- Home
- Publications
- Publication Search
- Publication Details
Title
Sirtuins, Aging, and Medicine
Authors
Keywords
-
Journal
NEW ENGLAND JOURNAL OF MEDICINE
Volume 364, Issue 23, Pages 2235-2244
Publisher
New England Journal of Medicine (NEJM/MMS)
Online
2011-06-09
DOI
10.1056/nejmra1100831
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Liver Steatosis and Increased ChREBP Expression in Mice Carrying a Liver Specific SIRT1 Null Mutation under a Normal Feeding Condition
- (2012) Rui-Hong Wang et al. International Journal of Biological Sciences
- SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization
- (2011) Lydia W.S. Finley et al. CANCER CELL
- Sirtuins at a glance
- (2011) T. Nakagawa et al. JOURNAL OF CELL SCIENCE
- Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction
- (2011) William C. Hallows et al. MOLECULAR CELL
- SIRT1 inhibits angiotensin II-induced vascular smooth muscle cell hypertrophy
- (2010) L. Li et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Aging and disease: connections to sirtuins
- (2010) Gizem Donmez et al. AGING CELL
- AMPK and SIRT1: a long-standing partnership?
- (2010) Neil B. Ruderman et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1
- (2010) Masahito Ogura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress
- (2010) Hyun-Seok Kim et al. CANCER CELL
- Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
- (2010) Shinichi Someya et al. CELL
- RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10
- (2010) Gizem Donmez et al. CELL
- Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
- (2010) Xiaolei Qiu et al. Cell Metabolism
- SIRT1 Deacetylase in POMC Neurons Is Required for Homeostatic Defenses against Diet-Induced Obesity
- (2010) Giorgio Ramadori et al. Cell Metabolism
- Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
- (2010) A. K. Walker et al. GENES & DEVELOPMENT
- Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma
- (2010) Ho Lee et al. HUMAN PATHOLOGY
- Kidney-specific Overexpression of Sirt1 Protects against Acute Kidney Injury by Retaining Peroxisome Function
- (2010) Kazuhiro Hasegawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism
- (2010) Bhaskar Ponugoti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells
- (2010) Nargis Nasrin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT1 Activation by Small Molecules
- (2010) Han Dai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
- (2010) Michelle Pacholec et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice
- (2010) Carlos Escande et al. JOURNAL OF CLINICAL INVESTIGATION
- Sirt1 activation protects the mouse renal medulla from oxidative injury
- (2010) Wenjuan He et al. JOURNAL OF CLINICAL INVESTIGATION
- Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
- (2010) Shinji Kume et al. JOURNAL OF CLINICAL INVESTIGATION
- SIRT1 Is Essential for Normal Cognitive Function and Synaptic Plasticity
- (2010) S. Michan et al. JOURNAL OF NEUROSCIENCE
- SIRT1 Promotes the Central Adaptive Response to Diet Restriction through Activation of the Dorsomedial and Lateral Nuclei of the Hypothalamus
- (2010) A. Satoh et al. JOURNAL OF NEUROSCIENCE
- Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress
- (2010) Randa Tao et al. MOLECULAR CELL
- A novel pathway regulates memory and plasticity via SIRT1 and miR-134
- (2010) Jun Gao et al. NATURE
- SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
- (2010) Matthew D. Hirschey et al. NATURE
- Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
- (2010) Sang-Won Min et al. NEURON
- 3-Ketoacyl thiolase delays aging of Caenorhabditis elegans and is required for lifespan extension mediated by sir-2.1
- (2010) A. Berdichevsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
- (2010) Daniel Herranz et al. Nature Communications
- Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
- (2009) Jesse J Smith et al. BMC Systems Biology
- SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle
- (2009) Takashi Nakagawa et al. CELL
- SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
- (2009) Tiara L.A. Kawahara et al. CELL
- FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States
- (2009) Jongsook Kim Kemper et al. Cell Metabolism
- Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation
- (2009) Aparna Purushotham et al. Cell Metabolism
- Disruption of the Ang II type 1 receptor promotes longevity in mice
- (2009) Ariela Benigni et al. JOURNAL OF CLINICAL INVESTIGATION
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
- (2009) G Boily et al. ONCOGENE
- SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells
- (2008) Ryohei Miyazaki et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Cilostazol Inhibits Oxidative Stress–Induced Premature Senescence Via Upregulation of Sirt1 in Human Endothelial Cells
- (2008) Hidetaka Ota et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals
- (2008) Michael Lefevre et al. ATHEROSCLEROSIS
- The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control
- (2008) Yasukazu Nakahata et al. CELL
- SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation
- (2008) Gad Asher et al. CELL
- Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?
- (2008) Leonard Guarente CELL
- SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
- (2008) Alexander S. Banks et al. Cell Metabolism
- The Sirtuin family: therapeutic targets to treat diseases of aging
- (2008) Jill C Milne et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Tissue-specific regulation of SIRT1 by calorie restriction
- (2008) D. Chen et al. GENES & DEVELOPMENT
- Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis
- (2008) Rui-Hong Wang et al. MOLECULAR CELL
- A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
- (2008) Yi Liu et al. NATURE
- Negative regulation of the deacetylase SIRT1 by DBC1
- (2008) Wenhui Zhao et al. NATURE
- DBC1 is a negative regulator of SIRT1
- (2008) Ja-Eun Kim et al. NATURE
- The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth
- (2008) Ron Firestein et al. PLoS One
- A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
- (2008) Jamie L. Barger et al. PLoS One
- A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
- (2008) B.-H. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sirt1 protects against high-fat diet-induced metabolic damage
- (2008) P. T. Pfluger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started