NUTRITION

Cytokine storm and sepsis disease pathogenesis

(2017) Benjamin G. Chousterman et al.   Seminars in Immunopathology

Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection

(2017) Marcia Bellon et al.   Viruses-Basel

The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells

(2017) Camille Loubiere et al.   Scientific Reports

Mitochondrial NAD+/NADH Redox State and Diabetic Cardiomyopathy

(2017) Jessica M. Berthiaume et al.   ANTIOXIDANTS & REDOX SIGNALING

Sensing of redox status by TRP channels

(2016) Nozomi Ogawa et al.   CELL CALCIUM

Environmental exposures and the development of systemic lupus erythematosus

(2016) Medha Barbhaiya et al.   CURRENT OPINION IN RHEUMATOLOGY

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Nicholas J Kassebaum et al.   LANCET

The role of oxidative and inflammatory stress and persistent viral infections in immunosenescence

(2016) Moisés Evandro Bauer et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Role of ROS and RNS Sources in Physiological and Pathological Conditions

(2016) Sergio Di Meo et al.   Oxidative Medicine and Cellular Longevity

Oxidative Homeostasis Regulates the Response to Reductive Endoplasmic Reticulum Stress through Translation Control

(2016) Shuvadeep Maity et al.   Cell Reports

The Role of Endoplasmic Reticulum Stress in Human Pathology

(2015) Scott A. Oakes et al.   Annual Review of Pathology-Mechanisms of Disease

NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes

(2015) Sorina Georgiana Boaru et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Analysis of septic biomarker patterns: prognostic value in predicting septic state

(2015) Cynthia J. Carlyn et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

NLRP3 at the interface of metabolism and inflammation

(2015) Moritz Haneklaus et al.   IMMUNOLOGICAL REVIEWS

Epigenetics: linking social and environmental exposures to preterm birth

(2015) Heather H. Burris et al.   PEDIATRIC RESEARCH

ENDOPLASMIC RETICULUM STRESS IN SEPSIS

(2015) Mohammad Moshahid Khan et al.   SHOCK

A physical/psychological and biological stress combine to enhance endoplasmic reticulum stress

(2015) Tapan Kumar Mondal et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inflammation and neuronal plasticity: a link between childhood trauma and depression pathogenesis

(2015) Annamaria Cattaneo et al.   Frontiers in Cellular Neuroscience

Impact of Air Pollutants on Oxidative Stress in Common Autophagy-Mediated Aging Diseases

(2015) Mohamed Numan et al.   International Journal of Environmental Research and Public Health

Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians

(2015) Yasumichi Arai et al.   EBioMedicine

NLRP3 Mediates NF-κB Activation and Cytokine Induction in Microbially Induced and Sterile Inflammation

(2015) Takeshi Kinoshita et al.   PLoS One

Rheostat Re-Wired: Alternative Hypotheses for the Control of Thioredoxin Reduction Potentials

(2015) Kathryn D. Bewley et al.   PLoS One

Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation

(2015) Prajwal Gurung et al.   Scientific Reports

Mitochondrial Biogenesis in Health and Disease. Molecular and Therapeutic Approaches

(2014) Fabian Sanchis-Gomar et al.   CURRENT PHARMACEUTICAL DESIGN

Early-Life Bisphenol A Exposure and Child Body Mass Index: A Prospective Cohort Study

(2014) Joseph M. Braun et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Psychological Stress in Children May Alter the Immune Response

(2014) E. Carlsson et al.   JOURNAL OF IMMUNOLOGY

Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development

(2014) H. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAD+ and sirtuins in aging and disease

(2014) Shin-ichiro Imai et al.   TRENDS IN CELL BIOLOGY

Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation

(2014) Huu B. Ngo et al.   Nature Communications

Human Social Genomics

(2014) Steven W. Cole   PLoS Genetics

Nanoparticles, Lung Injury, and the Role of Oxidant Stress

(2013) Amy K. Madl et al.   Annual Review of Physiology

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity

(2013) Michael K Skinner et al.   BMC Medicine

Oxidative stress and vascular inflammation in aging

(2013) Mariam El Assar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

(2013) Shankar S. Iyer et al.   IMMUNITY

Childhood maltreatment and obesity: systematic review and meta-analysis

(2013) A Danese et al.   MOLECULAR PSYCHIATRY

TRPM2 links oxidative stress to NLRP3 inflammasome activation

(2013) Zhenyu Zhong et al.   Nature Communications

The Incidence and Prevalence of Systemic Lupus Erythematosus, 2002-2004: The Georgia Lupus Registry

(2013) S. Sam Lim et al.   Arthritis & Rheumatology

Population-Based Incidence and Prevalence of Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program

(2013) Emily C. Somers et al.   Arthritis & Rheumatology

Environmental exposures: an underrecognized contribution to noncommunicable diseases

(2013) Rosana E. Norman et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Telomere length and cardiovascular aging

(2012) Frej Fyhrquist et al.   ANNALS OF MEDICINE

Redox Regulation of T-Cell Function: From Molecular Mechanisms to Significance in Human Health and Disease

(2012) Pravin Kesarwani et al.   ANTIOXIDANTS & REDOX SIGNALING

The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses

(2012) Masaaki Iwata et al.   BRAIN BEHAVIOR AND IMMUNITY

Strategies to Improve the Functions and Redox State of the Immune System in Aged Subjects

(2012) Monica De la Fuente et al.   CURRENT PHARMACEUTICAL DESIGN

Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development

(2012) Heon Park et al.   IMMUNITY

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

The exposome: from concept to utility

(2012) Christopher Paul Wild   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Septins: the fourth component of the cytoskeleton

(2012) Serge Mostowy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Changes in primary lymphoid organs with aging

(2012) Ivan K. Chinn et al.   SEMINARS IN IMMUNOLOGY

The inflammatory response in sepsis

(2012) Markus Bosmann et al.   TRENDS IN IMMUNOLOGY

Early life socioeconomic adversity is associated in adult life with chronic inflammation, carotid atherosclerosis, poorer lung function and decreased cognitive performance: a cross-sectional, population-based study

(2011) Chris J Packard et al.   BMC PUBLIC HEALTH

Prenatal Concentrations of Polychlorinated Biphenyls, DDE, and DDT and Overweight in Children: A Prospective Birth Cohort Study

(2011) Damaskini Valvi et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mitochondrial DNA and inflammatory diseases

(2011) Germaine Escames et al.   HUMAN GENETICS

Inflammation, Oxidative Stress, and Obesity

(2011) Alba Fernández-Sánchez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sirtuins, Aging, and Medicine

(2011) Leonard Guarente   NEW ENGLAND JOURNAL OF MEDICINE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Innate and adaptive immunosenescence

(2010) Shradha Agarwal et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

The IP3 receptor–mitochondria connection in apoptosis and autophagy

(2010) Jean-Paul Decuypere et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

AMPK-independent induction of autophagy by cytosolic Ca2+ increase

(2010) Antje Grotemeier et al.   CELLULAR SIGNALLING

Systemic Inflammatory Response Syndrome and Compensatory Anti-Inflammatory Response Syndrome in Sepsis

(2010) Tom van der Poll et al.   Journal of Innate Immunity

Childhood Adversities Are Associated with Shorter Telomere Length at Adult Age both in Individuals with an Anxiety Disorder and Controls

(2010) Laura Kananen et al.   PLoS One

Redox Control of Asthma: Molecular Mechanisms and Therapeutic Opportunities

(2009) Suzy A.A. Comhair et al.   ANTIOXIDANTS & REDOX SIGNALING

Adverse Childhood Experiences and Adult Risk Factors for Age-Related Disease

(2009) Andrea Danese et al.   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

Telomerase, mitochondria and oxidative stress

(2009) Gabriele Saretzki   EXPERIMENTAL GERONTOLOGY

Early trauma and adult obesity: Is psychological dysfunction the mediating mechanism?

(2009) Alberto D'Argenio et al.   PHYSIOLOGY & BEHAVIOR

Intrauterine Exposure to Environmental Pollutants and Body Mass Index during the First 3 Years of Life

(2008) Stijn L. Verhulst et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

(2008) Shinichiro Yamamoto et al.   NATURE MEDICINE

Effect of In Utero and Early-Life Conditions on Adult Health and Disease

(2008) Peter D. Gluckman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alterations in glucocorticoid negative feedback following maternal Pb, prenatal stress and the combination: A potential biological unifying mechanism for their corresponding disease profiles

(2008) A. Rossi-George et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY