Sirtuins and Type 2 Diabetes: Role in Inflammation, Oxidative Stress, and Mitochondrial Function
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Title
Sirtuins and Type 2 Diabetes: Role in Inflammation, Oxidative Stress, and Mitochondrial Function
Authors
Keywords
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Journal
Frontiers in Endocrinology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-03-27
DOI
10.3389/fendo.2019.00187
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Note: Only part of the references are listed.- The Role of Sirtuins in Antioxidant and Redox Signaling
- (2018) Chandra K. Singh et al. ANTIOXIDANTS & REDOX SIGNALING
- Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty rats
- (2018) Yoshio Ogura et al. REDOX REPORT
- SIRT5 regulates pancreatic β‑cell proliferation and insulin secretion in type 2 diabetes
- (2018) Yongmei Ma et al. Experimental and Therapeutic Medicine
- The Role of Sirt6 in Obesity and Diabetes
- (2018) Jiangying Kuang et al. Frontiers in Physiology
- Sirtuin 5 overexpression attenuates glucolipotoxicity-induced pancreatic β cells apoptosis and dysfunction
- (2018) Yue Wang et al. EXPERIMENTAL CELL RESEARCH
- The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes
- (2017) Vera Lemos et al. HUMAN MOLECULAR GENETICS
- SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2
- (2016) Huize Pan et al. CELL RESEARCH
- SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense
- (2016) Lisha Zhou et al. EMBO REPORTS
- SIRT6 protects against palmitate-induced pancreatic β-cell dysfunction and apoptosis
- (2016) Xiwen Xiong et al. JOURNAL OF ENDOCRINOLOGY
- SIRT6 deacetylates PKM2 to suppress its nuclear localization and oncogenic functions
- (2016) Abhishek Bhardwaj et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of sirtuin 6 accelerates endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient mice
- (2016) Zhiping Liu et al. Translational Research
- Islet β-cell failure in type 2 diabetes – Within the network of toxic lipids
- (2015) Justyna Janikiewicz et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells
- (2015) Xiwen Xiong et al. DIABETOLOGIA
- SIRT3 regulates progression and development of diseases of aging
- (2015) Eoin McDonnell et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism
- (2015) Pedro Gomes et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction
- (2015) Min Kim et al. PLoS One
- SIRT4 Suppresses Inflammatory Responses in Human Umbilical Vein Endothelial Cells
- (2014) Yu Tao et al. Cardiovascular Toxicology
- Sirtuin 6 Expression and Inflammatory Activity in Diabetic Atherosclerotic Plaques: Effects of Incretin Treatment
- (2014) Maria Luisa Balestrieri et al. DIABETES
- Regulation of G6PD acetylation by KAT9/SIRT2 modulates NADPH homeostasis and cell survival during oxidative stress
- (2014) Y.-P. Wang et al. EMBO JOURNAL
- SIRT2 Deficiency Modulates Macrophage Polarization and Susceptibility to Experimental Colitis
- (2014) Giuseppe Lo Sasso et al. PLoS One
- Sirt2 suppresses inflammatory responses in collagen-induced arthritis
- (2013) Jiangtao Lin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Sirtuins as Possible Drug Targets in Type 2 Diabetes
- (2013) Munehiro Kitada et al. CURRENT DRUG TARGETS
- Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients
- (2013) P. W. Caton et al. DIABETOLOGIA
- The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation
- (2013) Teresa Faria Pais et al. EMBO JOURNAL
- Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization
- (2013) Lei Lv et al. MOLECULAR CELL
- SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential
- (2013) Munehiro Kitada et al. Diabetes & Metabolism Journal
- SIRT1 inactivation induces inflammation through the dysregulation of autophagy in human THP-1 cells
- (2012) Ai Takeda-Watanabe et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dietary obesity-associated Hif1 activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system
- (2012) J. Krishnan et al. GENES & DEVELOPMENT
- Anti-Inflammatory Properties of Sirtuin 6 in Human Umbilical Vein Endothelial Cells
- (2012) Martha Lappas MEDIATORS OF INFLAMMATION
- The sirtuin SIRT6 regulates lifespan in male mice
- (2012) Yariv Kanfi et al. NATURE
- Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
- (2011) Eriko Michishita et al. CELL CYCLE
- SirT1 Regulates Adipose Tissue Inflammation
- (2011) M. P. Gillum et al. DIABETES
- Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1
- (2011) Sara Fröjdö et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Resveratrol and health - A comprehensive review of human clinical trials
- (2011) James M. Smoliga et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Sirtuins, Aging, and Medicine
- (2011) Leonard Guarente NEW ENGLAND JOURNAL OF MEDICINE
- Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity
- (2011) Lydia W. S. Finley et al. PLoS One
- Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
- (2011) E. Jing et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macrophages, Inflammation, and Insulin Resistance
- (2010) Jerrold M. Olefsky et al. Annual Review of Physiology
- Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
- (2010) Shinichi Someya et al. CELL
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- (2010) Xiaolei Qiu et al. Cell Metabolism
- Downregulation of the Longevity-Associated Protein Sirtuin 1 in Insulin Resistance and Metabolic Syndrome: Potential Biochemical Mechanisms
- (2010) S. V. de Kreutzenberg et al. DIABETES
- JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction
- (2010) Giovanni Solinas et al. FASEB JOURNAL
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- (2010) K. M. Rothgiesser et al. JOURNAL OF CELL SCIENCE
- Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress
- (2010) T. T. Schug et al. MOLECULAR AND CELLULAR BIOLOGY
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- (2010) Masato Iwabu et al. NATURE
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- (2010) Matthew D. Hirschey et al. NATURE
- Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity
- (2010) B. Schwer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extending Healthy Life Span--From Yeast to Humans
- (2010) L. Fontana et al. SCIENCE
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- (2009) Yariv Kanfi et al. AGING CELL
- SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
- (2009) Takeshi Yoshizaki et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
- (2009) Tiara L.A. Kawahara et al. CELL
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- (2009) Tara L. Archuleta et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2008) T. Yoshizaki et al. MOLECULAR AND CELLULAR BIOLOGY
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- (2008) Gino Boily et al. PLoS One
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